INZY vs. ARDX

Last updated Apr 2, 2026

Compare and contrast key facts about Inozyme Pharma, Inc. (INZY) and Ardelyx, Inc. (ARDX).

Performance

INZY vs. ARDX - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Inozyme Pharma, Inc. (INZY) and Ardelyx, Inc. (ARDX). The values are adjusted to include any dividend payments, if applicable.

INZY vs. ARDX - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020
INZY Inozyme Pharma, Inc.	0.00%	44.40%	-34.98%	305.71%	-84.60%	-66.96%	17.67%
ARDX Ardelyx, Inc.	4.80%	14.99%	-18.23%	117.54%	159.09%	-83.00%	2.37%

Fundamentals

Total Revenue (TTM) INZY : $0.00 ARDX : $407.32M
Gross Profit (TTM) INZY : $0.00 ARDX : $367.78M
EBITDA (TTM) INZY : -$100.34M ARDX : -$33.44M

Returns By Period

INZY

• 1D: —
• 1M: —
• YTD: —
• 6M: —
• 1Y: —
• 3Y*: —
• 5Y*: —
• 10Y*: —

ARDX

• 1D: 2.00%
• 1M: -5.56%
• YTD: 4.80%
• 6M: 13.99%
• 1Y: 27.56%
• 3Y*: 8.45%
• 5Y*: -2.29%
• 10Y*: -2.39%

*Multi-year figures are annualized to reflect compound growth (CAGR)

Return for Risk

INZY vs. ARDX — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

ARDX

ARDX Risk / Return Rank: 56
ARDX Sharpe Ratio Rank: 55
ARDX Sortino Ratio Rank: 57
ARDX Omega Ratio Rank: 57
ARDX Calmar Ratio Rank: 54
ARDX Martin Ratio Rank: 54

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

INZY vs. ARDX - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Inozyme Pharma, Inc. (INZY) and Ardelyx, Inc. (ARDX). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Risk / return metrics aren't available yet — we need at least 12 months of trading data to calculate them.

Sharpe Ratios by Period

	INZY	ARDX	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	—	0.40	—
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	—	-0.03	—
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	—	-0.03	—
Sharpe Ratio (All Time) Calculated using the full available price history	—	-0.08	—

Correlation

The correlation between INZY and ARDX is 0.23, which is considered to be low. This implies their price changes are not closely related. A low correlation is generally favorable for portfolio diversification, as it helps to reduce overall risk by spreading it across multiple assets with different performance patterns.

Dividends

INZY vs. ARDX - Dividend Comparison

Neither INZY nor ARDX has paid dividends to shareholders.

Tickers have no history of dividend payments

Drawdowns

Drawdown Indicators

	INZY	ARDX	Difference
Max Drawdown Largest peak-to-trough decline	—	-98.45%	—
Max Drawdown (1Y) Largest decline over 1 year	—	-40.42%	—
Max Drawdown (5Y) Largest decline over 5 years	—	-94.32%	—
Max Drawdown (10Y) Largest decline over 10 years	—	-96.82%	—
Current Drawdown Current decline from peak	—	-81.42%	—
Average Drawdown Average peak-to-trough decline	—	-77.32%	—
Ulcer Index Depth and duration of drawdowns from previous peaks	—	19.48%	—

Volatility

Volatility by Period

	INZY	ARDX	Difference
Volatility (1M) Calculated over the trailing 1-month period	—	16.78%	—
Volatility (6M) Calculated over the trailing 6-month period	—	50.11%	—
Volatility (1Y) Calculated over the trailing 1-year period	—	69.87%	—
Volatility (5Y) Calculated over the trailing 5-year period, annualized	—	89.97%	—
Volatility (10Y) Calculated over the trailing 10-year period, annualized	—	84.26%	—

Financials