IMMX vs. VMNIX

Last updated Apr 1, 2026

Compare and contrast key facts about Immix Biopharma, Inc. (IMMX) and Vanguard Market Neutral Fund Institutional Shares (VMNIX).

VMNIX is managed by Vanguard. It was launched on Oct 19, 1998.

Performance

IMMX vs. VMNIX - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Immix Biopharma, Inc. (IMMX) and Vanguard Market Neutral Fund Institutional Shares (VMNIX). The values are adjusted to include any dividend payments, if applicable.

IMMX vs. VMNIX - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021
IMMX Immix Biopharma, Inc.	74.19%	137.73%	-68.21%	202.18%	-35.67%	-3.00%
VMNIX Vanguard Market Neutral Fund Institutional Shares	6.12%	9.36%	5.84%	12.33%	13.47%	1.78%

Returns By Period

In the year-to-date period, IMMX achieves a 74.19% return, which is significantly higher than VMNIX's 6.12% return.

IMMX

• 1D: 6.18%
• 1M: 12.89%
• YTD: 74.19%
• 6M: 335.89%
• 1Y: 442.26%
• 3Y*: 71.06%
• 5Y*: —
• 10Y*: —

VMNIX

• 1D: 0.09%
• 1M: 3.02%
• YTD: 6.12%
• 6M: 8.21%
• 1Y: 16.09%
• 3Y*: 11.80%
• 5Y*: 12.53%
• 10Y*: 4.06%

*Multi-year figures are annualized to reflect compound growth (CAGR)

Return for Risk

IMMX vs. VMNIX — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

IMMX

IMMX Risk / Return Rank: 97
IMMX Sharpe Ratio Rank: 99
IMMX Sortino Ratio Rank: 97
IMMX Omega Ratio Rank: 94
IMMX Calmar Ratio Rank: 99
IMMX Martin Ratio Rank: 98

VMNIX

VMNIX Risk / Return Rank: 93
VMNIX Sharpe Ratio Rank: 95
VMNIX Sortino Ratio Rank: 95
VMNIX Omega Ratio Rank: 90
VMNIX Calmar Ratio Rank: 95
VMNIX Martin Ratio Rank: 88

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

IMMX vs. VMNIX - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Immix Biopharma, Inc. (IMMX) and Vanguard Market Neutral Fund Institutional Shares (VMNIX). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	IMMX	VMNIX	Difference
Sharpe ratio Return per unit of total volatility	4.90	2.20	+2.69
Sortino ratio Return per unit of downside risk	3.93	3.25	+0.68
Omega ratio Gain probability vs. loss probability	1.48	1.40	+0.08
Calmar ratio Return relative to maximum drawdown	10.94	3.37	+7.57
Martin ratio Return relative to average drawdown	25.33	9.61	+15.72
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

IMMX vs. VMNIX - Sharpe Ratio Comparison

The current IMMX Sharpe Ratio is 4.90, which is higher than the VMNIX Sharpe Ratio of 2.20. The chart below compares the historical Sharpe Ratios of IMMX and VMNIX, offering insights into how both investments have performed under varying market conditions. These values are calculated using daily returns over the previous 12 months.

Sharpe Ratios by Period

	IMMX	VMNIX	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	4.90	2.20	+2.69
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	—	1.75	—
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	—	0.64	—
Sharpe Ratio (All Time) Calculated using the full available price history	0.22	0.31	-0.10

Correlation

The correlation between IMMX and VMNIX is 0.00, which is considered to be low. This implies their price changes are not closely related. A low correlation is generally favorable for portfolio diversification, as it helps to reduce overall risk by spreading it across multiple assets with different performance patterns.

Dividends

IMMX vs. VMNIX - Dividend Comparison

IMMX has not paid dividends to shareholders, while VMNIX's dividend yield for the trailing twelve months is around 3.37%.

	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015
IMMX Immix Biopharma, Inc.	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%
VMNIX Vanguard Market Neutral Fund Institutional Shares	3.37%	3.59%	5.67%	5.15%	0.78%	0.20%	0.86%	3.23%	1.00%	1.16%	0.45%	0.10%

Drawdowns

IMMX vs. VMNIX - Drawdown Comparison

The maximum IMMX drawdown since its inception was -88.89%, which is greater than VMNIX's maximum drawdown of -27.90%. Use the drawdown chart below to compare losses from any high point for IMMX and VMNIX.

Drawdown Indicators

	IMMX	VMNIX	Difference
Max Drawdown Largest peak-to-trough decline	-88.89%	-27.90%	-60.99%
Max Drawdown (1Y) Largest decline over 1 year	-39.84%	-4.95%	-34.89%
Max Drawdown (5Y) Largest decline over 5 years	—	-6.69%	—
Max Drawdown (10Y) Largest decline over 10 years	—	-24.95%	—
Current Drawdown Current decline from peak	-18.08%	0.00%	-18.08%
Average Drawdown Average peak-to-trough decline	-60.48%	-8.82%	-51.66%
Ulcer Index Depth and duration of drawdowns from previous peaks	17.21%	1.73%	+15.48%

Volatility

IMMX vs. VMNIX - Volatility Comparison

Immix Biopharma, Inc. (IMMX) has a higher volatility of 27.27% compared to Vanguard Market Neutral Fund Institutional Shares (VMNIX) at 1.54%. This indicates that IMMX's price experiences larger fluctuations and is considered to be riskier than VMNIX based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	IMMX	VMNIX	Difference
Volatility (1M) Calculated over the trailing 1-month period	27.27%	1.54%	+25.73%
Volatility (6M) Calculated over the trailing 6-month period	64.64%	5.73%	+58.91%
Volatility (1Y) Calculated over the trailing 1-year period	91.11%	7.59%	+83.52%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	110.66%	7.19%	+103.47%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	110.66%	6.35%	+104.31%