ILMN vs. TTD

Last updated Apr 1, 2026

Compare and contrast key facts about Illumina, Inc. (ILMN) and The Trade Desk, Inc. (TTD).

Performance

ILMN vs. TTD - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Illumina, Inc. (ILMN) and The Trade Desk, Inc. (TTD). The values are adjusted to include any dividend payments, if applicable.

ILMN vs. TTD - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019	2018	2017
ILMN Illumina, Inc.	-6.02%	-1.85%	-1.34%	-31.14%	-46.85%	2.82%	11.53%	10.61%	37.27%	70.64%
TTD The Trade Desk, Inc.	-40.23%	-67.70%	63.33%	60.52%	-51.08%	14.41%	208.34%	123.83%	153.79%	65.27%

Fundamentals

Market Cap ILMN : $18.98B TTD : $10.95B
EPS ILMN : $5.44 TTD : $0.90
PE Ratio ILMN : 22.67 TTD : 25.11
PEG Ratio ILMN : 10.89 TTD : 0.33
PS Ratio ILMN : 4.44 TTD : 3.84
PB Ratio ILMN : 6.16 TTD : 4.41
Total Revenue (TTM) ILMN : $4.34B TTD : $2.90B
Gross Profit (TTM) ILMN : $2.89B TTD : $2.28B
EBITDA (TTM) ILMN : $1.46B TTD : $691.45M

Returns By Period

In the year-to-date period, ILMN achieves a -6.02% return, which is significantly higher than TTD's -40.23% return.

ILMN

• 1D: 2.03%
• 1M: -8.33%
• YTD: -6.02%
• 6M: 29.79%
• 1Y: 55.36%
• 3Y*: -18.32%
• 5Y*: -19.93%
• 10Y*: -2.71%

TTD

• 1D: 3.09%
• 1M: -4.74%
• YTD: -40.23%
• 6M: -53.70%
• 1Y: -58.53%
• 3Y*: -28.05%
• 5Y*: -19.20%
• 10Y*: —

*Multi-year figures are annualized to reflect compound growth (CAGR)

Return for Risk

ILMN vs. TTD — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

ILMN

ILMN Risk / Return Rank: 77
ILMN Sharpe Ratio Rank: 78
ILMN Sortino Ratio Rank: 78
ILMN Omega Ratio Rank: 73
ILMN Calmar Ratio Rank: 79
ILMN Martin Ratio Rank: 78

TTD

TTD Risk / Return Rank: 11
TTD Sharpe Ratio Rank: 8
TTD Sortino Ratio Rank: 10
TTD Omega Ratio Rank: 8
TTD Calmar Ratio Rank: 14
TTD Martin Ratio Rank: 17

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

ILMN vs. TTD - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Illumina, Inc. (ILMN) and The Trade Desk, Inc. (TTD). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	ILMN	TTD	Difference
Sharpe ratio Return per unit of total volatility	1.14	-0.84	+1.98
Sortino ratio Return per unit of downside risk	1.94	-1.14	+3.08
Omega ratio Gain probability vs. loss probability	1.23	0.83	+0.41
Calmar ratio Return relative to maximum drawdown	2.11	-0.78	+2.89
Martin ratio Return relative to average drawdown	5.22	-1.30	+6.52
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

ILMN vs. TTD - Sharpe Ratio Comparison

The current ILMN Sharpe Ratio is 1.14, which is higher than the TTD Sharpe Ratio of -0.84. The chart below compares the historical Sharpe Ratios of ILMN and TTD, offering insights into how both investments have performed under varying market conditions. These values are calculated using daily returns over the previous 12 months.

Sharpe Ratios by Period

	ILMN	TTD	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	1.14	-0.84	+1.98
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	-0.44	-0.28	-0.16
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	-0.06	—	—
Sharpe Ratio (All Time) Calculated using the full available price history	0.13	0.35	-0.21

Correlation

The correlation between ILMN and TTD is 0.40, which is considered to be moderate. This suggests that the two assets have some degree of positive relationship in their price movements. Moderate correlation can be acceptable for portfolio diversification, offering a balance between risk and potential returns.

Dividends

ILMN vs. TTD - Dividend Comparison

Neither ILMN nor TTD has paid dividends to shareholders.

Tickers have no history of dividend payments

Drawdowns

ILMN vs. TTD - Drawdown Comparison

The maximum ILMN drawdown since its inception was -96.14%, which is greater than TTD's maximum drawdown of -84.75%. Use the drawdown chart below to compare losses from any high point for ILMN and TTD.

Drawdown Indicators

	ILMN	TTD	Difference
Max Drawdown Largest peak-to-trough decline	-96.14%	-84.75%	-11.39%
Max Drawdown (1Y) Largest decline over 1 year	-25.66%	-76.29%	+50.63%
Max Drawdown (5Y) Largest decline over 5 years	-86.23%	-84.75%	-1.48%
Max Drawdown (10Y) Largest decline over 10 years	-86.23%	—	—
Current Drawdown Current decline from peak	-75.86%	-83.74%	+7.88%
Average Drawdown Average peak-to-trough decline	-40.15%	-26.07%	-14.08%
Ulcer Index Depth and duration of drawdowns from previous peaks	10.36%	45.80%	-35.44%

Volatility

ILMN vs. TTD - Volatility Comparison

The current volatility for Illumina, Inc. (ILMN) is 10.88%, while The Trade Desk, Inc. (TTD) has a volatility of 23.19%. This indicates that ILMN experiences smaller price fluctuations and is considered to be less risky than TTD based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	ILMN	TTD	Difference
Volatility (1M) Calculated over the trailing 1-month period	10.88%	23.19%	-12.31%
Volatility (6M) Calculated over the trailing 6-month period	36.52%	35.50%	+1.02%
Volatility (1Y) Calculated over the trailing 1-year period	49.01%	69.70%	-20.69%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	45.30%	67.88%	-22.58%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	42.62%	68.59%	-25.97%

Financials

ILMN vs. TTD - Profitability Comparison

The chart below illustrates the profitability comparison between Illumina, Inc. and The Trade Desk, Inc. over time, highlighting three key metrics: Gross Profit Margin, Operating Margin, and Net Profit Margin.

ILMN - Gross Margin

Gross margin is calculated as gross profit divided by revenue. For the three months ending on Apr 2026, Illumina, Inc. reported a gross profit of 777.00M and revenue of 1.16B. Therefore, the gross margin over that period was 67.0%.

TTD - Gross Margin

Gross margin is calculated as gross profit divided by revenue. For the three months ending on Apr 2026, The Trade Desk, Inc. reported a gross profit of 683.70M and revenue of 846.79M. Therefore, the gross margin over that period was 80.7%.

ILMN - Operating Margin

Operating margin is calculated as operating income divided by revenue. For the three months ending on Apr 2026, Illumina, Inc. reported an operating income of 256.00M and revenue of 1.16B, resulting in an operating margin of 22.1%.

TTD - Operating Margin

Operating margin is calculated as operating income divided by revenue. For the three months ending on Apr 2026, The Trade Desk, Inc. reported an operating income of 256.87M and revenue of 846.79M, resulting in an operating margin of 30.3%.

ILMN - Net Margin

Net margin is calculated as net income divided by revenue. For the three months ending on Apr 2026, Illumina, Inc. reported a net income of 334.00M and revenue of 1.16B, resulting in a net margin of 28.8%.

TTD - Net Margin

Net margin is calculated as net income divided by revenue. For the three months ending on Apr 2026, The Trade Desk, Inc. reported a net income of 186.95M and revenue of 846.79M, resulting in a net margin of 22.1%.