IDXX vs. ZTS

Last updated Apr 2, 2026

Compare and contrast key facts about IDEXX Laboratories, Inc. (IDXX) and Zoetis Inc. (ZTS).

Performance

IDXX vs. ZTS - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in IDEXX Laboratories, Inc. (IDXX) and Zoetis Inc. (ZTS). The values are adjusted to include any dividend payments, if applicable.

IDXX vs. ZTS - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019	2018	2017
IDXX IDEXX Laboratories, Inc.	-16.54%	63.63%	-25.51%	36.06%	-38.04%	31.73%	91.43%	40.38%	18.95%	33.35%
ZTS Zoetis Inc.	-6.38%	-21.75%	-16.63%	35.91%	-39.51%	48.26%	25.76%	55.71%	19.45%	35.55%

Fundamentals

Market Cap IDXX : $45.55B ZTS : $51.44B
EPS IDXX : $13.12 ZTS : $6.04
PE Ratio IDXX : 43.05 ZTS : 19.41
PEG Ratio IDXX : 9.81 ZTS : 2.18
PS Ratio IDXX : 10.60 ZTS : 5.48
PB Ratio IDXX : 28.38 ZTS : 15.44
Total Revenue (TTM) IDXX : $4.30B ZTS : $9.47B
Gross Profit (TTM) IDXX : $2.66B ZTS : $6.67B
EBITDA (TTM) IDXX : $1.47B ZTS : $4.09B

Returns By Period

In the year-to-date period, IDXX achieves a -16.54% return, which is significantly lower than ZTS's -6.38% return. Over the past 10 years, IDXX has outperformed ZTS with an annualized return of 21.68%, while ZTS has yielded a comparatively lower 10.95% annualized return.

IDXX

• 1D: 0.49%
• 1M: -11.31%
• YTD: -16.54%
• 6M: -8.94%
• 1Y: 34.90%
• 3Y*: 4.13%
• 5Y*: 3.03%
• 10Y*: 21.68%

ZTS

• 1D: -0.78%
• 1M: -9.05%
• YTD: -6.38%
• 6M: -19.56%
• 1Y: -26.50%
• 3Y*: -10.00%
• 5Y*: -4.87%
• 10Y*: 10.95%

*Multi-year figures are annualized to reflect compound growth (CAGR)

Return for Risk

IDXX vs. ZTS — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

IDXX

IDXX Risk / Return Rank: 70
IDXX Sharpe Ratio Rank: 68
IDXX Sortino Ratio Rank: 74
IDXX Omega Ratio Rank: 72
IDXX Calmar Ratio Rank: 67
IDXX Martin Ratio Rank: 69

ZTS

ZTS Risk / Return Rank: 8
ZTS Sharpe Ratio Rank: 6
ZTS Sortino Ratio Rank: 9
ZTS Omega Ratio Rank: 8
ZTS Calmar Ratio Rank: 10
ZTS Martin Ratio Rank: 10

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

IDXX vs. ZTS - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for IDEXX Laboratories, Inc. (IDXX) and Zoetis Inc. (ZTS). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	IDXX	ZTS	Difference
Sharpe ratio Return per unit of total volatility	0.80	-0.92	+1.72
Sortino ratio Return per unit of downside risk	1.84	-1.15	+2.99
Omega ratio Gain probability vs. loss probability	1.24	0.84	+0.39
Calmar ratio Return relative to maximum drawdown	1.26	-0.85	+2.11
Martin ratio Return relative to average drawdown	3.45	-1.46	+4.91
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

IDXX vs. ZTS - Sharpe Ratio Comparison

The current IDXX Sharpe Ratio is 0.80, which is higher than the ZTS Sharpe Ratio of -0.92. The chart below compares the historical Sharpe Ratios of IDXX and ZTS, offering insights into how both investments have performed under varying market conditions. These values are calculated using daily returns over the previous 12 months.

Sharpe Ratios by Period

	IDXX	ZTS	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	0.80	-0.92	+1.72
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	0.09	-0.18	+0.27
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	0.66	0.42	+0.24
Sharpe Ratio (All Time) Calculated using the full available price history	0.51	0.45	+0.06

Correlation

The correlation between IDXX and ZTS is 0.56, which is considered to be moderate. This suggests that the two assets have some degree of positive relationship in their price movements. Moderate correlation can be acceptable for portfolio diversification, offering a balance between risk and potential returns.

Dividends

IDXX vs. ZTS - Dividend Comparison

IDXX has not paid dividends to shareholders, while ZTS's dividend yield for the trailing twelve months is around 1.73%.

	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015
IDXX IDEXX Laboratories, Inc.	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%
ZTS Zoetis Inc.	1.73%	1.59%	1.06%	0.76%	0.89%	0.41%	0.48%	0.50%	0.59%	0.58%	0.71%	0.69%

Drawdowns

IDXX vs. ZTS - Drawdown Comparison

The maximum IDXX drawdown since its inception was -81.42%, which is greater than ZTS's maximum drawdown of -52.06%. Use the drawdown chart below to compare losses from any high point for IDXX and ZTS.

Drawdown Indicators

	IDXX	ZTS	Difference
Max Drawdown Largest peak-to-trough decline	-81.42%	-52.06%	-29.36%
Max Drawdown (1Y) Largest decline over 1 year	-27.34%	-32.70%	+5.36%
Max Drawdown (5Y) Largest decline over 5 years	-54.00%	-52.06%	-1.94%
Max Drawdown (10Y) Largest decline over 10 years	-54.00%	-52.06%	-1.94%
Current Drawdown Current decline from peak	-26.35%	-50.40%	+24.05%
Average Drawdown Average peak-to-trough decline	-20.98%	-14.19%	-6.79%
Ulcer Index Depth and duration of drawdowns from previous peaks	9.98%	19.04%	-9.06%

Volatility

IDXX vs. ZTS - Volatility Comparison

IDEXX Laboratories, Inc. (IDXX) and Zoetis Inc. (ZTS) have volatilities of 8.63% and 8.63%, respectively, indicating that both stocks experience similar levels of price fluctuations. This suggests that the risk associated with both stocks, as measured by volatility, is nearly the same. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	IDXX	ZTS	Difference
Volatility (1M) Calculated over the trailing 1-month period	8.63%	8.63%	0.00%
Volatility (6M) Calculated over the trailing 6-month period	23.61%	22.33%	+1.28%
Volatility (1Y) Calculated over the trailing 1-year period	43.76%	29.04%	+14.72%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	35.10%	26.57%	+8.53%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	32.84%	25.94%	+6.90%

Financials

IDXX vs. ZTS - Profitability Comparison

The chart below illustrates the profitability comparison between IDEXX Laboratories, Inc. and Zoetis Inc. over time, highlighting three key metrics: Gross Profit Margin, Operating Margin, and Net Profit Margin.

IDXX - Gross Margin

Gross margin is calculated as gross profit divided by revenue. For the three months ending on Apr 2026, IDEXX Laboratories, Inc. reported a gross profit of 658.11M and revenue of 1.09B. Therefore, the gross margin over that period was 60.4%.

ZTS - Gross Margin

Gross margin is calculated as gross profit divided by revenue. For the three months ending on Apr 2026, Zoetis Inc. reported a gross profit of 1.64B and revenue of 2.39B. Therefore, the gross margin over that period was 68.9%.

IDXX - Operating Margin

Operating margin is calculated as operating income divided by revenue. For the three months ending on Apr 2026, IDEXX Laboratories, Inc. reported an operating income of 315.61M and revenue of 1.09B, resulting in an operating margin of 28.9%.

ZTS - Operating Margin

Operating margin is calculated as operating income divided by revenue. For the three months ending on Apr 2026, Zoetis Inc. reported an operating income of 826.00M and revenue of 2.39B, resulting in an operating margin of 34.6%.

IDXX - Net Margin

Net margin is calculated as net income divided by revenue. For the three months ending on Apr 2026, IDEXX Laboratories, Inc. reported a net income of 248.19M and revenue of 1.09B, resulting in a net margin of 22.8%.

ZTS - Net Margin

Net margin is calculated as net income divided by revenue. For the three months ending on Apr 2026, Zoetis Inc. reported a net income of 603.00M and revenue of 2.39B, resulting in a net margin of 25.3%.