IART vs. HOLX

Last updated Apr 1, 2026

Compare and contrast key facts about Integra LifeSciences Holdings Corporation (IART) and Hologic, Inc. (HOLX).

Performance

IART vs. HOLX - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Integra LifeSciences Holdings Corporation (IART) and Hologic, Inc. (HOLX). The values are adjusted to include any dividend payments, if applicable.

IART vs. HOLX - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019	2018	2017
IART Integra LifeSciences Holdings Corporation	-24.15%	-45.24%	-47.92%	-22.33%	-16.30%	3.19%	11.39%	29.22%	-5.77%	11.57%
HOLX Hologic, Inc.	1.48%	3.33%	0.90%	-4.49%	-2.29%	5.12%	39.49%	27.03%	-3.86%	6.56%

Fundamentals

EPS IART : -$10.11 HOLX : $2.41
PS Ratio IART : 0.29 HOLX : 4.13
Total Revenue (TTM) IART : $1.64B HOLX : $4.13B
Gross Profit (TTM) IART : $629.87M HOLX : $2.18B
EBITDA (TTM) IART : -$369.15M HOLX : $1.01B

Returns By Period

In the year-to-date period, IART achieves a -24.15% return, which is significantly lower than HOLX's 1.48% return. Over the past 10 years, IART has underperformed HOLX with an annualized return of -11.98%, while HOLX has yielded a comparatively higher 8.13% annualized return.

IART

• 1D: 3.29%
• 1M: -17.22%
• YTD: -24.15%
• 6M: -34.26%
• 1Y: -57.16%
• 3Y*: -45.25%
• 5Y*: -32.67%
• 10Y*: -11.98%

HOLX

• 1D: 0.05%
• 1M: 0.31%
• YTD: 1.48%
• 6M: 12.00%
• 1Y: 22.37%
• 3Y*: -2.16%
• 5Y*: 0.33%
• 10Y*: 8.13%

*Multi-year figures are annualized to reflect compound growth (CAGR)

Return for Risk

IART vs. HOLX — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

IART

IART Risk / Return Rank: 8
IART Sharpe Ratio Rank: 6
IART Sortino Ratio Rank: 7
IART Omega Ratio Rank: 7
IART Calmar Ratio Rank: 5
IART Martin Ratio Rank: 13

HOLX

HOLX Risk / Return Rank: 75
HOLX Sharpe Ratio Rank: 72
HOLX Sortino Ratio Rank: 72
HOLX Omega Ratio Rank: 76
HOLX Calmar Ratio Rank: 73
HOLX Martin Ratio Rank: 82

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

IART vs. HOLX - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Integra LifeSciences Holdings Corporation (IART) and Hologic, Inc. (HOLX). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	IART	HOLX	Difference
Sharpe ratio Return per unit of total volatility	-0.93	0.90	-1.83
Sortino ratio Return per unit of downside risk	-1.33	1.67	-3.00
Omega ratio Gain probability vs. loss probability	0.83	1.25	-0.43
Calmar ratio Return relative to maximum drawdown	-0.95	1.59	-2.54
Martin ratio Return relative to average drawdown	-1.37	6.62	-7.99
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

IART vs. HOLX - Sharpe Ratio Comparison

The current IART Sharpe Ratio is -0.93, which is lower than the HOLX Sharpe Ratio of 0.90. The chart below compares the historical Sharpe Ratios of IART and HOLX, offering insights into how both investments have performed under varying market conditions. These values are calculated using daily returns over the previous 12 months.

Sharpe Ratios by Period

	IART	HOLX	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	-0.93	0.90	-1.83
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	-0.74	0.01	-0.75
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	-0.31	0.31	-0.62
Sharpe Ratio (All Time) Calculated using the full available price history	0.06	0.19	-0.13

Correlation

The correlation between IART and HOLX is 0.28, which is considered to be low. This implies their price changes are not closely related. A low correlation is generally favorable for portfolio diversification, as it helps to reduce overall risk by spreading it across multiple assets with different performance patterns.

Dividends

IART vs. HOLX - Dividend Comparison

Neither IART nor HOLX has paid dividends to shareholders.

	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015
IART Integra LifeSciences Holdings Corporation	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	9.40%
HOLX Hologic, Inc.	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%

Drawdowns

IART vs. HOLX - Drawdown Comparison

The maximum IART drawdown since its inception was -88.39%, smaller than the maximum HOLX drawdown of -93.75%. Use the drawdown chart below to compare losses from any high point for IART and HOLX.

Drawdown Indicators

	IART	HOLX	Difference
Max Drawdown Largest peak-to-trough decline	-88.39%	-93.75%	+5.36%
Max Drawdown (1Y) Largest decline over 1 year	-59.14%	-14.52%	-44.62%
Max Drawdown (5Y) Largest decline over 5 years	-88.39%	-39.85%	-48.54%
Max Drawdown (10Y) Largest decline over 10 years	-88.39%	-46.24%	-42.15%
Current Drawdown Current decline from peak	-87.71%	-13.78%	-73.93%
Average Drawdown Average peak-to-trough decline	-29.36%	-40.25%	+10.89%
Ulcer Index Depth and duration of drawdowns from previous peaks	41.34%	3.51%	+37.83%

Volatility

IART vs. HOLX - Volatility Comparison

Integra LifeSciences Holdings Corporation (IART) has a higher volatility of 10.87% compared to Hologic, Inc. (HOLX) at 0.75%. This indicates that IART's price experiences larger fluctuations and is considered to be riskier than HOLX based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	IART	HOLX	Difference
Volatility (1M) Calculated over the trailing 1-month period	10.87%	0.75%	+10.12%
Volatility (6M) Calculated over the trailing 6-month period	42.46%	7.02%	+35.44%
Volatility (1Y) Calculated over the trailing 1-year period	61.56%	24.91%	+36.65%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	44.54%	23.12%	+21.42%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	38.34%	26.51%	+11.83%

Financials

IART vs. HOLX - Profitability Comparison

The chart below illustrates the profitability comparison between Integra LifeSciences Holdings Corporation and Hologic, Inc. over time, highlighting three key metrics: Gross Profit Margin, Operating Margin, and Net Profit Margin.

IART - Gross Margin

Gross margin is calculated as gross profit divided by revenue. For the three months ending on Apr 2026, Integra LifeSciences Holdings Corporation reported a gross profit of 0.00 and revenue of 434.93M. Therefore, the gross margin over that period was 0.0%.

HOLX - Gross Margin

Gross margin is calculated as gross profit divided by revenue. For the three months ending on Apr 2026, Hologic, Inc. reported a gross profit of 586.40M and revenue of 1.05B. Therefore, the gross margin over that period was 56.0%.

IART - Operating Margin

Operating margin is calculated as operating income divided by revenue. For the three months ending on Apr 2026, Integra LifeSciences Holdings Corporation reported an operating income of -5.49M and revenue of 434.93M, resulting in an operating margin of -1.3%.

HOLX - Operating Margin

Operating margin is calculated as operating income divided by revenue. For the three months ending on Apr 2026, Hologic, Inc. reported an operating income of 237.00M and revenue of 1.05B, resulting in an operating margin of 22.6%.

IART - Net Margin

Net margin is calculated as net income divided by revenue. For the three months ending on Apr 2026, Integra LifeSciences Holdings Corporation reported a net income of -1.70M and revenue of 434.93M, resulting in a net margin of -0.4%.

HOLX - Net Margin

Net margin is calculated as net income divided by revenue. For the three months ending on Apr 2026, Hologic, Inc. reported a net income of 179.10M and revenue of 1.05B, resulting in a net margin of 17.1%.