GRTX vs. FXAIX

Last updated Jul 11, 2026

GRTX (Galera Therapeutics, Inc.) is a stock, while FXAIX (Fidelity 500 Index Fund) is S&P 500 fund tracking the S&P 500 Index. Over the past 5 years, GRTX returned -61.30%/yr vs 13.14%/yr for FXAIX. At a 0.15 correlation, their price movements are largely independent.

Performance

GRTX vs. FXAIX - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Galera Therapeutics, Inc. (GRTX) and Fidelity 500 Index Fund (FXAIX). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, GRTX achieves a 300.00% return, which is significantly higher than FXAIX's 10.87% return.

GRTX

• 1D: -2.22%
• 1M: -4.09%
• 6M: 275.43%
• YTD: 300.00%
• 1Y: 225.93%
• 3Y*: -68.70%
• 5Y*: -61.30%
• 10Y*: —

FXAIX

• 1D: 0.82%
• 1M: 1.58%
• 6M: 8.91%
• YTD: 10.87%
• 1Y: 21.93%
• 3Y*: 21.20%
• 5Y*: 13.14%
• 10Y*: 15.35%

*Multi-year figures are annualized to reflect compound growth (CAGR)

GRTX vs. FXAIX - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019
GRTX Galera Therapeutics, Inc.	300.00%	-51.97%	-68.50%	-90.24%	-67.54%	-55.13%	-22.26%	5.28%
FXAIX Fidelity 500 Index Fund	10.87%	17.84%	25.01%	26.29%	-18.14%	28.71%	18.42%	5.37%

Correlation

The correlation between GRTX and FXAIX is 0.06, meaning there is essentially no relationship between their price movements. Each responds to its own set of market drivers, making them strong candidates for combining in a diversified portfolio.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.06
Correlation (3Y) Calculated over the trailing 3-year period	0.05
Correlation (5Y) Calculated over the trailing 5-year period	0.13
Correlation (All Time) Calculated using the full available price history since Nov 7, 2019	0.15

The correlation between GRTX and FXAIX shifts across timeframes, from 0.05 (3 years) to 0.15 (all time), reflecting how their relationship changes across market environments.

Return for Risk

GRTX vs. FXAIX — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

GRTX

GRTX Risk / Return Rank: 92
GRTX Sharpe Ratio Rank: 88
GRTX Sortino Ratio Rank: 94
GRTX Omega Ratio Rank: 92
GRTX Calmar Ratio Rank: 94
GRTX Martin Ratio Rank: 91

FXAIX

FXAIX Risk / Return Rank: 65
FXAIX Sharpe Ratio Rank: 64
FXAIX Sortino Ratio Rank: 59
FXAIX Omega Ratio Rank: 61
FXAIX Calmar Ratio Rank: 65
FXAIX Martin Ratio Rank: 77

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

GRTX vs. FXAIX - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Galera Therapeutics, Inc. (GRTX) and Fidelity 500 Index Fund (FXAIX). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.

	GRTX	FXAIX	Difference
Sharpe ratio: Return per unit of total volatility	1.65	1.76	-0.10
Sortino ratio: Return per unit of downside risk	3.32	2.42	+0.90
Omega ratio: Gain probability vs. loss probability	1.40	1.32	+0.08
Calmar ratio: Return relative to maximum drawdown	4.98	2.47	+2.51
Martin ratio: Return relative to average drawdown	10.30	10.85	-0.54

GRTX vs. FXAIX - Sharpe Ratio Comparison

The current GRTX Sharpe Ratio is 1.65, which is comparable to the FXAIX Sharpe Ratio of 1.76. The chart below compares the historical Sharpe Ratios of GRTX and FXAIX, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Drawdowns

GRTX vs. FXAIX - Drawdown Comparison

The maximum GRTX drawdown since its inception was -99.91%, which is greater than FXAIX's maximum drawdown of -33.79%. Use the drawdown chart below to compare losses from any high point for GRTX and FXAIX.

Drawdown Indicators

	GRTX	FXAIX	Difference
Max Drawdown Largest peak-to-trough decline	-99.91%	-33.79%	-66.12%
Max Drawdown (1Y) Largest decline over 1 year	-46.67%	-8.89%	-37.78%
Max Drawdown (3Y) Largest decline over 3 years	-99.46%	-18.76%	-80.70%
Max Drawdown (5Y) Largest decline over 5 years	-99.84%	-24.50%	-75.34%
Max Drawdown (10Y) Largest decline over 10 years	—	-33.79%	—
Current Drawdown Current decline from peak	-99.50%	-0.74%	-98.76%
Average Drawdown Average peak-to-trough decline	-79.11%	-3.78%	-75.33%
Ulcer Index Depth and duration of drawdowns from previous peaks	22.51%	2.02%	+20.49%

Volatility

GRTX vs. FXAIX - Volatility Comparison

Galera Therapeutics, Inc. (GRTX) has a higher volatility of 15.99% compared to Fidelity 500 Index Fund (FXAIX) at 4.27%. This indicates that GRTX's price experiences larger fluctuations and is considered to be riskier than FXAIX based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	GRTX	FXAIX	Difference
Volatility (1M) Calculated over the trailing 1-month period	15.99%	4.27%	+11.72%
Volatility (6M) Calculated over the trailing 6-month period	89.53%	9.96%	+79.57%
Volatility (1Y) Calculated over the trailing 1-year period	140.68%	12.53%	+128.15%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	135.42%	17.02%	+118.40%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	124.89%	18.05%	+106.84%

Dividends

GRTX vs. FXAIX - Dividend Comparison

GRTX has not paid dividends to shareholders, while FXAIX's dividend yield for the trailing twelve months is around 1.03%.

Position	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015
FXAIX Fidelity 500 Index Fund	0.79%	1.11%	1.25%	1.45%	1.69%	1.22%	1.60%	2.06%	2.72%	1.97%	2.52%	2.83%
GRTX Galera Therapeutics, Inc.	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%

Frequently Asked Questions

Can I hold both GRTX and FXAIX in my portfolio?

GRTX and FXAIX have a correlation of 0.06, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, GRTX or FXAIX?

GRTX has higher volatility (15.99%) compared to FXAIX (4.27%). In terms of maximum drawdown, GRTX dropped -99.91% vs FXAIX's -33.79%.

Which has better risk-adjusted returns?

FXAIX currently has the higher Sharpe Ratio (1.76 vs 1.65), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.