GANX vs. SEER

Last updated Jun 4, 2026

GANX (Gain Therapeutics, Inc.) and SEER (Seer, Inc.) are both stocks. Both operate in the Biotechnology industry within the Healthcare sector. Over the past 5 years, GANX returned -29.99%/yr vs -43.80%/yr for SEER. At a 0.21 correlation, their price movements are largely independent.

Performance

GANX vs. SEER - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Gain Therapeutics, Inc. (GANX) and Seer, Inc. (SEER). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, GANX achieves a -44.41% return, which is significantly lower than SEER's 1.64% return.

GANX

• 1D: -2.19%
• 1M: -5.79%
• YTD: -44.41%
• 6M: -46.08%
• 1Y: -10.95%
• 3Y*: -28.66%
• 5Y*: -29.99%
• 10Y*: —

SEER

• 1D: -0.53%
• 1M: -4.62%
• YTD: 1.64%
• 6M: -1.59%
• 1Y: -13.08%
• 3Y*: -22.97%
• 5Y*: -43.80%
• 10Y*: —

*Multi-year figures are annualized to reflect compound growth (CAGR)

GANX vs. SEER - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021
GANX Gain Therapeutics, Inc.	-44.41%	49.07%	-33.84%	4.31%	-42.36%	-51.52%
SEER Seer, Inc.	1.64%	-20.78%	19.07%	-66.55%	-74.57%	-53.07%

Correlation

The correlation between GANX and SEER is 0.16, which is low. Their price movements are largely independent, making them effective diversification partners.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.16
Correlation (3Y) Calculated over the trailing 3-year period	0.15
Correlation (5Y) Calculated over the trailing 5-year period	0.21
Correlation (All Time) Calculated using the full available price history since Mar 19, 2021	0.21

Fundamentals

Market Cap GANX : $75.59M SEER : $104.15M
EPS GANX : -$0.60 SEER : -$1.24
PB Ratio GANX : 5.40 SEER : 0.43
Total Revenue (TTM) GANX : $0.00 SEER : $15.17M
Gross Profit (TTM) GANX : $2.13M SEER : $7.39M
EBITDA (TTM) GANX : -$19.59M SEER : -$63.20M

Return for Risk

GANX vs. SEER — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

GANX

GANX Risk / Return Rank: 40
GANX Sharpe Ratio Rank: 37
GANX Sortino Ratio Rank: 47
GANX Omega Ratio Rank: 47
GANX Calmar Ratio Rank: 35
GANX Martin Ratio Rank: 36

SEER

SEER Risk / Return Rank: 27
SEER Sharpe Ratio Rank: 28
SEER Sortino Ratio Rank: 27
SEER Omega Ratio Rank: 26
SEER Calmar Ratio Rank: 26
SEER Martin Ratio Rank: 26

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

GANX vs. SEER - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Gain Therapeutics, Inc. (GANX) and Seer, Inc. (SEER). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	GANX	SEER	Difference
Sharpe ratio: Return per unit of total volatility	-0.10	-0.31	+0.21
Sortino ratio: Return per unit of downside risk	0.69	-0.18	+0.87
Omega ratio: Gain probability vs. loss probability	1.09	0.98	+0.11
Calmar ratio: Return relative to maximum drawdown	-0.18	-0.44	+0.26
Martin ratio: Return relative to average drawdown	-0.31	-0.77	+0.46
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

GANX vs. SEER - Sharpe Ratio Comparison

The current GANX Sharpe Ratio is -0.10, which is higher than the SEER Sharpe Ratio of -0.31. The chart below compares the historical Sharpe Ratios of GANX and SEER, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Sharpe Ratios by Period

	GANX	SEER	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	-0.10	-0.31	+0.21
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	-0.35	-0.59	+0.25
Sharpe Ratio (All Time) Calculated using the full available price history	-0.35	-0.60	+0.25

Drawdowns

GANX vs. SEER - Drawdown Comparison

The maximum GANX drawdown since its inception was -94.08%, roughly equal to the maximum SEER drawdown of -98.25%. Use the drawdown chart below to compare losses from any high point for GANX and SEER.

Drawdown Indicators

	GANX	SEER	Difference
Max Drawdown Largest peak-to-trough decline	-94.08%	-98.25%	+4.17%
Max Drawdown (1Y) Largest decline over 1 year	-61.96%	-29.96%	-32.00%
Max Drawdown (3Y) Largest decline over 3 years	-81.50%	-73.37%	-8.13%
Max Drawdown (5Y) Largest decline over 5 years	-91.21%	-96.74%	+5.53%
Current Drawdown Current decline from peak	-88.67%	-97.79%	+9.12%
Average Drawdown Average peak-to-trough decline	-75.45%	-86.19%	+10.74%
Ulcer Index Depth and duration of drawdowns from previous peaks	35.32%	17.10%	+18.22%

Volatility

GANX vs. SEER - Volatility Comparison

Gain Therapeutics, Inc. (GANX) has a higher volatility of 20.65% compared to Seer, Inc. (SEER) at 10.69%. This indicates that GANX's price experiences larger fluctuations and is considered to be riskier than SEER based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	GANX	SEER	Difference
Volatility (1M) Calculated over the trailing 1-month period	20.65%	10.69%	+9.96%
Volatility (6M) Calculated over the trailing 6-month period	95.26%	33.15%	+62.11%
Volatility (1Y) Calculated over the trailing 1-year period	110.06%	42.69%	+67.37%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	86.16%	73.88%	+12.28%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	85.42%	77.22%	+8.20%

Dividends

GANX vs. SEER - Dividend Comparison

Neither GANX nor SEER has paid dividends to shareholders.

Tickers have no history of dividend payments

Financials

Frequently Asked Questions

Can I hold both GANX and SEER in my portfolio?

GANX and SEER have a correlation of 0.16, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, GANX or SEER?

GANX has higher volatility (20.65%) compared to SEER (10.69%). In terms of maximum drawdown, GANX dropped -94.08% vs SEER's -98.25%.

Which has better risk-adjusted returns?

GANX currently has the higher Sharpe Ratio (-0.10 vs -0.31), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.