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FULC vs. MELI
Performance
Return for Risk
Drawdowns
Volatility
Dividends
Financials

Performance

FULC vs. MELI - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Fulcrum Therapeutics, Inc. (FULC) and MercadoLibre, Inc. (MELI). The values are adjusted to include any dividend payments, if applicable.

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Returns By Period

In the year-to-date period, FULC achieves a -68.35% return, which is significantly lower than MELI's -6.77% return.


FULC

1D
-3.76%
1M
-6.77%
6M
-66.64%
YTD
-68.35%
1Y
-47.58%
3Y*
-1.18%
5Y*
-13.31%
10Y*
ALL TIME*
-18.03%

MELI

1D
-0.41%
1M
6.50%
6M
-12.56%
YTD
-6.77%
1Y
-20.96%
3Y*
15.77%
5Y*
3.66%
10Y*
28.68%
ALL TIME*
26.62%
*Multi-year figures are annualized to reflect compound growth (CAGR)

Liquidity Comparison


PositionAvg. Volume Value (2W)Avg. Volume Value (1M)Avg. Volume Value (3M)
$4.67M$5.87M$9.42M
$585.82M$641.09M$903.00M

FULC vs. MELI - Yearly Performance Comparison


2026 (YTD)2025202420232022202120202019
FULC
Fulcrum Therapeutics, Inc.
-68.35%140.64%-30.37%-7.28%-58.85%51.07%-29.63%14.76%
MELI
MercadoLibre, Inc.
-6.77%18.46%8.20%85.71%-37.24%-19.51%192.90%-9.46%

Correlation

The correlation between FULC and MELI is 0.16, which is low. Their historical price movements had little consistent relationship.


Correlation
Correlation (1Y)
Focuses on recent behavior, but can change the most.

0.16

Correlation (3Y)
Balances recent behavior with more history.

0.21

Correlation (5Y)
Shows whether the relationship held over a longer period.

0.25

Correlation (All Time)
Calculated using the full available price history since Jul 18, 2019

0.25

Fundamentals

Market Cap

FULC:

$193.72M

MELI:

$95.21B

EPS

FULC:

-$1.22

MELI:

$37.87

PB Ratio

FULC:

0.88

MELI:

13.08

Total Revenue (TTM)

FULC:

$0.00

MELI:

$30.67B

Gross Profit (TTM)

FULC:

-$14.33M

MELI:

$13.95B

EBITDA (TTM)

FULC:

-$87.10M

MELI:

$3.11B

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Return for Risk

FULC vs. MELI — Risk / Return Rank

Compare historical risk-adjusted metric ranks over the past 12 months.

FULC
FULC Risk / Return Rank: 2424
Overall Rank
FULC Sharpe Ratio Rank: 2222
Sharpe Ratio Rank
FULC Sortino Ratio Rank: 3030
Sortino Ratio Rank
FULC Omega Ratio Rank: 2929
Omega Ratio Rank
FULC Calmar Ratio Rank: 2222
Calmar Ratio Rank
FULC Martin Ratio Rank: 1818
Martin Ratio Rank

MELI
MELI Risk / Return Rank: 2323
Overall Rank
MELI Sharpe Ratio Rank: 2020
Sharpe Ratio Rank
MELI Sortino Ratio Rank: 2121
Sortino Ratio Rank
MELI Omega Ratio Rank: 2121
Omega Ratio Rank
MELI Calmar Ratio Rank: 2424
Calmar Ratio Rank
MELI Martin Ratio Rank: 2626
Martin Ratio Rank
The rank (0–100) uses a weighted average of the Sharpe, Sortino, Omega, Calmar, and Martin percentile ranks for the trailing 12 months. Higher means stronger historical risk-adjusted performance within the peer group.

FULC vs. MELI - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Fulcrum Therapeutics, Inc. (FULC) and MercadoLibre, Inc. (MELI). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.


FULCMELIDifference
Sharpe ratioReturn per unit of total volatility

+0.05

Sortino ratioReturn per unit of downside risk

+0.36

Omega ratioGain probability vs. loss probability

0.98

0.93

+0.04

Calmar ratioReturn relative to maximum drawdown

-0.60

-0.55

-0.05

Martin ratioReturn relative to average drawdown

-1.12

-0.90

-0.22

FULC vs. MELI - Sharpe Ratio Comparison

The current FULC Sharpe Ratio is -0.48, which is comparable to the MELI Sharpe Ratio of -0.53. The chart below compares the historical Sharpe Ratios of FULC and MELI, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.


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Drawdowns

FULC vs. MELI - Drawdown Comparison

The maximum FULC drawdown since its inception was -92.70%, roughly equal to the maximum MELI drawdown of -89.49%. Use the drawdown chart below to compare losses from any high point for FULC and MELI.


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Drawdown Indicators


FULCMELIDifference

Max Drawdown

Largest peak-to-trough decline

-92.70%

-89.49%

-3.21%

Max Drawdown (1Y)

Largest decline over 1 year

-78.49%

-38.40%

-40.09%

Max Drawdown (3Y)

Largest decline over 3 years

-79.08%

-40.82%

-38.26%

Max Drawdown (5Y)

Largest decline over 5 years

-92.70%

-68.64%

-24.06%

Max Drawdown (10Y)

Largest decline over 10 years

-69.12%

Current Drawdown

Current decline from peak

-88.44%

-28.15%

-60.29%

Average Drawdown

Average peak-to-trough decline

-63.22%

-23.65%

-39.57%

Ulcer Index

Depth and duration of drawdowns from previous peaks

41.97%

23.25%

+18.72%

Volatility

FULC vs. MELI - Volatility Comparison

Fulcrum Therapeutics, Inc. (FULC) has a higher volatility of 11.42% compared to MercadoLibre, Inc. (MELI) at 5.73%. This indicates that FULC's price experiences larger fluctuations and is considered to be riskier than MELI based on this measure. The chart below showcases a comparison of their rolling one-month volatility.


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Volatility by Period


FULCMELIDifference

Volatility (1M)

Calculated over the trailing 1-month period

11.42%

5.73%

+5.69%

Volatility (6M)

Calculated over the trailing 6-month period

85.76%

28.58%

+57.18%

Volatility (1Y)

Calculated over the trailing 1-year period

98.20%

39.80%

+58.40%

Volatility (5Y)

Calculated over the trailing 5-year period, annualized

111.00%

49.68%

+61.32%

Volatility (10Y)

Calculated over the trailing 10-year period, annualized

110.92%

48.88%

+62.04%

Dividends

FULC vs. MELI - Dividend Comparison

Neither FULC nor MELI has paid dividends to shareholders.


PositionTTM20252024202320222021202020192018201720162015
FULC
Fulcrum Therapeutics, Inc.
0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%
MELI
MercadoLibre, Inc.
0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.19%0.38%0.36%

Financials

FULC vs. MELI - Financials Comparison

This section allows you to compare key financial metrics between Fulcrum Therapeutics, Inc. and MercadoLibre, Inc.. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.


Quarterly
Annual

Total Revenue: Total amount of money received from sales and other business activities


Values in USD except per share items

Frequently Asked Questions


FULC and MELI have a correlation of 0.16, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

FULC has higher volatility (11.42%) compared to MELI (5.73%). In terms of maximum drawdown, FULC dropped -92.70% vs MELI's -89.49%.

FULC currently has the higher Sharpe Ratio (-0.48 vs -0.53), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.

Portfolio Optimizer

Find the right allocation for FULC and MELI

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