EXAI vs. ISRG

Last updated Apr 1, 2026

Compare and contrast key facts about Exscientia Ltd ADR (EXAI) and Intuitive Surgical, Inc. (ISRG).

Performance

EXAI vs. ISRG - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Exscientia Ltd ADR (EXAI) and Intuitive Surgical, Inc. (ISRG). The values are adjusted to include any dividend payments, if applicable.

EXAI vs. ISRG - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021
EXAI Exscientia Ltd ADR	0.00%	0.00%	-24.49%	20.26%	-73.03%	-27.08%
ISRG Intuitive Surgical, Inc.	-18.60%	8.51%	54.72%	27.14%	-26.15%	6.78%

Fundamentals

Total Revenue (TTM) EXAI : $17.07M ISRG : $10.06B
Gross Profit (TTM) EXAI : -$11.56M ISRG : $6.64B
EBITDA (TTM) EXAI : -$135.58M ISRG : $3.62B

Returns By Period

EXAI

• 1D: —
• 1M: —
• YTD: —
• 6M: —
• 1Y: —
• 3Y*: —
• 5Y*: —
• 10Y*: —

ISRG

• 1D: 1.81%
• 1M: -8.44%
• YTD: -18.60%
• 6M: 3.08%
• 1Y: -6.92%
• 3Y*: 21.74%
• 5Y*: 13.09%
• 10Y*: 21.20%

*Multi-year figures are annualized to reflect compound growth (CAGR)

Return for Risk

EXAI vs. ISRG — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

ISRG

ISRG Risk / Return Rank: 32
ISRG Sharpe Ratio Rank: 33
ISRG Sortino Ratio Rank: 29
ISRG Omega Ratio Rank: 29
ISRG Calmar Ratio Rank: 34
ISRG Martin Ratio Rank: 35

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

EXAI vs. ISRG - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Exscientia Ltd ADR (EXAI) and Intuitive Surgical, Inc. (ISRG). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Risk / return metrics aren't available yet — we need at least 12 months of trading data to calculate them.

Sharpe Ratios by Period

	EXAI	ISRG	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	—	-0.21	—
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	—	0.40	—
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	—	0.66	—
Sharpe Ratio (All Time) Calculated using the full available price history	—	0.49	—

Correlation

The correlation between EXAI and ISRG is 0.24, which is considered to be low. This implies their price changes are not closely related. A low correlation is generally favorable for portfolio diversification, as it helps to reduce overall risk by spreading it across multiple assets with different performance patterns.

Dividends

EXAI vs. ISRG - Dividend Comparison

Neither EXAI nor ISRG has paid dividends to shareholders.

Tickers have no history of dividend payments

Drawdowns

Drawdown Indicators

	EXAI	ISRG	Difference
Max Drawdown Largest peak-to-trough decline	—	-82.26%	—
Max Drawdown (1Y) Largest decline over 1 year	—	-24.09%	—
Max Drawdown (5Y) Largest decline over 5 years	—	-49.90%	—
Max Drawdown (10Y) Largest decline over 10 years	—	-49.90%	—
Current Drawdown Current decline from peak	—	-24.48%	—
Average Drawdown Average peak-to-trough decline	—	-21.24%	—
Ulcer Index Depth and duration of drawdowns from previous peaks	—	12.78%	—

Volatility

Volatility by Period

	EXAI	ISRG	Difference
Volatility (1M) Calculated over the trailing 1-month period	—	6.47%	—
Volatility (6M) Calculated over the trailing 6-month period	—	22.11%	—
Volatility (1Y) Calculated over the trailing 1-year period	—	33.82%	—
Volatility (5Y) Calculated over the trailing 5-year period, annualized	—	33.02%	—
Volatility (10Y) Calculated over the trailing 10-year period, annualized	—	32.10%	—

Financials