DNA vs. VOO
DNA (Ginkgo Bioworks Holdings, Inc.) is a stock, while VOO (Vanguard S&P 500 ETF) is S&P 500 fund tracking the S&P 500 Index. Over the past 5 years, DNA returned -53.86%/yr vs 13.31%/yr for VOO. At a 0.45 correlation, their price movements are largely independent.
Performance
DNA vs. VOO - Performance Comparison
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Returns By Period
In the year-to-date period, DNA achieves a -0.24% return, which is significantly lower than VOO's 10.72% return.
DNA
- 1D
- -7.89%
- 1M
- 0.97%
- 6M
- -13.47%
- YTD
- -0.24%
- 1Y
- -13.65%
- 3Y*
- -54.36%
- 5Y*
- -53.86%
- 10Y*
- —
VOO
- 1D
- -0.53%
- 1M
- 0.35%
- 6M
- 9.07%
- YTD
- 10.72%
- 1Y
- 21.71%
- 3Y*
- 20.11%
- 5Y*
- 13.31%
- 10Y*
- 15.15%
DNA vs. VOO - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | |
|---|---|---|---|---|---|---|
DNA Ginkgo Bioworks Holdings, Inc. | -0.24% | -15.38% | -85.47% | 0.00% | -79.66% | -21.68% |
VOO Vanguard S&P 500 ETF | 10.72% | 17.82% | 24.98% | 26.32% | -18.17% | 14.98% |
Correlation
The correlation between DNA and VOO is 0.39, which is low. Their price movements are largely independent, making them effective diversification partners.
| Correlation | |
|---|---|
Correlation (1Y) Calculated over the trailing 1-year period | 0.39 |
Correlation (3Y) Calculated over the trailing 3-year period | 0.43 |
Correlation (5Y) Calculated over the trailing 5-year period | 0.46 |
Correlation (All Time) Calculated using the full available price history since Apr 19, 2021 | 0.45 |
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Return for Risk
DNA vs. VOO — Risk / Return Rank
DNA
VOO
DNA vs. VOO - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for Ginkgo Bioworks Holdings, Inc. (DNA) and Vanguard S&P 500 ETF (VOO). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.
| DNA | VOO | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | -1.89 | ||
| Sortino ratioReturn per unit of downside risk | -1.93 | ||
| Omega ratioGain probability vs. loss probability | 1.06 | 1.32 | -0.26 |
| Calmar ratioReturn relative to maximum drawdown | -0.21 | 2.45 | -2.66 |
| Martin ratioReturn relative to average drawdown | -0.33 | 10.68 | -11.01 |
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Drawdowns
DNA vs. VOO - Drawdown Comparison
The maximum DNA drawdown since its inception was -99.10%, which is greater than VOO's maximum drawdown of -33.99%. Use the drawdown chart below to compare losses from any high point for DNA and VOO.
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Drawdown Indicators
| DNA | VOO | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -99.10% | -33.99% | -65.11% |
Max Drawdown (1Y)Largest decline over 1 year | -66.05% | -8.90% | -57.15% |
Max Drawdown (3Y)Largest decline over 3 years | -94.72% | -18.69% | -76.03% |
Max Drawdown (5Y)Largest decline over 5 years | -99.10% | -24.52% | -74.58% |
Max Drawdown (10Y)Largest decline over 10 years | — | -33.99% | — |
Current DrawdownCurrent decline from peak | -98.61% | -0.88% | -97.73% |
Average DrawdownAverage peak-to-trough decline | -80.19% | -3.67% | -76.52% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 40.85% | 2.04% | +38.81% |
Volatility
DNA vs. VOO - Volatility Comparison
Ginkgo Bioworks Holdings, Inc. (DNA) has a higher volatility of 22.36% compared to Vanguard S&P 500 ETF (VOO) at 3.48%. This indicates that DNA's price experiences larger fluctuations and is considered to be riskier than VOO based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| DNA | VOO | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 22.36% | 3.48% | +18.88% |
Volatility (6M)Calculated over the trailing 6-month period | 72.01% | 9.98% | +62.03% |
Volatility (1Y)Calculated over the trailing 1-year period | 95.74% | 12.52% | +83.22% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 98.37% | 16.92% | +81.45% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 96.02% | 17.99% | +78.03% |
Dividends
DNA vs. VOO - Dividend Comparison
DNA has not paid dividends to shareholders, while VOO's dividend yield for the trailing twelve months is around 1.06%.
| Position | TTM | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
DNA Ginkgo Bioworks Holdings, Inc. | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% |
VOO Vanguard S&P 500 ETF | 1.06% | 1.13% | 1.24% | 1.46% | 1.69% | 1.25% | 1.54% | 1.88% | 2.06% | 1.78% | 2.02% | 2.10% |
Frequently Asked Questions
DNA and VOO have a correlation of 0.39, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
DNA has higher volatility (22.36%) compared to VOO (3.48%). In terms of maximum drawdown, DNA dropped -99.10% vs VOO's -33.99%.
VOO currently has the higher Sharpe Ratio (1.74 vs -0.14), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.
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