DNA vs. SPY
DNA (Ginkgo Bioworks Holdings, Inc.) is a stock, while SPY (State Street SPDR S&P 500 ETF) is S&P 500 fund tracking the S&P 500 Index. Over the past 5 years, DNA returned -53.32%/yr vs 13.05%/yr for SPY. At a 0.46 correlation, their price movements are largely independent.
Performance
DNA vs. SPY - Performance Comparison
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Returns By Period
In the year-to-date period, DNA achieves a 6.62% return, which is significantly lower than SPY's 8.15% return.
DNA
- 1D
- -1.99%
- 1M
- 5.35%
- YTD
- 6.62%
- 6M
- 1.03%
- 1Y
- 3.87%
- 3Y*
- -49.30%
- 5Y*
- -53.32%
- 10Y*
- —
SPY
- 1D
- -1.45%
- 1M
- -1.36%
- YTD
- 8.15%
- 6M
- 7.20%
- 1Y
- 23.59%
- 3Y*
- 20.68%
- 5Y*
- 13.05%
- 10Y*
- 15.53%
DNA vs. SPY - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | |
|---|---|---|---|---|---|---|
DNA Ginkgo Bioworks Holdings, Inc. | 6.62% | -15.38% | -85.47% | 0.00% | -79.66% | -21.68% |
SPY State Street SPDR S&P 500 ETF | 8.15% | 17.72% | 24.89% | 26.18% | -18.18% | 14.97% |
Correlation
The correlation between DNA and SPY is 0.43, which is low. Their price movements are largely independent, making them effective diversification partners.
| Correlation | |
|---|---|
Correlation (1Y) Calculated over the trailing 1-year period | 0.43 |
Correlation (3Y) Calculated over the trailing 3-year period | 0.44 |
Correlation (5Y) Calculated over the trailing 5-year period | 0.46 |
Correlation (All Time) Calculated using the full available price history since Apr 19, 2021 | 0.46 |
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Return for Risk
DNA vs. SPY — Risk / Return Rank
DNA
SPY
DNA vs. SPY - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for Ginkgo Bioworks Holdings, Inc. (DNA) and State Street SPDR S&P 500 ETF (SPY). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.
| DNA | SPY | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | -1.86 | ||
| Sortino ratioReturn per unit of downside risk | -1.81 | ||
| Omega ratioGain probability vs. loss probability | 1.10 | 1.34 | -0.25 |
| Calmar ratioReturn relative to maximum drawdown | 0.06 | 2.67 | -2.61 |
| Martin ratioReturn relative to average drawdown | 0.10 | 11.92 | -11.82 |
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Drawdowns
DNA vs. SPY - Drawdown Comparison
The maximum DNA drawdown since its inception was -99.10%, which is greater than SPY's maximum drawdown of -55.19%. Use the drawdown chart below to compare losses from any high point for DNA and SPY.
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Drawdown Indicators
| DNA | SPY | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -99.10% | -55.19% | -43.91% |
Max Drawdown (1Y)Largest decline over 1 year | -66.05% | -8.88% | -57.17% |
Max Drawdown (3Y)Largest decline over 3 years | -94.72% | -18.76% | -75.96% |
Max Drawdown (5Y)Largest decline over 5 years | -99.10% | -24.50% | -74.60% |
Max Drawdown (10Y)Largest decline over 10 years | — | -33.72% | — |
Current DrawdownCurrent decline from peak | -98.52% | -3.17% | -95.35% |
Average DrawdownAverage peak-to-trough decline | -79.96% | -9.04% | -70.92% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 39.73% | 1.98% | +37.75% |
Volatility
DNA vs. SPY - Volatility Comparison
Ginkgo Bioworks Holdings, Inc. (DNA) has a higher volatility of 19.57% compared to State Street SPDR S&P 500 ETF (SPY) at 4.87%. This indicates that DNA's price experiences larger fluctuations and is considered to be riskier than SPY based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| DNA | SPY | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 19.57% | 4.87% | +14.70% |
Volatility (6M)Calculated over the trailing 6-month period | 70.77% | 9.85% | +60.92% |
Volatility (1Y)Calculated over the trailing 1-year period | 97.62% | 12.50% | +85.12% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 97.96% | 17.15% | +80.81% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 96.20% | 17.95% | +78.25% |
Dividends
DNA vs. SPY - Dividend Comparison
DNA has not paid dividends to shareholders, while SPY's dividend yield for the trailing twelve months is around 1.03%.
| Position | TTM | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
DNA Ginkgo Bioworks Holdings, Inc. | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% |
SPY State Street SPDR S&P 500 ETF | 1.03% | 1.07% | 1.21% | 1.40% | 1.65% | 1.20% | 1.52% | 1.75% | 2.04% | 1.80% | 2.03% | 2.06% |
Frequently Asked Questions
DNA and SPY have a correlation of 0.43, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
DNA has higher volatility (19.57%) compared to SPY (4.87%). In terms of maximum drawdown, DNA dropped -99.10% vs SPY's -55.19%.
SPY currently has the higher Sharpe Ratio (1.90 vs 0.04), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.
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