DERM vs. SGMO

Last updated Apr 2, 2026

Compare and contrast key facts about Journey Medical Corporation (DERM) and Sangamo Therapeutics, Inc. (SGMO).

Performance

DERM vs. SGMO - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Journey Medical Corporation (DERM) and Sangamo Therapeutics, Inc. (SGMO). The values are adjusted to include any dividend payments, if applicable.

DERM vs. SGMO - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021
DERM Journey Medical Corporation	-39.82%	97.19%	-32.12%	200.00%	-64.31%	-43.37%
SGMO Sangamo Therapeutics, Inc.	-38.07%	-58.82%	87.74%	-82.70%	-58.13%	-26.11%

Fundamentals

Market Cap DERM : $113.67M SGMO : $87.84M
EPS DERM : -$0.47 SGMO : -$0.41
PS Ratio DERM : 1.82 SGMO : 1.97
Total Revenue (TTM) DERM : $61.86M SGMO : $39.55M
Gross Profit (TTM) DERM : $29.23M SGMO : $25.32M
EBITDA (TTM) DERM : -$4.57M SGMO : -$117.16M

Returns By Period

The year-to-date returns for both investments are quite close, with DERM having a -39.82% return and SGMO slightly higher at -38.07%.

DERM

• 1D: -1.07%
• 1M: -42.65%
• YTD: -39.82%
• 6M: -36.00%
• 1Y: -22.28%
• 3Y*: 43.51%
• 5Y*: —
• 10Y*: —

SGMO

• 1D: 5.35%
• 1M: -39.50%
• YTD: -38.07%
• 6M: -61.44%
• 1Y: -54.38%
• 3Y*: -47.13%
• 5Y*: -53.74%
• 10Y*: -27.19%

*Multi-year figures are annualized to reflect compound growth (CAGR)

Return for Risk

DERM vs. SGMO — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

DERM

DERM Risk / Return Rank: 24
DERM Sharpe Ratio Rank: 26
DERM Sortino Ratio Rank: 28
DERM Omega Ratio Rank: 28
DERM Calmar Ratio Rank: 27
DERM Martin Ratio Rank: 11

SGMO

SGMO Risk / Return Rank: 16
SGMO Sharpe Ratio Rank: 18
SGMO Sortino Ratio Rank: 23
SGMO Omega Ratio Rank: 23
SGMO Calmar Ratio Rank: 9
SGMO Martin Ratio Rank: 8

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

DERM vs. SGMO - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Journey Medical Corporation (DERM) and Sangamo Therapeutics, Inc. (SGMO). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	DERM	SGMO	Difference
Sharpe ratio Return per unit of total volatility	-0.32	-0.51	+0.18
Sortino ratio Return per unit of downside risk	-0.01	-0.26	+0.25
Omega ratio Gain probability vs. loss probability	1.00	0.97	+0.03
Calmar ratio Return relative to maximum drawdown	-0.41	-0.87	+0.46
Martin ratio Return relative to average drawdown	-1.43	-1.54	+0.11
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

DERM vs. SGMO - Sharpe Ratio Comparison

The current DERM Sharpe Ratio is -0.32, which is higher than the SGMO Sharpe Ratio of -0.51. The chart below compares the historical Sharpe Ratios of DERM and SGMO, offering insights into how both investments have performed under varying market conditions. These values are calculated using daily returns over the previous 12 months.

Sharpe Ratios by Period

	DERM	SGMO	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	-0.32	-0.51	+0.18
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	—	-0.51	—
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	—	-0.29	—
Sharpe Ratio (All Time) Calculated using the full available price history	-0.17	-0.16	0.00

Correlation

The correlation between DERM and SGMO is 0.11, which is considered to be low. This implies their price changes are not closely related. A low correlation is generally favorable for portfolio diversification, as it helps to reduce overall risk by spreading it across multiple assets with different performance patterns.

Dividends

DERM vs. SGMO - Dividend Comparison

Neither DERM nor SGMO has paid dividends to shareholders.

Tickers have no history of dividend payments

Drawdowns

DERM vs. SGMO - Drawdown Comparison

The maximum DERM drawdown since its inception was -89.11%, smaller than the maximum SGMO drawdown of -99.50%. Use the drawdown chart below to compare losses from any high point for DERM and SGMO.

Drawdown Indicators

	DERM	SGMO	Difference
Max Drawdown Largest peak-to-trough decline	-89.11%	-99.50%	+10.39%
Max Drawdown (1Y) Largest decline over 1 year	-52.59%	-69.70%	+17.11%
Max Drawdown (5Y) Largest decline over 5 years	—	-98.05%	—
Max Drawdown (10Y) Largest decline over 10 years	—	-99.06%	—
Current Drawdown Current decline from peak	-51.16%	-99.48%	+48.32%
Average Drawdown Average peak-to-trough decline	-50.70%	-83.93%	+33.23%
Ulcer Index Depth and duration of drawdowns from previous peaks	14.96%	39.13%	-24.17%

Volatility

DERM vs. SGMO - Volatility Comparison

Journey Medical Corporation (DERM) has a higher volatility of 38.56% compared to Sangamo Therapeutics, Inc. (SGMO) at 28.34%. This indicates that DERM's price experiences larger fluctuations and is considered to be riskier than SGMO based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	DERM	SGMO	Difference
Volatility (1M) Calculated over the trailing 1-month period	38.56%	28.34%	+10.22%
Volatility (6M) Calculated over the trailing 6-month period	52.55%	78.81%	-26.26%
Volatility (1Y) Calculated over the trailing 1-year period	69.03%	108.44%	-39.41%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	91.49%	106.51%	-15.02%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	91.49%	95.01%	-3.52%

Financials