CRON vs. ATXI

Last updated Jun 5, 2026

CRON (Cronos Group Inc.) and ATXI (Avenue Therapeutics, Inc.) are both stocks. Both are in the Healthcare sector — CRON in Drug Manufacturers - Specialty & Generic, ATXI in Biotechnology. Over the past 5 years, CRON returned -20.12%/yr vs -85.31%/yr for ATXI. At a 0.10 correlation, their price movements are largely independent.

Performance

CRON vs. ATXI - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Cronos Group Inc. (CRON) and Avenue Therapeutics, Inc. (ATXI). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, CRON achieves a 6.46% return, which is significantly higher than ATXI's -48.04% return.

CRON

• 1D: 3.32%
• 1M: 6.46%
• YTD: 6.46%
• 6M: 12.45%
• 1Y: 45.08%
• 3Y*: 18.10%
• 5Y*: -20.12%
• 10Y*: —

ATXI

• 1D: 0.97%
• 1M: -32.04%
• YTD: -48.04%
• 6M: -55.82%
• 1Y: 35.92%
• 3Y*: -83.86%
• 5Y*: -85.31%
• 10Y*: —

*Multi-year figures are annualized to reflect compound growth (CAGR)

CRON vs. ATXI - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019	2018	2017
CRON Cronos Group Inc.	6.46%	30.20%	-3.35%	-17.72%	-35.20%	-43.52%	-9.52%	-26.18%	34.43%	477.19%
ATXI Avenue Therapeutics, Inc.	-48.04%	-65.99%	-83.44%	-86.12%	-91.48%	-84.74%	-38.02%	77.78%	49.17%	-56.12%

Correlation

The correlation between CRON and ATXI is -0.07, meaning there is essentially no relationship between their price movements. Each responds to its own set of market drivers, making them strong candidates for combining in a diversified portfolio.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	-0.08
Correlation (3Y) Calculated over the trailing 3-year period	0.04
Correlation (5Y) Calculated over the trailing 5-year period	0.11
Correlation (All Time) Calculated using the full available price history since Jun 28, 2017	0.10

The correlation between CRON and ATXI shifts across timeframes, from -0.07 (1 year) to 0.11 (5 years), reflecting how their relationship changes across market environments.

Fundamentals

EPS CRON : -$0.01 ATXI : -$0.55
PS Ratio CRON : 3.68 ATXI : 0.80
Total Revenue (TTM) CRON : $220.07M ATXI : $1.40M
Gross Profit (TTM) CRON : $68.18M ATXI : $0.00
EBITDA (TTM) CRON : $2.28M ATXI : -$2.06M

Return for Risk

CRON vs. ATXI — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

CRON

CRON Risk / Return Rank: 69
CRON Sharpe Ratio Rank: 71
CRON Sortino Ratio Rank: 72
CRON Omega Ratio Rank: 67
CRON Calmar Ratio Rank: 71
CRON Martin Ratio Rank: 66

ATXI

ATXI Risk / Return Rank: 61
ATXI Sharpe Ratio Rank: 47
ATXI Sortino Ratio Rank: 77
ATXI Omega Ratio Rank: 79
ATXI Calmar Ratio Rank: 52
ATXI Martin Ratio Rank: 51

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

CRON vs. ATXI - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Cronos Group Inc. (CRON) and Avenue Therapeutics, Inc. (ATXI). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	CRON	ATXI	Difference
Sharpe ratio: Return per unit of total volatility	0.98	0.15	+0.82
Sortino ratio: Return per unit of downside risk	1.79	2.10	-0.32
Omega ratio: Gain probability vs. loss probability	1.21	1.30	-0.09
Calmar ratio: Return relative to maximum drawdown	1.68	0.43	+1.25
Martin ratio: Return relative to average drawdown	2.99	0.85	+2.14
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

CRON vs. ATXI - Sharpe Ratio Comparison

The current CRON Sharpe Ratio is 0.98, which is higher than the ATXI Sharpe Ratio of 0.15. The chart below compares the historical Sharpe Ratios of CRON and ATXI, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Sharpe Ratios by Period

	CRON	ATXI	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	0.98	0.15	+0.82
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	-0.37	-0.47	+0.10
Sharpe Ratio (All Time) Calculated using the full available price history	0.44	-0.47	+0.91

Drawdowns

CRON vs. ATXI - Drawdown Comparison

The maximum CRON drawdown since its inception was -93.16%, smaller than the maximum ATXI drawdown of -100.00%. Use the drawdown chart below to compare losses from any high point for CRON and ATXI.

Drawdown Indicators

	CRON	ATXI	Difference
Max Drawdown Largest peak-to-trough decline	-93.16%	-100.00%	+6.84%
Max Drawdown (1Y) Largest decline over 1 year	-26.91%	-83.80%	+56.89%
Max Drawdown (3Y) Largest decline over 3 years	-46.36%	-99.83%	+53.47%
Max Drawdown (5Y) Largest decline over 5 years	-82.12%	-100.00%	+17.88%
Current Drawdown Current decline from peak	-88.19%	-100.00%	+11.81%
Average Drawdown Average peak-to-trough decline	-63.57%	-70.68%	+7.11%
Ulcer Index Depth and duration of drawdowns from previous peaks	15.13%	42.59%	-27.46%

Volatility

CRON vs. ATXI - Volatility Comparison

The current volatility for Cronos Group Inc. (CRON) is 12.02%, while Avenue Therapeutics, Inc. (ATXI) has a volatility of 71.21%. This indicates that CRON experiences smaller price fluctuations and is considered to be less risky than ATXI based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	CRON	ATXI	Difference
Volatility (1M) Calculated over the trailing 1-month period	12.02%	71.21%	-59.19%
Volatility (6M) Calculated over the trailing 6-month period	31.31%	165.05%	-133.74%
Volatility (1Y) Calculated over the trailing 1-year period	46.44%	233.31%	-186.87%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	53.93%	180.04%	-126.11%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	74.72%	145.53%	-70.81%

Dividends

CRON vs. ATXI - Dividend Comparison

Neither CRON nor ATXI has paid dividends to shareholders.

Tickers have no history of dividend payments

Financials

Frequently Asked Questions

Can I hold both CRON and ATXI in my portfolio?

CRON and ATXI have a correlation of -0.07, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, CRON or ATXI?

ATXI has higher volatility (71.21%) compared to CRON (12.02%). In terms of maximum drawdown, CRON dropped -93.16% vs ATXI's -100.00%.

Which has better risk-adjusted returns?

CRON currently has the higher Sharpe Ratio (0.98 vs 0.15), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.