CRL vs. ILMN
CRL (Charles River Laboratories International, Inc.) and ILMN (Illumina, Inc.) are both stocks. Both operate in the Diagnostics & Research industry within the Healthcare sector. Over the past 10 years, CRL returned 7.68%/yr vs 1.90%/yr for ILMN. At a 0.39 correlation, their price movements are largely independent.
Performance
CRL vs. ILMN - Performance Comparison
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Returns By Period
In the year-to-date period, CRL achieves a -9.83% return, which is significantly lower than ILMN's 30.32% return. Over the past 10 years, CRL has outperformed ILMN with an annualized return of 7.68%, while ILMN has yielded a comparatively lower 1.90% annualized return.
CRL
- 1D
- 2.91%
- 1M
- 4.38%
- YTD
- -9.83%
- 6M
- -2.60%
- 1Y
- 29.88%
- 3Y*
- -3.58%
- 5Y*
- -11.79%
- 10Y*
- 7.68%
ILMN
- 1D
- 5.16%
- 1M
- 22.64%
- YTD
- 30.32%
- 6M
- 33.59%
- 1Y
- 108.88%
- 3Y*
- -5.36%
- 5Y*
- -15.92%
- 10Y*
- 1.90%
CRL vs. ILMN - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | |
|---|---|---|---|---|---|---|---|---|---|---|
CRL Charles River Laboratories International, Inc. | -9.83% | 8.06% | -21.91% | 8.49% | -42.17% | 50.80% | 63.56% | 34.97% | 3.41% | 43.65% |
ILMN Illumina, Inc. | 30.32% | -1.85% | -1.34% | -31.14% | -46.85% | 2.82% | 11.53% | 10.61% | 37.27% | 70.64% |
Correlation
The correlation between CRL and ILMN is 0.53, which is moderate. They share some common price drivers but move independently often enough to provide real diversification benefit when combined.
| Correlation | |
|---|---|
Correlation (1Y) Calculated over the trailing 1-year period | 0.53 |
Correlation (3Y) Calculated over the trailing 3-year period | 0.52 |
Correlation (5Y) Calculated over the trailing 5-year period | 0.53 |
Correlation (10Y) Calculated over the trailing 10-year period | 0.53 |
Correlation (All Time) Calculated using the full available price history since Jul 31, 2000 | 0.39 |
The correlation between CRL and ILMN shifts across timeframes, from 0.39 (all time) to 0.53 (5 years), reflecting how their relationship changes across market environments.
Fundamentals
CRL:
$8.80B
ILMN:
$26.32B
CRL:
-$3.75
ILMN:
$5.48
CRL:
2.20
ILMN:
6.06
CRL:
2.99
ILMN:
8.69
CRL:
$4.03B
ILMN:
$4.39B
CRL:
$1.00B
ILMN:
$2.93B
CRL:
$737.05M
ILMN:
$1.39B
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Return for Risk
CRL vs. ILMN — Risk / Return Rank
CRL
ILMN
CRL vs. ILMN - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for Charles River Laboratories International, Inc. (CRL) and Illumina, Inc. (ILMN). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
| CRL | ILMN | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | -1.67 | ||
| Sortino ratioReturn per unit of downside risk | -2.10 | ||
| Omega ratioGain probability vs. loss probability | 1.15 | 1.39 | -0.24 |
| Calmar ratioReturn relative to maximum drawdown | 0.89 | 4.27 | -3.38 |
| Martin ratioReturn relative to average drawdown | 1.85 | 9.67 | -7.83 |
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month. | |||
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Sharpe Ratios by Period
| CRL | ILMN | Difference | |
|---|---|---|---|
Sharpe Ratio (1Y)Calculated over the trailing 1-year period | 0.67 | 2.33 | -1.67 |
Sharpe Ratio (5Y)Calculated over the trailing 5-year period | -0.28 | -0.35 | +0.07 |
Sharpe Ratio (10Y)Calculated over the trailing 10-year period | 0.20 | 0.05 | +0.16 |
Sharpe Ratio (All Time)Calculated using the full available price history | 0.24 | 0.16 | +0.08 |
Drawdowns
CRL vs. ILMN - Drawdown Comparison
The maximum CRL drawdown since its inception was -78.23%, smaller than the maximum ILMN drawdown of -96.14%. Use the drawdown chart below to compare losses from any high point for CRL and ILMN.
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Drawdown Indicators
| CRL | ILMN | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -78.23% | -96.14% | +17.91% |
Max Drawdown (1Y)Largest decline over 1 year | -33.88% | -25.66% | -8.22% |
Max Drawdown (3Y)Largest decline over 3 years | -63.52% | -65.68% | +2.16% |
Max Drawdown (5Y)Largest decline over 5 years | -78.23% | -86.23% | +8.00% |
Max Drawdown (10Y)Largest decline over 10 years | -78.23% | -86.23% | +8.00% |
Current DrawdownCurrent decline from peak | -60.75% | -66.52% | +5.77% |
Average DrawdownAverage peak-to-trough decline | -25.72% | -40.37% | +14.65% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 16.23% | 11.30% | +4.93% |
Volatility
CRL vs. ILMN - Volatility Comparison
Charles River Laboratories International, Inc. (CRL) has a higher volatility of 17.68% compared to Illumina, Inc. (ILMN) at 9.58%. This indicates that CRL's price experiences larger fluctuations and is considered to be riskier than ILMN based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| CRL | ILMN | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 17.68% | 9.58% | +8.10% |
Volatility (6M)Calculated over the trailing 6-month period | 34.98% | 29.23% | +5.75% |
Volatility (1Y)Calculated over the trailing 1-year period | 44.98% | 46.92% | -1.94% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 42.71% | 45.66% | -2.95% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 37.74% | 42.17% | -4.43% |
Dividends
CRL vs. ILMN - Dividend Comparison
Neither CRL nor ILMN has paid dividends to shareholders.
Financials
CRL vs. ILMN - Financials Comparison
This section allows you to compare key financial metrics between Charles River Laboratories International, Inc. and Illumina, Inc.. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.
Total Revenue: Total amount of money received from sales and other business activities
CRL vs. ILMN - Profitability Comparison
CRL - Gross Margin
Gross margin is calculated as gross profit divided by revenue. For the three months ending on Jun 2026, Charles River Laboratories International, Inc. reported a gross profit of 0.00 and revenue of 995.83M. Therefore, the gross margin over that period was 0.0%.
ILMN - Gross Margin
Gross margin is calculated as gross profit divided by revenue. For the three months ending on Jun 2026, Illumina, Inc. reported a gross profit of 721.00M and revenue of 1.09B. Therefore, the gross margin over that period was 66.1%.
CRL - Operating Margin
Operating margin is calculated as operating income divided by revenue. For the three months ending on Jun 2026, Charles River Laboratories International, Inc. reported an operating income of 119.90M and revenue of 995.83M, resulting in an operating margin of 12.0%.
ILMN - Operating Margin
Operating margin is calculated as operating income divided by revenue. For the three months ending on Jun 2026, Illumina, Inc. reported an operating income of 209.00M and revenue of 1.09B, resulting in an operating margin of 19.2%.
CRL - Net Margin
Net margin is calculated as net income divided by revenue. For the three months ending on Jun 2026, Charles River Laboratories International, Inc. reported a net income of -14.84M and revenue of 995.83M, resulting in a net margin of -1.5%.
ILMN - Net Margin
Net margin is calculated as net income divided by revenue. For the three months ending on Jun 2026, Illumina, Inc. reported a net income of 134.00M and revenue of 1.09B, resulting in a net margin of 12.3%.
Frequently Asked Questions
CRL and ILMN have a correlation of 0.53, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
CRL has higher volatility (17.68%) compared to ILMN (9.58%). In terms of maximum drawdown, CRL dropped -78.23% vs ILMN's -96.14%.
ILMN currently has the higher Sharpe Ratio (2.33 vs 0.67), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.
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