COLL vs. MGK

Last updated Jun 4, 2026

COLL (Collegium Pharmaceutical, Inc.) is a stock, while MGK (Vanguard Mega Cap Growth ETF) is Large Cap Growth Equities fund tracking the CRSP US Mega Cap Growth Index. Over the past 10 years, COLL returned 6.77%/yr vs 19.24%/yr for MGK. At a 0.25 correlation, their price movements are largely independent.

Performance

COLL vs. MGK - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Collegium Pharmaceutical, Inc. (COLL) and Vanguard Mega Cap Growth ETF (MGK). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, COLL achieves a -32.92% return, which is significantly lower than MGK's 10.01% return. Over the past 10 years, COLL has underperformed MGK with an annualized return of 6.77%, while MGK has yielded a comparatively higher 19.24% annualized return.

COLL

• 1D: 1.90%
• 1M: -10.18%
• YTD: -32.92%
• 6M: -35.09%
• 1Y: 6.26%
• 3Y*: 12.82%
• 5Y*: 7.33%
• 10Y*: 6.77%

MGK

• 1D: -1.13%
• 1M: 7.26%
• YTD: 10.01%
• 6M: 9.45%
• 1Y: 30.01%
• 3Y*: 26.77%
• 5Y*: 16.25%
• 10Y*: 19.24%

*Multi-year figures are annualized to reflect compound growth (CAGR)

COLL vs. MGK - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019	2018	2017
COLL Collegium Pharmaceutical, Inc.	-32.92%	61.61%	-6.92%	32.67%	24.20%	-6.74%	-2.67%	19.86%	-6.99%	18.56%
MGK Vanguard Mega Cap Growth ETF	10.01%	20.67%	32.94%	51.67%	-33.59%	28.58%	41.01%	37.38%	-2.91%	29.49%

Correlation

The correlation between COLL and MGK is 0.12, which is low. Their price movements are largely independent, making them effective diversification partners.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.12
Correlation (3Y) Calculated over the trailing 3-year period	0.16
Correlation (5Y) Calculated over the trailing 5-year period	0.22
Correlation (10Y) Calculated over the trailing 10-year period	0.24
Correlation (All Time) Calculated using the full available price history since May 8, 2015	0.25

The correlation between COLL and MGK shifts across timeframes, from 0.12 (1 year) to 0.25 (all time), reflecting how their relationship changes across market environments.

Return for Risk

COLL vs. MGK — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

COLL

COLL Risk / Return Rank: 44
COLL Sharpe Ratio Rank: 46
COLL Sortino Ratio Rank: 43
COLL Omega Ratio Rank: 42
COLL Calmar Ratio Rank: 45
COLL Martin Ratio Rank: 45

MGK

MGK Risk / Return Rank: 45
MGK Sharpe Ratio Rank: 53
MGK Sortino Ratio Rank: 50
MGK Omega Ratio Rank: 50
MGK Calmar Ratio Rank: 35
MGK Martin Ratio Rank: 38

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

COLL vs. MGK - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Collegium Pharmaceutical, Inc. (COLL) and Vanguard Mega Cap Growth ETF (MGK). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	COLL	MGK	Difference
Sharpe ratio: Return per unit of total volatility	0.16	1.86	-1.70
Sortino ratio: Return per unit of downside risk	0.54	2.53	-1.99
Omega ratio: Gain probability vs. loss probability	1.06	1.32	-0.26
Calmar ratio: Return relative to maximum drawdown	0.16	1.79	-1.63
Martin ratio: Return relative to average drawdown	0.37	6.15	-5.79
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

COLL vs. MGK - Sharpe Ratio Comparison

The current COLL Sharpe Ratio is 0.16, which is lower than the MGK Sharpe Ratio of 1.86. The chart below compares the historical Sharpe Ratios of COLL and MGK, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Sharpe Ratios by Period

	COLL	MGK	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	0.16	1.86	-1.70
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	0.18	0.72	-0.54
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	0.13	0.88	-0.76
Sharpe Ratio (All Time) Calculated using the full available price history	0.15	0.66	-0.50

Drawdowns

COLL vs. MGK - Drawdown Comparison

The maximum COLL drawdown since its inception was -73.59%, which is greater than MGK's maximum drawdown of -47.97%. Use the drawdown chart below to compare losses from any high point for COLL and MGK.

Drawdown Indicators

	COLL	MGK	Difference
Max Drawdown Largest peak-to-trough decline	-73.59%	-47.97%	-25.62%
Max Drawdown (1Y) Largest decline over 1 year	-38.84%	-16.85%	-21.99%
Max Drawdown (3Y) Largest decline over 3 years	-41.07%	-23.36%	-17.71%
Max Drawdown (5Y) Largest decline over 5 years	-43.99%	-36.01%	-7.98%
Max Drawdown (10Y) Largest decline over 10 years	-65.22%	-36.01%	-29.21%
Current Drawdown Current decline from peak	-37.68%	-1.43%	-36.25%
Average Drawdown Average peak-to-trough decline	-31.17%	-7.47%	-23.70%
Ulcer Index Depth and duration of drawdowns from previous peaks	16.99%	4.89%	+12.10%

Volatility

COLL vs. MGK - Volatility Comparison

Collegium Pharmaceutical, Inc. (COLL) has a higher volatility of 13.92% compared to Vanguard Mega Cap Growth ETF (MGK) at 4.01%. This indicates that COLL's price experiences larger fluctuations and is considered to be riskier than MGK based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	COLL	MGK	Difference
Volatility (1M) Calculated over the trailing 1-month period	13.92%	4.01%	+9.91%
Volatility (6M) Calculated over the trailing 6-month period	27.61%	12.37%	+15.24%
Volatility (1Y) Calculated over the trailing 1-year period	39.31%	16.23%	+23.08%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	40.45%	22.63%	+17.82%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	54.20%	21.88%	+32.32%

Dividends

COLL vs. MGK - Dividend Comparison

COLL has not paid dividends to shareholders, while MGK's dividend yield for the trailing twelve months is around 0.32%.

Position	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015
COLL Collegium Pharmaceutical, Inc.	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%
MGK Vanguard Mega Cap Growth ETF	0.32%	0.35%	0.43%	0.50%	0.70%	0.41%	0.65%	0.85%	1.12%	1.23%	1.53%	1.43%

Frequently Asked Questions

Can I hold both COLL and MGK in my portfolio?

COLL and MGK have a correlation of 0.12, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, COLL or MGK?

COLL has higher volatility (13.92%) compared to MGK (4.01%). In terms of maximum drawdown, COLL dropped -73.59% vs MGK's -47.97%.

Which has better risk-adjusted returns?

MGK currently has the higher Sharpe Ratio (1.86 vs 0.16), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.