CMPX vs. VGT

Last updated Jun 4, 2026

CMPX (Compass Therapeutics Inc.) is a stock, while VGT (Vanguard Information Technology ETF) is Technology Equities fund tracking the MSCI USA IMI Information Technology 25/50 Index. Over the past 5 years, CMPX returned -17.21%/yr vs 22.23%/yr for VGT. At a 0.19 correlation, their price movements are largely independent.

Performance

CMPX vs. VGT - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Compass Therapeutics Inc. (CMPX) and Vanguard Information Technology ETF (VGT). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, CMPX achieves a -60.89% return, which is significantly lower than VGT's 31.64% return.

CMPX

• 1D: 0.96%
• 1M: 8.25%
• YTD: -60.89%
• 6M: -60.23%
• 1Y: -1.87%
• 3Y*: -10.66%
• 5Y*: -17.21%
• 10Y*: —

VGT

• 1D: -1.48%
• 1M: 18.07%
• YTD: 31.64%
• 6M: 30.51%
• 1Y: 60.15%
• 3Y*: 33.48%
• 5Y*: 22.23%
• 10Y*: 25.78%

*Multi-year figures are annualized to reflect compound growth (CAGR)

CMPX vs. VGT - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021
CMPX Compass Therapeutics Inc.	-60.89%	270.34%	-7.05%	-68.99%	58.68%	-62.71%
VGT Vanguard Information Technology ETF	31.64%	21.77%	29.30%	52.66%	-29.70%	23.69%

Correlation

The correlation between CMPX and VGT is 0.22, which is low. Their price movements are largely independent, making them effective diversification partners.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.22
Correlation (3Y) Calculated over the trailing 3-year period	0.23
Correlation (5Y) Calculated over the trailing 5-year period	0.19
Correlation (All Time) Calculated using the full available price history since Apr 6, 2021	0.19

Return for Risk

CMPX vs. VGT — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

CMPX

CMPX Risk / Return Rank: 45
CMPX Sharpe Ratio Rank: 41
CMPX Sortino Ratio Rank: 49
CMPX Omega Ratio Rank: 57
CMPX Calmar Ratio Rank: 40
CMPX Martin Ratio Rank: 39

VGT

VGT Risk / Return Rank: 76
VGT Sharpe Ratio Rank: 87
VGT Sortino Ratio Rank: 79
VGT Omega Ratio Rank: 78
VGT Calmar Ratio Rank: 72
VGT Martin Ratio Rank: 64

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

CMPX vs. VGT - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Compass Therapeutics Inc. (CMPX) and Vanguard Information Technology ETF (VGT). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	CMPX	VGT	Difference
Sharpe ratio: Return per unit of total volatility	-0.02	2.95	-2.97
Sortino ratio: Return per unit of downside risk	0.79	3.63	-2.84
Omega ratio: Gain probability vs. loss probability	1.15	1.47	-0.33
Calmar ratio: Return relative to maximum drawdown	-0.03	3.69	-3.71
Martin ratio: Return relative to average drawdown	-0.07	11.77	-11.84
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

CMPX vs. VGT - Sharpe Ratio Comparison

The current CMPX Sharpe Ratio is -0.02, which is lower than the VGT Sharpe Ratio of 2.95. The chart below compares the historical Sharpe Ratios of CMPX and VGT, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Sharpe Ratios by Period

	CMPX	VGT	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	-0.02	2.95	-2.97
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	-0.20	0.89	-1.09
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	—	1.05	—
Sharpe Ratio (All Time) Calculated using the full available price history	-0.27	0.68	-0.95

Drawdowns

CMPX vs. VGT - Drawdown Comparison

The maximum CMPX drawdown since its inception was -90.91%, which is greater than VGT's maximum drawdown of -54.63%. Use the drawdown chart below to compare losses from any high point for CMPX and VGT.

Drawdown Indicators

	CMPX	VGT	Difference
Max Drawdown Largest peak-to-trough decline	-90.91%	-54.63%	-36.28%
Max Drawdown (1Y) Largest decline over 1 year	-75.04%	-16.40%	-58.64%
Max Drawdown (3Y) Largest decline over 3 years	-76.47%	-27.23%	-49.24%
Max Drawdown (5Y) Largest decline over 5 years	-85.53%	-35.07%	-50.46%
Max Drawdown (10Y) Largest decline over 10 years	—	-35.07%	—
Current Drawdown Current decline from peak	-76.14%	-1.48%	-74.66%
Average Drawdown Average peak-to-trough decline	-65.74%	-7.95%	-57.79%
Ulcer Index Depth and duration of drawdowns from previous peaks	25.45%	5.13%	+20.32%

Volatility

CMPX vs. VGT - Volatility Comparison

Compass Therapeutics Inc. (CMPX) has a higher volatility of 19.17% compared to Vanguard Information Technology ETF (VGT) at 6.39%. This indicates that CMPX's price experiences larger fluctuations and is considered to be riskier than VGT based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	CMPX	VGT	Difference
Volatility (1M) Calculated over the trailing 1-month period	19.17%	6.39%	+12.78%
Volatility (6M) Calculated over the trailing 6-month period	112.72%	16.07%	+96.65%
Volatility (1Y) Calculated over the trailing 1-year period	94.04%	20.57%	+73.47%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	87.05%	25.18%	+61.87%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	88.40%	24.60%	+63.80%

Dividends

CMPX vs. VGT - Dividend Comparison

CMPX has not paid dividends to shareholders, while VGT's dividend yield for the trailing twelve months is around 0.31%.

Position	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015
CMPX Compass Therapeutics Inc.	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%
VGT Vanguard Information Technology ETF	0.31%	0.40%	0.60%	0.65%	0.91%	0.64%	0.82%	1.11%	1.29%	0.99%	1.31%	1.28%

Frequently Asked Questions

Can I hold both CMPX and VGT in my portfolio?

CMPX and VGT have a correlation of 0.22, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, CMPX or VGT?

CMPX has higher volatility (19.17%) compared to VGT (6.39%). In terms of maximum drawdown, CMPX dropped -90.91% vs VGT's -54.63%.

Which has better risk-adjusted returns?

VGT currently has the higher Sharpe Ratio (2.95 vs -0.02), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.