CGEN vs. SGMO

Last updated Jun 5, 2026

CGEN (Compugen Ltd.) and SGMO (Sangamo Therapeutics, Inc.) are both stocks. Both operate in the Biotechnology industry within the Healthcare sector. Over the past 10 years, CGEN returned -10.56%/yr vs -30.04%/yr for SGMO. At a 0.23 correlation, their price movements are largely independent.

Performance

CGEN vs. SGMO - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Compugen Ltd. (CGEN) and Sangamo Therapeutics, Inc. (SGMO). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, CGEN achieves a 45.10% return, which is significantly higher than SGMO's -49.85% return. Over the past 10 years, CGEN has outperformed SGMO with an annualized return of -10.56%, while SGMO has yielded a comparatively lower -30.04% annualized return.

CGEN

• 1D: 1.37%
• 1M: -18.38%
• YTD: 45.10%
• 6M: 37.89%
• 1Y: 29.82%
• 3Y*: 25.62%
• 5Y*: -21.03%
• 10Y*: -10.56%

SGMO

• 1D: -2.57%
• 1M: 89.08%
• YTD: -49.85%
• 6M: -60.26%
• 1Y: -57.19%
• 3Y*: -43.37%
• 5Y*: -54.57%
• 10Y*: -30.04%

*Multi-year figures are annualized to reflect compound growth (CAGR)

CGEN vs. SGMO - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019	2018	2017
CGEN Compugen Ltd.	45.10%	-0.00%	-22.73%	176.65%	-83.36%	-64.49%	103.19%	174.65%	-13.20%	-50.98%
SGMO Sangamo Therapeutics, Inc.	-49.85%	-58.82%	87.74%	-82.70%	-58.13%	-51.94%	86.44%	-27.09%	-30.00%	437.70%

Correlation

The correlation between CGEN and SGMO is 0.21, which is low. Their price movements are largely independent, making them effective diversification partners.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.21
Correlation (3Y) Calculated over the trailing 3-year period	0.27
Correlation (5Y) Calculated over the trailing 5-year period	0.36
Correlation (10Y) Calculated over the trailing 10-year period	0.33
Correlation (All Time) Calculated using the full available price history since Aug 14, 2000	0.23

The correlation between CGEN and SGMO shifts across timeframes, from 0.21 (1 year) to 0.36 (5 years), reflecting how their relationship changes across market environments.

Fundamentals

Market Cap CGEN : $209.91M SGMO : $82.07M
EPS CGEN : $0.37 SGMO : -$0.38
PS Ratio CGEN : 2.87 SGMO : 1.96
Total Revenue (TTM) CGEN : $72.66M SGMO : $34.56M
Gross Profit (TTM) CGEN : $63.98M SGMO : $25.51M
EBITDA (TTM) CGEN : $32.73M SGMO : -$106.29M

Return for Risk

CGEN vs. SGMO — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

CGEN

CGEN Risk / Return Rank: 58
CGEN Sharpe Ratio Rank: 56
CGEN Sortino Ratio Rank: 60
CGEN Omega Ratio Rank: 55
CGEN Calmar Ratio Rank: 60
CGEN Martin Ratio Rank: 57

SGMO

SGMO Risk / Return Rank: 22
SGMO Sharpe Ratio Rank: 21
SGMO Sortino Ratio Rank: 30
SGMO Omega Ratio Rank: 30
SGMO Calmar Ratio Rank: 17
SGMO Martin Ratio Rank: 10

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

CGEN vs. SGMO - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Compugen Ltd. (CGEN) and Sangamo Therapeutics, Inc. (SGMO). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	CGEN	SGMO	Difference
Sharpe ratio: Return per unit of total volatility	0.44	-0.46	+0.89
Sortino ratio: Return per unit of downside risk	1.24	-0.04	+1.27
Omega ratio: Gain probability vs. loss probability	1.14	1.00	+0.14
Calmar ratio: Return relative to maximum drawdown	0.87	-0.66	+1.54
Martin ratio: Return relative to average drawdown	1.56	-1.35	+2.92
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

CGEN vs. SGMO - Sharpe Ratio Comparison

The current CGEN Sharpe Ratio is 0.44, which is higher than the SGMO Sharpe Ratio of -0.46. The chart below compares the historical Sharpe Ratios of CGEN and SGMO, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Sharpe Ratios by Period

	CGEN	SGMO	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	0.44	-0.46	+0.89
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	-0.19	-0.49	+0.29
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	-0.12	-0.31	+0.19
Sharpe Ratio (All Time) Calculated using the full available price history	-0.08	-0.17	+0.09

Drawdowns

CGEN vs. SGMO - Drawdown Comparison

The maximum CGEN drawdown since its inception was -97.90%, roughly equal to the maximum SGMO drawdown of -99.80%. Use the drawdown chart below to compare losses from any high point for CGEN and SGMO.

Drawdown Indicators

	CGEN	SGMO	Difference
Max Drawdown Largest peak-to-trough decline	-97.90%	-99.80%	+1.90%
Max Drawdown (1Y) Largest decline over 1 year	-34.38%	-86.32%	+51.94%
Max Drawdown (3Y) Largest decline over 3 years	-61.59%	-96.48%	+34.89%
Max Drawdown (5Y) Largest decline over 5 years	-94.00%	-99.17%	+5.17%
Max Drawdown (10Y) Largest decline over 10 years	-97.28%	-99.62%	+2.34%
Current Drawdown Current decline from peak	-88.59%	-99.58%	+10.99%
Average Drawdown Average peak-to-trough decline	-75.79%	-84.04%	+8.25%
Ulcer Index Depth and duration of drawdowns from previous peaks	19.15%	42.24%	-23.09%

Volatility

CGEN vs. SGMO - Volatility Comparison

The current volatility for Compugen Ltd. (CGEN) is 21.46%, while Sangamo Therapeutics, Inc. (SGMO) has a volatility of 44.87%. This indicates that CGEN experiences smaller price fluctuations and is considered to be less risky than SGMO based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	CGEN	SGMO	Difference
Volatility (1M) Calculated over the trailing 1-month period	21.46%	44.87%	-23.41%
Volatility (6M) Calculated over the trailing 6-month period	52.12%	116.25%	-64.13%
Volatility (1Y) Calculated over the trailing 1-year period	68.76%	125.65%	-56.89%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	108.91%	112.76%	-3.85%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	90.73%	98.47%	-7.74%

Dividends

CGEN vs. SGMO - Dividend Comparison

Neither CGEN nor SGMO has paid dividends to shareholders.

Tickers have no history of dividend payments

Financials

Frequently Asked Questions

Can I hold both CGEN and SGMO in my portfolio?

CGEN and SGMO have a correlation of 0.21, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, CGEN or SGMO?

SGMO has higher volatility (44.87%) compared to CGEN (21.46%). In terms of maximum drawdown, CGEN dropped -97.90% vs SGMO's -99.80%.

Which has better risk-adjusted returns?

CGEN currently has the higher Sharpe Ratio (0.44 vs -0.46), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.