CAH vs. AZN

Last updated Apr 2, 2026

Compare and contrast key facts about Cardinal Health, Inc. (CAH) and AstraZeneca PLC (AZN).

Performance

CAH vs. AZN - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Cardinal Health, Inc. (CAH) and AstraZeneca PLC (AZN). The values are adjusted to include any dividend payments, if applicable.

CAH vs. AZN - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019	2018	2017
CAH Cardinal Health, Inc.	3.68%	76.25%	19.01%	34.15%	54.08%	-0.40%	10.09%	18.04%	-24.50%	-12.65%
AZN AstraZeneca PLC	11.46%	43.30%	-0.62%	1.44%	19.14%	19.66%	3.12%	35.68%	13.86%	33.10%

Fundamentals

Market Cap CAH : $50.25B AZN : $313.54B
EPS CAH : $6.98 AZN : $6.55
PE Ratio CAH : 30.37 AZN : 30.64
PEG Ratio CAH : 0.72 AZN : 0.04
PS Ratio CAH : 0.21 AZN : 5.33
Total Revenue (TTM) CAH : $244.49B AZN : $58.74B
Gross Profit (TTM) CAH : $8.86B AZN : $48.11B
EBITDA (TTM) CAH : $3.23B AZN : $19.83B

Returns By Period

In the year-to-date period, CAH achieves a 3.68% return, which is significantly lower than AZN's 11.46% return. Over the past 10 years, CAH has underperformed AZN with an annualized return of 13.09%, while AZN has yielded a comparatively higher 16.92% annualized return.

CAH

• 1D: 0.58%
• 1M: -7.55%
• YTD: 3.68%
• 6M: 34.91%
• 1Y: 56.36%
• 3Y*: 43.43%
• 5Y*: 31.34%
• 10Y*: 13.09%

AZN

• 1D: 1.78%
• 1M: -1.47%
• YTD: 11.46%
• 6M: 21.46%
• 1Y: 42.12%
• 3Y*: 15.74%
• 5Y*: 17.86%
• 10Y*: 16.92%

*Multi-year figures are annualized to reflect compound growth (CAGR)

Return for Risk

CAH vs. AZN — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

CAH

CAH Risk / Return Rank: 90
CAH Sharpe Ratio Rank: 89
CAH Sortino Ratio Rank: 90
CAH Omega Ratio Rank: 90
CAH Calmar Ratio Rank: 92
CAH Martin Ratio Rank: 89

AZN

AZN Risk / Return Rank: 84
AZN Sharpe Ratio Rank: 85
AZN Sortino Ratio Rank: 82
AZN Omega Ratio Rank: 80
AZN Calmar Ratio Rank: 87
AZN Martin Ratio Rank: 85

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

CAH vs. AZN - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Cardinal Health, Inc. (CAH) and AstraZeneca PLC (AZN). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	CAH	AZN	Difference
Sharpe ratio Return per unit of total volatility	1.89	1.56	+0.33
Sortino ratio Return per unit of downside risk	2.86	2.25	+0.61
Omega ratio Gain probability vs. loss probability	1.40	1.29	+0.11
Calmar ratio Return relative to maximum drawdown	4.36	3.25	+1.11
Martin ratio Return relative to average drawdown	9.99	8.16	+1.83
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

CAH vs. AZN - Sharpe Ratio Comparison

The current CAH Sharpe Ratio is 1.89, which is comparable to the AZN Sharpe Ratio of 1.56. The chart below compares the historical Sharpe Ratios of CAH and AZN, offering insights into how both investments have performed under varying market conditions. These values are calculated using daily returns over the previous 12 months.

Sharpe Ratios by Period

	CAH	AZN	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	1.89	1.56	+0.33
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	1.25	0.75	+0.50
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	0.45	0.68	-0.23
Sharpe Ratio (All Time) Calculated using the full available price history	0.57	0.51	+0.06

Correlation

The correlation between CAH and AZN is 0.26, which is considered to be low. This implies their price changes are not closely related. A low correlation is generally favorable for portfolio diversification, as it helps to reduce overall risk by spreading it across multiple assets with different performance patterns.

Dividends

CAH vs. AZN - Dividend Comparison

CAH's dividend yield for the trailing twelve months is around 0.96%, less than AZN's 2.65% yield.

	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015
CAH Cardinal Health, Inc.	0.96%	0.99%	1.28%	1.98%	2.57%	3.80%	3.62%	3.80%	4.24%	3.00%	2.41%	1.68%
AZN AstraZeneca PLC	2.65%	1.70%	2.27%	2.15%	2.12%	2.35%	2.80%	2.81%	3.69%	3.95%	5.01%	4.06%

Drawdowns

CAH vs. AZN - Drawdown Comparison

The maximum CAH drawdown since its inception was -61.93%, which is greater than AZN's maximum drawdown of -48.94%. Use the drawdown chart below to compare losses from any high point for CAH and AZN.

Drawdown Indicators

	CAH	AZN	Difference
Max Drawdown Largest peak-to-trough decline	-61.93%	-48.94%	-12.99%
Max Drawdown (1Y) Largest decline over 1 year	-12.88%	-12.24%	-0.64%
Max Drawdown (5Y) Largest decline over 5 years	-24.69%	-27.87%	+3.18%
Max Drawdown (10Y) Largest decline over 10 years	-47.23%	-27.87%	-19.36%
Current Drawdown Current decline from peak	-7.55%	-3.70%	-3.85%
Average Drawdown Average peak-to-trough decline	-15.96%	-11.38%	-4.58%
Ulcer Index Depth and duration of drawdowns from previous peaks	5.63%	4.88%	+0.75%

Volatility

CAH vs. AZN - Volatility Comparison

Cardinal Health, Inc. (CAH) and AstraZeneca PLC (AZN) have volatilities of 6.99% and 7.15%, respectively, indicating that both stocks experience similar levels of price fluctuations. This suggests that the risk associated with both stocks, as measured by volatility, is nearly the same. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	CAH	AZN	Difference
Volatility (1M) Calculated over the trailing 1-month period	6.99%	7.15%	-0.16%
Volatility (6M) Calculated over the trailing 6-month period	22.81%	19.20%	+3.61%
Volatility (1Y) Calculated over the trailing 1-year period	30.04%	27.33%	+2.71%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	25.21%	23.85%	+1.36%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	29.25%	24.90%	+4.35%

Financials

CAH vs. AZN - Profitability Comparison

The chart below illustrates the profitability comparison between Cardinal Health, Inc. and AstraZeneca PLC over time, highlighting three key metrics: Gross Profit Margin, Operating Margin, and Net Profit Margin.

CAH - Gross Margin

Gross margin is calculated as gross profit divided by revenue. For the three months ending on Apr 2026, Cardinal Health, Inc. reported a gross profit of 2.21B and revenue of 65.44B. Therefore, the gross margin over that period was 3.4%.

AZN - Gross Margin

Gross margin is calculated as gross profit divided by revenue. For the three months ending on Apr 2026, AstraZeneca PLC reported a gross profit of 12.39B and revenue of 15.50B. Therefore, the gross margin over that period was 79.9%.

CAH - Operating Margin

Operating margin is calculated as operating income divided by revenue. For the three months ending on Apr 2026, Cardinal Health, Inc. reported an operating income of 707.00M and revenue of 65.44B, resulting in an operating margin of 1.1%.

AZN - Operating Margin

Operating margin is calculated as operating income divided by revenue. For the three months ending on Apr 2026, AstraZeneca PLC reported an operating income of 2.98B and revenue of 15.50B, resulting in an operating margin of 19.2%.

CAH - Net Margin

Net margin is calculated as net income divided by revenue. For the three months ending on Apr 2026, Cardinal Health, Inc. reported a net income of 471.00M and revenue of 65.44B, resulting in a net margin of 0.7%.

AZN - Net Margin

Net margin is calculated as net income divided by revenue. For the three months ending on Apr 2026, AstraZeneca PLC reported a net income of 2.33B and revenue of 15.50B, resulting in a net margin of 15.0%.