AVTR vs. TMO

Last updated Apr 2, 2026

Compare and contrast key facts about Avantor, Inc. (AVTR) and Thermo Fisher Scientific Inc. (TMO).

Performance

AVTR vs. TMO - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Avantor, Inc. (AVTR) and Thermo Fisher Scientific Inc. (TMO). The values are adjusted to include any dividend payments, if applicable.

AVTR vs. TMO - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019
AVTR Avantor, Inc.	-32.20%	-45.61%	-7.71%	8.25%	-49.95%	49.70%	55.10%	25.17%
TMO Thermo Fisher Scientific Inc.	-14.57%	11.78%	-1.72%	-3.36%	-17.29%	43.54%	43.72%	24.36%

Fundamentals

EPS AVTR : -$1.17 TMO : $17.77
Total Revenue (TTM) AVTR : $0.00 TMO : $44.56B
Gross Profit (TTM) AVTR : $0.00 TMO : $18.02B
EBITDA (TTM) AVTR : -$246.20M TMO : $11.35B

Returns By Period

In the year-to-date period, AVTR achieves a -32.20% return, which is significantly lower than TMO's -14.57% return.

AVTR

• 1D: -0.89%
• 1M: -11.80%
• YTD: -32.20%
• 6M: -43.16%
• 1Y: -50.82%
• 3Y*: -28.37%
• 5Y*: -23.39%
• 10Y*: —

TMO

• 1D: 0.61%
• 1M: -2.66%
• YTD: -14.57%
• 6M: -6.66%
• 1Y: 2.77%
• 3Y*: -4.68%
• 5Y*: 1.90%
• 10Y*: 13.56%

*Multi-year figures are annualized to reflect compound growth (CAGR)

Return for Risk

AVTR vs. TMO — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

AVTR

AVTR Risk / Return Rank: 5
AVTR Sharpe Ratio Rank: 6
AVTR Sortino Ratio Rank: 8
AVTR Omega Ratio Rank: 7
AVTR Calmar Ratio Rank: 4
AVTR Martin Ratio Rank: 2

TMO

TMO Risk / Return Rank: 39
TMO Sharpe Ratio Rank: 43
TMO Sortino Ratio Rank: 38
TMO Omega Ratio Rank: 37
TMO Calmar Ratio Rank: 40
TMO Martin Ratio Rank: 40

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

AVTR vs. TMO - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Avantor, Inc. (AVTR) and Thermo Fisher Scientific Inc. (TMO). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	AVTR	TMO	Difference
Sharpe ratio Return per unit of total volatility	-0.92	0.09	-1.01
Sortino ratio Return per unit of downside risk	-1.22	0.38	-1.60
Omega ratio Gain probability vs. loss probability	0.82	1.04	-0.22
Calmar ratio Return relative to maximum drawdown	-0.96	-0.01	-0.95
Martin ratio Return relative to average drawdown	-1.86	-0.02	-1.84
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

AVTR vs. TMO - Sharpe Ratio Comparison

The current AVTR Sharpe Ratio is -0.92, which is lower than the TMO Sharpe Ratio of 0.09. The chart below compares the historical Sharpe Ratios of AVTR and TMO, offering insights into how both investments have performed under varying market conditions. These values are calculated using daily returns over the previous 12 months.

Sharpe Ratios by Period

	AVTR	TMO	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	-0.92	0.09	-1.01
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	-0.60	0.07	-0.67
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	—	0.52	—
Sharpe Ratio (All Time) Calculated using the full available price history	-0.20	0.41	-0.61

Correlation

The correlation between AVTR and TMO is 0.61, which is considered to be moderate. This suggests that the two assets have some degree of positive relationship in their price movements. Moderate correlation can be acceptable for portfolio diversification, offering a balance between risk and potential returns.

Dividends

AVTR vs. TMO - Dividend Comparison

AVTR has not paid dividends to shareholders, while TMO's dividend yield for the trailing twelve months is around 0.36%.

	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015
AVTR Avantor, Inc.	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%
TMO Thermo Fisher Scientific Inc.	0.36%	0.30%	0.30%	0.26%	0.22%	0.16%	0.19%	0.23%	0.30%	0.32%	0.43%	0.42%

Drawdowns

AVTR vs. TMO - Drawdown Comparison

The maximum AVTR drawdown since its inception was -83.16%, which is greater than TMO's maximum drawdown of -71.16%. Use the drawdown chart below to compare losses from any high point for AVTR and TMO.

Drawdown Indicators

	AVTR	TMO	Difference
Max Drawdown Largest peak-to-trough decline	-83.16%	-71.16%	-12.00%
Max Drawdown (1Y) Largest decline over 1 year	-54.51%	-27.31%	-27.20%
Max Drawdown (5Y) Largest decline over 5 years	-83.16%	-40.95%	-42.21%
Max Drawdown (10Y) Largest decline over 10 years	—	-40.95%	—
Current Drawdown Current decline from peak	-82.34%	-24.98%	-57.36%
Average Drawdown Average peak-to-trough decline	-35.04%	-17.97%	-17.07%
Ulcer Index Depth and duration of drawdowns from previous peaks	27.97%	12.13%	+15.84%

Volatility

AVTR vs. TMO - Volatility Comparison

Avantor, Inc. (AVTR) has a higher volatility of 10.40% compared to Thermo Fisher Scientific Inc. (TMO) at 8.84%. This indicates that AVTR's price experiences larger fluctuations and is considered to be riskier than TMO based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	AVTR	TMO	Difference
Volatility (1M) Calculated over the trailing 1-month period	10.40%	8.84%	+1.56%
Volatility (6M) Calculated over the trailing 6-month period	40.93%	19.06%	+21.87%
Volatility (1Y) Calculated over the trailing 1-year period	55.39%	32.87%	+22.52%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	39.10%	26.59%	+12.51%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	43.17%	25.93%	+17.24%

Financials

AVTR vs. TMO - Profitability Comparison

The chart below illustrates the profitability comparison between Avantor, Inc. and Thermo Fisher Scientific Inc. over time, highlighting three key metrics: Gross Profit Margin, Operating Margin, and Net Profit Margin.

AVTR - Gross Margin

Gross margin is calculated as gross profit divided by revenue. For the three months ending on Apr 2026, Avantor, Inc. reported a gross profit of -1.62B and revenue of -4.89B. Therefore, the gross margin over that period was 33.1%.

TMO - Gross Margin

Gross margin is calculated as gross profit divided by revenue. For the three months ending on Apr 2026, Thermo Fisher Scientific Inc. reported a gross profit of 5.07B and revenue of 12.22B. Therefore, the gross margin over that period was 41.5%.

AVTR - Operating Margin

Operating margin is calculated as operating income divided by revenue. For the three months ending on Apr 2026, Avantor, Inc. reported an operating income of 126.40M and revenue of -4.89B, resulting in an operating margin of -2.6%.

TMO - Operating Margin

Operating margin is calculated as operating income divided by revenue. For the three months ending on Apr 2026, Thermo Fisher Scientific Inc. reported an operating income of 2.26B and revenue of 12.22B, resulting in an operating margin of 18.5%.

AVTR - Net Margin

Net margin is calculated as net income divided by revenue. For the three months ending on Apr 2026, Avantor, Inc. reported a net income of 52.40M and revenue of -4.89B, resulting in a net margin of -1.1%.

TMO - Net Margin

Net margin is calculated as net income divided by revenue. For the three months ending on Apr 2026, Thermo Fisher Scientific Inc. reported a net income of 1.97B and revenue of 12.22B, resulting in a net margin of 16.1%.