AVTR vs. TMO

Last updated Jun 6, 2026

AVTR (Avantor, Inc.) and TMO (Thermo Fisher Scientific Inc.) are both stocks. AVTR operates in Specialty Chemicals (Basic Materials), while TMO operates in Diagnostics & Research (Healthcare). Over the past 5 years, AVTR returned -21.79%/yr vs 1.32%/yr for TMO. A 0.61 correlation means they provide meaningful diversification when combined.

Performance

AVTR vs. TMO - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Avantor, Inc. (AVTR) and Thermo Fisher Scientific Inc. (TMO). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, AVTR achieves a -20.07% return, which is significantly lower than TMO's -18.32% return.

AVTR

• 1D: -3.78%
• 1M: 8.66%
• YTD: -20.07%
• 6M: -16.19%
• 1Y: -29.27%
• 3Y*: -22.63%
• 5Y*: -21.79%
• 10Y*: —

TMO

• 1D: -1.91%
• 1M: -0.03%
• YTD: -18.32%
• 6M: -17.31%
• 1Y: 19.12%
• 3Y*: -2.59%
• 5Y*: 1.32%
• 10Y*: 12.29%

*Multi-year figures are annualized to reflect compound growth (CAGR)

AVTR vs. TMO - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019
AVTR Avantor, Inc.	-20.07%	-45.61%	-7.71%	8.25%	-49.95%	49.70%	55.10%	25.17%
TMO Thermo Fisher Scientific Inc.	-18.32%	11.78%	-1.72%	-3.36%	-17.29%	43.54%	43.72%	24.36%

Correlation

The correlation between AVTR and TMO is 0.67, which is moderate. They share some common price drivers but move independently often enough to provide real diversification benefit when combined.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.67
Correlation (3Y) Calculated over the trailing 3-year period	0.63
Correlation (5Y) Calculated over the trailing 5-year period	0.64
Correlation (All Time) Calculated using the full available price history since May 20, 2019	0.61

The correlation between AVTR and TMO has been stable across timeframes, ranging from 0.61 to 0.67 - a consistent structural relationship.

Fundamentals

EPS AVTR : -$1.08 TMO : $18.22
PS Ratio AVTR : 0.94 TMO : 3.94
Total Revenue (TTM) AVTR : $4.97B TMO : $45.20B
Gross Profit (TTM) AVTR : $1.60B TMO : $17.81B
EBITDA (TTM) AVTR : $10.60M TMO : $11.16B

Return for Risk

AVTR vs. TMO — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

AVTR

AVTR Risk / Return Rank: 20
AVTR Sharpe Ratio Rank: 17
AVTR Sortino Ratio Rank: 19
AVTR Omega Ratio Rank: 18
AVTR Calmar Ratio Rank: 22
AVTR Martin Ratio Rank: 22

TMO

TMO Risk / Return Rank: 57
TMO Sharpe Ratio Rank: 62
TMO Sortino Ratio Rank: 57
TMO Omega Ratio Rank: 55
TMO Calmar Ratio Rank: 56
TMO Martin Ratio Rank: 56

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

AVTR vs. TMO - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Avantor, Inc. (AVTR) and Thermo Fisher Scientific Inc. (TMO). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	AVTR	TMO	Difference
Sharpe ratio: Return per unit of total volatility	-0.58	0.62	-1.20
Sortino ratio: Return per unit of downside risk	-0.52	1.12	-1.64
Omega ratio: Gain probability vs. loss probability	0.92	1.14	-0.21
Calmar ratio: Return relative to maximum drawdown	-0.56	0.61	-1.17
Martin ratio: Return relative to average drawdown	-0.96	1.37	-2.33
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

AVTR vs. TMO - Sharpe Ratio Comparison

The current AVTR Sharpe Ratio is -0.58, which is lower than the TMO Sharpe Ratio of 0.62. The chart below compares the historical Sharpe Ratios of AVTR and TMO, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Sharpe Ratios by Period

	AVTR	TMO	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	-0.58	0.62	-1.20
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	-0.55	0.05	-0.60
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	—	0.47	—
Sharpe Ratio (All Time) Calculated using the full available price history	-0.15	0.40	-0.55

Drawdowns

AVTR vs. TMO - Drawdown Comparison

The maximum AVTR drawdown since its inception was -83.16%, which is greater than TMO's maximum drawdown of -71.16%. Use the drawdown chart below to compare losses from any high point for AVTR and TMO.

Drawdown Indicators

	AVTR	TMO	Difference
Max Drawdown Largest peak-to-trough decline	-83.16%	-71.16%	-12.00%
Max Drawdown (1Y) Largest decline over 1 year	-52.50%	-31.38%	-21.12%
Max Drawdown (3Y) Largest decline over 3 years	-73.25%	-37.28%	-35.97%
Max Drawdown (5Y) Largest decline over 5 years	-83.16%	-40.95%	-42.21%
Max Drawdown (10Y) Largest decline over 10 years	—	-40.95%	—
Current Drawdown Current decline from peak	-79.19%	-28.28%	-50.91%
Average Drawdown Average peak-to-trough decline	-36.22%	-18.01%	-18.21%
Ulcer Index Depth and duration of drawdowns from previous peaks	30.48%	13.99%	+16.49%

Volatility

AVTR vs. TMO - Volatility Comparison

Avantor, Inc. (AVTR) has a higher volatility of 14.55% compared to Thermo Fisher Scientific Inc. (TMO) at 9.94%. This indicates that AVTR's price experiences larger fluctuations and is considered to be riskier than TMO based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	AVTR	TMO	Difference
Volatility (1M) Calculated over the trailing 1-month period	14.55%	9.94%	+4.61%
Volatility (6M) Calculated over the trailing 6-month period	31.08%	21.58%	+9.50%
Volatility (1Y) Calculated over the trailing 1-year period	51.04%	30.99%	+20.05%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	39.60%	27.13%	+12.47%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	43.17%	26.32%	+16.85%

Dividends

AVTR vs. TMO - Dividend Comparison

AVTR has not paid dividends to shareholders, while TMO's dividend yield for the trailing twelve months is around 0.37%.

Position	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015
AVTR Avantor, Inc.	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%
TMO Thermo Fisher Scientific Inc.	0.37%	0.30%	0.30%	0.26%	0.22%	0.16%	0.19%	0.23%	0.30%	0.32%	0.43%	0.42%

Financials

Frequently Asked Questions

Can I hold both AVTR and TMO in my portfolio?

AVTR and TMO have a correlation of 0.67, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, AVTR or TMO?

AVTR has higher volatility (14.55%) compared to TMO (9.94%). In terms of maximum drawdown, AVTR dropped -83.16% vs TMO's -71.16%.

Which has better risk-adjusted returns?

TMO currently has the higher Sharpe Ratio (0.62 vs -0.58), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.