ASND vs. JPM

Last updated Apr 1, 2026

Compare and contrast key facts about Ascendis Pharma A/S (ASND) and JPMorgan Chase & Co. (JPM).

Performance

ASND vs. JPM - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Ascendis Pharma A/S (ASND) and JPMorgan Chase & Co. (JPM). The values are adjusted to include any dividend payments, if applicable.

ASND vs. JPM - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019	2018	2017
ASND Ascendis Pharma A/S	7.26%	54.89%	9.31%	3.13%	-9.22%	-19.34%	19.88%	122.06%	56.39%	97.92%
JPM JPMorgan Chase & Co.	-8.30%	37.27%	44.29%	30.63%	-12.64%	27.75%	-5.53%	47.26%	-6.62%	26.76%

Fundamentals

Market Cap ASND : $14.04B JPM : $821.79B
EPS ASND : -$3.67 JPM : $20.42
PS Ratio ASND : 19.79 JPM : 3.20
Total Revenue (TTM) ASND : $717.81M JPM : $256.52B
Gross Profit (TTM) ASND : $619.30M JPM : $168.20B
EBITDA (TTM) ASND : -$80.69M JPM : $78.84B

Returns By Period

In the year-to-date period, ASND achieves a 7.26% return, which is significantly higher than JPM's -8.30% return. Over the past 10 years, ASND has outperformed JPM with an annualized return of 28.43%, while JPM has yielded a comparatively lower 20.45% annualized return.

ASND

• 1D: 4.75%
• 1M: -2.04%
• YTD: 7.26%
• 6M: 15.05%
• 1Y: 46.75%
• 3Y*: 28.73%
• 5Y*: 11.89%
• 10Y*: 28.43%

JPM

• 1D: 3.66%
• 1M: -2.04%
• YTD: -8.30%
• 6M: -5.87%
• 1Y: 22.38%
• 3Y*: 34.32%
• 5Y*: 16.79%
• 10Y*: 20.45%

*Multi-year figures are annualized to reflect compound growth (CAGR)

Return for Risk

ASND vs. JPM — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

ASND

ASND Risk / Return Rank: 82
ASND Sharpe Ratio Rank: 81
ASND Sortino Ratio Rank: 77
ASND Omega Ratio Rank: 72
ASND Calmar Ratio Rank: 90
ASND Martin Ratio Rank: 88

JPM

JPM Risk / Return Rank: 70
JPM Sharpe Ratio Rank: 73
JPM Sortino Ratio Rank: 64
JPM Omega Ratio Rank: 65
JPM Calmar Ratio Rank: 73
JPM Martin Ratio Rank: 74

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

ASND vs. JPM - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Ascendis Pharma A/S (ASND) and JPMorgan Chase & Co. (JPM). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	ASND	JPM	Difference
Sharpe ratio Return per unit of total volatility	1.29	0.89	+0.40
Sortino ratio Return per unit of downside risk	1.95	1.28	+0.66
Omega ratio Gain probability vs. loss probability	1.23	1.18	+0.04
Calmar ratio Return relative to maximum drawdown	3.96	1.53	+2.43
Martin ratio Return relative to average drawdown	9.47	4.16	+5.31
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

ASND vs. JPM - Sharpe Ratio Comparison

The current ASND Sharpe Ratio is 1.29, which is higher than the JPM Sharpe Ratio of 0.89. The chart below compares the historical Sharpe Ratios of ASND and JPM, offering insights into how both investments have performed under varying market conditions. These values are calculated using daily returns over the previous 12 months.

Sharpe Ratios by Period

	ASND	JPM	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	1.29	0.89	+0.40
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	0.25	0.69	-0.45
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	0.56	0.75	-0.19
Sharpe Ratio (All Time) Calculated using the full available price history	0.49	0.34	+0.16

Correlation

The correlation between ASND and JPM is 0.15, which is considered to be low. This implies their price changes are not closely related. A low correlation is generally favorable for portfolio diversification, as it helps to reduce overall risk by spreading it across multiple assets with different performance patterns.

Dividends

ASND vs. JPM - Dividend Comparison

ASND has not paid dividends to shareholders, while JPM's dividend yield for the trailing twelve months is around 1.97%.

	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015
ASND Ascendis Pharma A/S	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%
JPM JPMorgan Chase & Co.	1.97%	1.72%	1.92%	2.38%	2.98%	2.34%	2.83%	2.37%	2.54%	1.91%	2.13%	2.54%

Drawdowns

ASND vs. JPM - Drawdown Comparison

The maximum ASND drawdown since its inception was -61.72%, smaller than the maximum JPM drawdown of -76.16%. Use the drawdown chart below to compare losses from any high point for ASND and JPM.

Drawdown Indicators

	ASND	JPM	Difference
Max Drawdown Largest peak-to-trough decline	-61.72%	-76.16%	+14.44%
Max Drawdown (1Y) Largest decline over 1 year	-12.09%	-15.47%	+3.38%
Max Drawdown (5Y) Largest decline over 5 years	-60.46%	-38.77%	-21.69%
Max Drawdown (10Y) Largest decline over 10 years	-61.72%	-43.63%	-18.09%
Current Drawdown Current decline from peak	-5.52%	-12.09%	+6.57%
Average Drawdown Average peak-to-trough decline	-18.90%	-17.66%	-1.24%
Ulcer Index Depth and duration of drawdowns from previous peaks	5.06%	5.67%	-0.61%

Volatility

ASND vs. JPM - Volatility Comparison

Ascendis Pharma A/S (ASND) has a higher volatility of 9.38% compared to JPMorgan Chase & Co. (JPM) at 6.34%. This indicates that ASND's price experiences larger fluctuations and is considered to be riskier than JPM based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	ASND	JPM	Difference
Volatility (1M) Calculated over the trailing 1-month period	9.38%	6.34%	+3.04%
Volatility (6M) Calculated over the trailing 6-month period	26.45%	17.19%	+9.26%
Volatility (1Y) Calculated over the trailing 1-year period	36.54%	25.25%	+11.29%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	48.36%	24.34%	+24.02%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	51.28%	27.38%	+23.90%

Financials

ASND vs. JPM - Profitability Comparison

The chart below illustrates the profitability comparison between Ascendis Pharma A/S and JPMorgan Chase & Co. over time, highlighting three key metrics: Gross Profit Margin, Operating Margin, and Net Profit Margin.

ASND - Gross Margin

Gross margin is calculated as gross profit divided by revenue. For the three months ending on Apr 2026, Ascendis Pharma A/S reported a gross profit of 217.98M and revenue of 245.18M. Therefore, the gross margin over that period was 88.9%.

JPM - Gross Margin

Gross margin is calculated as gross profit divided by revenue. For the three months ending on Apr 2026, JPMorgan Chase & Co. reported a gross profit of 41.14B and revenue of 45.80B. Therefore, the gross margin over that period was 89.8%.

ASND - Operating Margin

Operating margin is calculated as operating income divided by revenue. For the three months ending on Apr 2026, Ascendis Pharma A/S reported an operating income of 9.80M and revenue of 245.18M, resulting in an operating margin of 4.0%.

JPM - Operating Margin

Operating margin is calculated as operating income divided by revenue. For the three months ending on Apr 2026, JPMorgan Chase & Co. reported an operating income of 17.16B and revenue of 45.80B, resulting in an operating margin of 37.5%.

ASND - Net Margin

Net margin is calculated as net income divided by revenue. For the three months ending on Apr 2026, Ascendis Pharma A/S reported a net income of -33.25M and revenue of 245.18M, resulting in a net margin of -13.6%.

JPM - Net Margin

Net margin is calculated as net income divided by revenue. For the three months ending on Apr 2026, JPMorgan Chase & Co. reported a net income of 13.03B and revenue of 45.80B, resulting in a net margin of 28.4%.