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APLS vs. ABBV
Performance
Risk-Adjusted Performance
Dividends
Drawdowns
Volatility
Financials

Correlation

The correlation between APLS and ABBV is 0.39, which is considered to be low. This implies their price changes are not closely related. A low correlation is generally favorable for portfolio diversification, as it helps to reduce overall risk by spreading it across multiple assets with different performance patterns.


Performance

APLS vs. ABBV - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Apellis Pharmaceuticals, Inc. (APLS) and AbbVie Inc. (ABBV). The values are adjusted to include any dividend payments, if applicable.

50.00%100.00%150.00%200.00%December2025FebruaryMarchAprilMay
26.94%
168.21%
APLS
ABBV

Key characteristics

Sharpe Ratio

APLS:

-1.08

ABBV:

0.73

Sortino Ratio

APLS:

-1.98

ABBV:

0.99

Omega Ratio

APLS:

0.76

ABBV:

1.15

Calmar Ratio

APLS:

-0.78

ABBV:

0.88

Martin Ratio

APLS:

-1.99

ABBV:

2.15

Ulcer Index

APLS:

31.96%

ABBV:

8.44%

Daily Std Dev

APLS:

53.71%

ABBV:

27.49%

Max Drawdown

APLS:

-81.38%

ABBV:

-45.09%

Current Drawdown

APLS:

-80.91%

ABBV:

-13.55%

Fundamentals

Market Cap

APLS:

$2.56B

ABBV:

$351.09B

EPS

APLS:

-$1.60

ABBV:

$2.34

PS Ratio

APLS:

3.27

ABBV:

6.05

PB Ratio

APLS:

11.19

ABBV:

105.59

Total Revenue (TTM)

APLS:

$609.04M

ABBV:

$57.37B

Gross Profit (TTM)

APLS:

$511.08M

ABBV:

$44.44B

EBITDA (TTM)

APLS:

-$95.69M

ABBV:

$16.33B

Returns By Period

In the year-to-date period, APLS achieves a -44.19% return, which is significantly lower than ABBV's 6.39% return.


APLS

YTD

-44.19%

1M

-4.76%

6M

-38.03%

1Y

-57.90%

5Y*

-10.82%

10Y*

N/A

ABBV

YTD

6.39%

1M

6.62%

6M

-5.71%

1Y

19.87%

5Y*

22.17%

10Y*

15.79%

*Annualized

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Risk-Adjusted Performance

APLS vs. ABBV — Risk-Adjusted Performance Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

APLS
The Risk-Adjusted Performance Rank of APLS is 33
Overall Rank
The Sharpe Ratio Rank of APLS is 33
Sharpe Ratio Rank
The Sortino Ratio Rank of APLS is 33
Sortino Ratio Rank
The Omega Ratio Rank of APLS is 44
Omega Ratio Rank
The Calmar Ratio Rank of APLS is 66
Calmar Ratio Rank
The Martin Ratio Rank of APLS is 11
Martin Ratio Rank

ABBV
The Risk-Adjusted Performance Rank of ABBV is 7474
Overall Rank
The Sharpe Ratio Rank of ABBV is 7777
Sharpe Ratio Rank
The Sortino Ratio Rank of ABBV is 6666
Sortino Ratio Rank
The Omega Ratio Rank of ABBV is 6969
Omega Ratio Rank
The Calmar Ratio Rank of ABBV is 8282
Calmar Ratio Rank
The Martin Ratio Rank of ABBV is 7474
Martin Ratio Rank
The risk-adjusted ranks indicate the investment's position relative to the market. A rank closer to 100 signifies top-performing investments, while a rank closer to 0 might suggest underperformance, based on the selected ratio. The values are calculated based on the past 12 months of returns.

APLS vs. ABBV - Risk-Adjusted Performance Comparison

This table presents a comparison of risk-adjusted performance metrics for Apellis Pharmaceuticals, Inc. (APLS) and AbbVie Inc. (ABBV). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.


The current APLS Sharpe Ratio is -1.08, which is lower than the ABBV Sharpe Ratio of 0.73. The chart below compares the historical Sharpe Ratios of APLS and ABBV, offering insights into how both investments have performed under varying market conditions. These values are calculated using daily returns over the previous 12 months.


Rolling 12-month Sharpe Ratio-1.000.001.002.003.00December2025FebruaryMarchAprilMay
-1.08
0.73
APLS
ABBV

Dividends

APLS vs. ABBV - Dividend Comparison

APLS has not paid dividends to shareholders, while ABBV's dividend yield for the trailing twelve months is around 3.44%.


TTM20242023202220212020201920182017201620152014
APLS
Apellis Pharmaceuticals, Inc.
0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%
ABBV
AbbVie Inc.
3.44%3.49%3.82%3.49%3.84%4.41%4.83%3.89%2.65%3.64%3.41%2.54%

Drawdowns

APLS vs. ABBV - Drawdown Comparison

The maximum APLS drawdown since its inception was -81.38%, which is greater than ABBV's maximum drawdown of -45.09%. Use the drawdown chart below to compare losses from any high point for APLS and ABBV. For additional features, visit the drawdowns tool.


-80.00%-60.00%-40.00%-20.00%0.00%December2025FebruaryMarchAprilMay
-80.91%
-13.55%
APLS
ABBV

Volatility

APLS vs. ABBV - Volatility Comparison

Apellis Pharmaceuticals, Inc. (APLS) has a higher volatility of 14.79% compared to AbbVie Inc. (ABBV) at 10.10%. This indicates that APLS's price experiences larger fluctuations and is considered to be riskier than ABBV based on this measure. The chart below showcases a comparison of their rolling one-month volatility.


5.00%10.00%15.00%20.00%December2025FebruaryMarchAprilMay
14.79%
10.10%
APLS
ABBV

Financials

APLS vs. ABBV - Financials Comparison

This section allows you to compare key financial metrics between Apellis Pharmaceuticals, Inc. and AbbVie Inc.. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.


Quarterly
Annual

Total Revenue: Total amount of money received from sales and other business activities


0.005.00B10.00B15.00B20212022202320242025
212.53M
13.34B
(APLS) Total Revenue
(ABBV) Total Revenue
Values in USD except per share items

APLS vs. ABBV - Profitability Comparison

The chart below illustrates the profitability comparison between Apellis Pharmaceuticals, Inc. and AbbVie Inc. over time, highlighting three key metrics: Gross Profit Margin, Operating Margin, and Net Profit Margin.

Gross Margin
Operating Margin
Net Margin
Quarterly
Annual

50.0%60.0%70.0%80.0%90.0%100.0%20212022202320242025
80.8%
83.9%
(APLS) Gross Margin
(ABBV) Gross Margin
APLS - Gross Margin

Gross margin is calculated as gross profit divided by revenue. For the three months ending on May 2025, Apellis Pharmaceuticals, Inc. reported a gross profit of 171.67M and revenue of 212.53M. Therefore, the gross margin over that period was 80.8%.

ABBV - Gross Margin

Gross margin is calculated as gross profit divided by revenue. For the three months ending on May 2025, AbbVie Inc. reported a gross profit of 11.20B and revenue of 13.34B. Therefore, the gross margin over that period was 83.9%.

APLS - Operating Margin

Operating margin is calculated as operating income divided by revenue. For the three months ending on May 2025, Apellis Pharmaceuticals, Inc. reported an operating income of -26.16M and revenue of 212.53M, resulting in an operating margin of -12.3%.

ABBV - Operating Margin

Operating margin is calculated as operating income divided by revenue. For the three months ending on May 2025, AbbVie Inc. reported an operating income of 3.73B and revenue of 13.34B, resulting in an operating margin of 28.0%.

APLS - Net Margin

Net margin is calculated as net income divided by revenue. For the three months ending on May 2025, Apellis Pharmaceuticals, Inc. reported a net income of -36.35M and revenue of 212.53M, resulting in a net margin of -17.1%.

ABBV - Net Margin

Net margin is calculated as net income divided by revenue. For the three months ending on May 2025, AbbVie Inc. reported a net income of 1.29B and revenue of 13.34B, resulting in a net margin of 9.6%.