ALGN vs. MCK

Last updated Apr 2, 2026

Compare and contrast key facts about Align Technology, Inc. (ALGN) and McKesson Corporation (MCK).

Performance

ALGN vs. MCK - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Align Technology, Inc. (ALGN) and McKesson Corporation (MCK). The values are adjusted to include any dividend payments, if applicable.

ALGN vs. MCK - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019	2018	2017
ALGN Align Technology, Inc.	10.62%	-25.11%	-23.90%	29.92%	-67.91%	22.98%	91.51%	33.24%	-5.74%	131.13%
MCK McKesson Corporation	6.43%	44.54%	23.67%	24.13%	51.82%	44.23%	27.06%	26.72%	-28.40%	11.95%

Fundamentals

Market Cap ALGN : $12.39B MCK : $107.91B
EPS ALGN : $5.68 MCK : $34.85
PE Ratio ALGN : 30.42 MCK : 25.03
PS Ratio ALGN : 3.09 MCK : 0.27
PB Ratio ALGN : 3.06 MCK : 13.93
Total Revenue (TTM) ALGN : $4.03B MCK : $397.96B
Gross Profit (TTM) ALGN : $2.71B MCK : $13.43B
EBITDA (TTM) ALGN : $685.37M MCK : $6.06B

Returns By Period

In the year-to-date period, ALGN achieves a 10.62% return, which is significantly higher than MCK's 6.43% return. Over the past 10 years, ALGN has underperformed MCK with an annualized return of 8.99%, while MCK has yielded a comparatively higher 19.59% annualized return.

ALGN

• 1D: 0.76%
• 1M: -8.62%
• YTD: 10.62%
• 6M: 35.45%
• 1Y: 9.27%
• 3Y*: -19.74%
• 5Y*: -20.53%
• 10Y*: 8.99%

MCK

• 1D: 0.80%
• 1M: -11.97%
• YTD: 6.43%
• 6M: 14.22%
• 1Y: 30.00%
• 3Y*: 35.44%
• 5Y*: 35.90%
• 10Y*: 19.59%

*Multi-year figures are annualized to reflect compound growth (CAGR)

Return for Risk

ALGN vs. MCK — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

ALGN

ALGN Risk / Return Rank: 46
ALGN Sharpe Ratio Rank: 47
ALGN Sortino Ratio Rank: 43
ALGN Omega Ratio Rank: 50
ALGN Calmar Ratio Rank: 47
ALGN Martin Ratio Rank: 45

MCK

MCK Risk / Return Rank: 75
MCK Sharpe Ratio Rank: 75
MCK Sortino Ratio Rank: 72
MCK Omega Ratio Rank: 71
MCK Calmar Ratio Rank: 79
MCK Martin Ratio Rank: 79

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

ALGN vs. MCK - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Align Technology, Inc. (ALGN) and McKesson Corporation (MCK). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	ALGN	MCK	Difference
Sharpe ratio Return per unit of total volatility	0.17	1.04	-0.87
Sortino ratio Return per unit of downside risk	0.59	1.74	-1.15
Omega ratio Gain probability vs. loss probability	1.11	1.23	-0.12
Calmar ratio Return relative to maximum drawdown	0.22	2.21	-1.99
Martin ratio Return relative to average drawdown	0.38	5.79	-5.40
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

ALGN vs. MCK - Sharpe Ratio Comparison

The current ALGN Sharpe Ratio is 0.17, which is lower than the MCK Sharpe Ratio of 1.04. The chart below compares the historical Sharpe Ratios of ALGN and MCK, offering insights into how both investments have performed under varying market conditions. These values are calculated using daily returns over the previous 12 months.

Sharpe Ratios by Period

	ALGN	MCK	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	0.17	1.04	-0.87
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	-0.42	1.49	-1.91
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	0.18	0.68	-0.50
Sharpe Ratio (All Time) Calculated using the full available price history	0.16	0.46	-0.30

Correlation

The correlation between ALGN and MCK is 0.24, which is considered to be low. This implies their price changes are not closely related. A low correlation is generally favorable for portfolio diversification, as it helps to reduce overall risk by spreading it across multiple assets with different performance patterns.

Dividends

ALGN vs. MCK - Dividend Comparison

ALGN has not paid dividends to shareholders, while MCK's dividend yield for the trailing twelve months is around 0.36%.

	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015
ALGN Align Technology, Inc.	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%
MCK McKesson Corporation	0.36%	0.37%	0.47%	0.50%	0.54%	0.72%	0.95%	1.16%	1.32%	0.80%	0.80%	0.53%

Drawdowns

ALGN vs. MCK - Drawdown Comparison

The maximum ALGN drawdown since its inception was -92.30%, which is greater than MCK's maximum drawdown of -82.84%. Use the drawdown chart below to compare losses from any high point for ALGN and MCK.

Drawdown Indicators

	ALGN	MCK	Difference
Max Drawdown Largest peak-to-trough decline	-92.30%	-82.84%	-9.46%
Max Drawdown (1Y) Largest decline over 1 year	-39.73%	-13.61%	-26.12%
Max Drawdown (5Y) Largest decline over 5 years	-82.89%	-23.91%	-58.98%
Max Drawdown (10Y) Largest decline over 10 years	-82.89%	-44.23%	-38.66%
Current Drawdown Current decline from peak	-76.34%	-12.39%	-63.95%
Average Drawdown Average peak-to-trough decline	-37.37%	-28.70%	-8.67%
Ulcer Index Depth and duration of drawdowns from previous peaks	22.84%	5.21%	+17.63%

Volatility

ALGN vs. MCK - Volatility Comparison

Align Technology, Inc. (ALGN) has a higher volatility of 13.28% compared to McKesson Corporation (MCK) at 7.23%. This indicates that ALGN's price experiences larger fluctuations and is considered to be riskier than MCK based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	ALGN	MCK	Difference
Volatility (1M) Calculated over the trailing 1-month period	13.28%	7.23%	+6.05%
Volatility (6M) Calculated over the trailing 6-month period	27.12%	21.84%	+5.28%
Volatility (1Y) Calculated over the trailing 1-year period	54.36%	29.06%	+25.30%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	49.37%	24.14%	+25.23%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	48.79%	28.87%	+19.92%

Financials

ALGN vs. MCK - Profitability Comparison

The chart below illustrates the profitability comparison between Align Technology, Inc. and McKesson Corporation over time, highlighting three key metrics: Gross Profit Margin, Operating Margin, and Net Profit Margin.

ALGN - Gross Margin

Gross margin is calculated as gross profit divided by revenue. For the three months ending on Apr 2026, Align Technology, Inc. reported a gross profit of 683.59M and revenue of 1.05B. Therefore, the gross margin over that period was 65.3%.

MCK - Gross Margin

Gross margin is calculated as gross profit divided by revenue. For the three months ending on Apr 2026, McKesson Corporation reported a gross profit of 3.69B and revenue of 106.16B. Therefore, the gross margin over that period was 3.5%.

ALGN - Operating Margin

Operating margin is calculated as operating income divided by revenue. For the three months ending on Apr 2026, Align Technology, Inc. reported an operating income of 155.32M and revenue of 1.05B, resulting in an operating margin of 14.8%.

MCK - Operating Margin

Operating margin is calculated as operating income divided by revenue. For the three months ending on Apr 2026, McKesson Corporation reported an operating income of 1.62B and revenue of 106.16B, resulting in an operating margin of 1.5%.

ALGN - Net Margin

Net margin is calculated as net income divided by revenue. For the three months ending on Apr 2026, Align Technology, Inc. reported a net income of 135.76M and revenue of 1.05B, resulting in a net margin of 13.0%.

MCK - Net Margin

Net margin is calculated as net income divided by revenue. For the three months ending on Apr 2026, McKesson Corporation reported a net income of 1.19B and revenue of 106.16B, resulting in a net margin of 1.1%.