AGIO vs. MO
AGIO (Agios Pharmaceuticals, Inc.) and MO (Altria Group, Inc.) are both stocks. AGIO operates in Biotechnology (Healthcare), while MO operates in Tobacco (Consumer Defensive). Over the past 10 years, AGIO returned -3.95%/yr vs 7.21%/yr for MO. Their 0.09 correlation means their historical movements had little consistent relationship.
Performance
AGIO vs. MO - Performance Comparison
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Returns By Period
In the year-to-date period, AGIO achieves a 10.29% return, which is significantly lower than MO's 22.29% return. Over the past 10 years, AGIO has underperformed MO with an annualized return of -3.95%, while MO has yielded a comparatively higher 7.21% annualized return.
AGIO
- 1D
- -8.34%
- 1M
- -20.12%
- 6M
- 9.40%
- YTD
- 10.29%
- 1Y
- -14.23%
- 3Y*
- 3.87%
- 5Y*
- -8.99%
- 10Y*
- -3.95%
- ALL TIME*
- 0.27%
MO
- 1D
- 0.57%
- 1M
- -6.02%
- 6M
- 13.75%
- YTD
- 22.29%
- 1Y
- 18.10%
- 3Y*
- 23.87%
- 5Y*
- 15.92%
- 10Y*
- 7.21%
- ALL TIME*
- 17.80%
Liquidity Comparison
| Position | Avg. Volume Value (2W) | Avg. Volume Value (1M) | Avg. Volume Value (3M) |
|---|---|---|---|
| $51.87M | $46.01M | $36.85M | |
| $637.73M | $559.86M | $594.92M |
AGIO vs. MO - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | |
|---|---|---|---|---|---|---|---|---|---|---|
AGIO Agios Pharmaceuticals, Inc. | 10.29% | -17.16% | 47.55% | -20.69% | -14.57% | -24.14% | -9.26% | 3.56% | -19.35% | 37.00% |
MO Altria Group, Inc. | 22.29% | 18.17% | 40.76% | -3.70% | 4.37% | 24.18% | -10.21% | 7.87% | -27.14% | 9.45% |
Correlation
The correlation between AGIO and MO is 0.04, meaning there was essentially no consistent relationship between their historical price movements. Each responded to its own set of market drivers.
| Correlation | |
|---|---|
Correlation (1Y) Focuses on recent behavior, but can change the most. | 0.04 |
Correlation (3Y) Balances recent behavior with more history. | 0.10 |
Correlation (5Y) Shows whether the relationship held over a longer period. | 0.13 |
Correlation (10Y) Provides a long-term view across more market conditions. | 0.11 |
Correlation (All Time) Calculated using the full available price history since Jul 24, 2013 | 0.09 |
Fundamentals
AGIO:
$1.79B
MO:
$114.07B
AGIO:
-$7.01
MO:
$4.76
AGIO:
17.92
MO:
5.24
AGIO:
$98.34M
MO:
$21.87B
AGIO:
$86.46M
MO:
$15.52B
AGIO:
-$418.15M
MO:
$11.75B
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Return for Risk
AGIO vs. MO — Risk / Return Rank
AGIO
MO
AGIO vs. MO - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for Agios Pharmaceuticals, Inc. (AGIO) and Altria Group, Inc. (MO). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.
| AGIO | MO | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | -0.97 | ||
| Sortino ratioReturn per unit of downside risk | -0.81 | ||
| Omega ratioGain probability vs. loss probability | 1.05 | 1.15 | -0.10 |
| Calmar ratioReturn relative to maximum drawdown | -0.38 | 1.09 | -1.47 |
| Martin ratioReturn relative to average drawdown | -0.66 | 2.71 | -3.37 |
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Drawdowns
AGIO vs. MO - Drawdown Comparison
The maximum AGIO drawdown since its inception was -87.36%, which is greater than MO's maximum drawdown of -65.43%. Use the drawdown chart below to compare losses from any high point for AGIO and MO.
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Drawdown Indicators
| AGIO | MO | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -87.36% | -65.43% | -21.93% |
Max Drawdown (1Y)Largest decline over 1 year | -50.89% | -16.40% | -34.49% |
Max Drawdown (3Y)Largest decline over 3 years | -63.76% | -16.40% | -47.36% |
Max Drawdown (5Y)Largest decline over 5 years | -65.73% | -25.83% | -39.90% |
Max Drawdown (10Y)Largest decline over 10 years | -82.86% | -53.69% | -29.17% |
Current DrawdownCurrent decline from peak | -77.76% | -8.80% | -68.96% |
Average DrawdownAverage peak-to-trough decline | -59.00% | -11.90% | -47.10% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 29.43% | 6.59% | +22.84% |
Volatility
AGIO vs. MO - Volatility Comparison
Agios Pharmaceuticals, Inc. (AGIO) has a higher volatility of 22.65% compared to Altria Group, Inc. (MO) at 12.13%. This indicates that AGIO's price experiences larger fluctuations and is considered to be riskier than MO based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| AGIO | MO | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 22.65% | 12.13% | +10.52% |
Volatility (6M)Calculated over the trailing 6-month period | 45.99% | 20.12% | +25.87% |
Volatility (1Y)Calculated over the trailing 1-year period | 77.63% | 24.97% | +52.66% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 59.62% | 21.27% | +38.35% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 56.97% | 23.29% | +33.68% |
Dividends
AGIO vs. MO - Dividend Comparison
AGIO has not paid dividends to shareholders, while MO's dividend yield for the trailing twelve months is around 6.21%.
| Position | TTM | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
AGIO Agios Pharmaceuticals, Inc. | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% |
MO Altria Group, Inc. | 6.21% | 7.21% | 7.65% | 9.52% | 8.05% | 7.43% | 8.29% | 6.57% | 6.07% | 3.56% | 3.48% | 3.73% |
Financials
AGIO vs. MO - Financials Comparison
This section allows you to compare key financial metrics between Agios Pharmaceuticals, Inc. and Altria Group, Inc.. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.
Total Revenue: Total amount of money received from sales and other business activities
Frequently Asked Questions
AGIO and MO have a correlation of 0.04, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
AGIO has higher volatility (22.65%) compared to MO (12.13%). In terms of maximum drawdown, AGIO dropped -87.36% vs MO's -65.43%.
MO currently has the higher Sharpe Ratio (0.72 vs -0.25), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.
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