ADVM vs. LEGN

Last updated Jun 4, 2026

ADVM (Adverum Biotechnologies, Inc.) and LEGN (Legend Biotech Corporation) are both stocks. Both operate in the Biotechnology industry within the Healthcare sector. Over the past 5 years, ADVM returned -33.53%/yr vs -1.43%/yr for LEGN. At a 0.19 correlation, their price movements are largely independent.

Performance

ADVM vs. LEGN - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Adverum Biotechnologies, Inc. (ADVM) and Legend Biotech Corporation (LEGN). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

ADVM

• 1D: 0.00%
• 1M: 0.00%
• YTD: 0.00%
• 6M: 4.56%
• 1Y: 73.71%
• 3Y*: -28.84%
• 5Y*: -33.53%
• 10Y*: -20.75%

LEGN

• 1D: -0.83%
• 1M: 35.77%
• YTD: 65.50%
• 6M: 29.66%
• 1Y: 26.56%
• 3Y*: -17.20%
• 5Y*: -1.43%
• 10Y*: —

*Multi-year figures are annualized to reflect compound growth (CAGR)

ADVM vs. LEGN - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020
ADVM Adverum Biotechnologies, Inc.	0.00%	-6.64%	-37.96%	29.91%	-67.07%	-83.76%	-52.17%
LEGN Legend Biotech Corporation	65.50%	-33.19%	-45.92%	20.53%	7.10%	65.52%	-23.89%

Correlation

The correlation between ADVM and LEGN is 0.10, which is low. Their price movements are largely independent, making them effective diversification partners.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.10
Correlation (3Y) Calculated over the trailing 3-year period	0.14
Correlation (5Y) Calculated over the trailing 5-year period	0.18
Correlation (All Time) Calculated using the full available price history since Jun 8, 2020	0.19

Fundamentals

Market Cap ADVM : $102.40M LEGN : $3.33B
EPS ADVM : -$9.19 LEGN : -$1.55
Total Revenue (TTM) ADVM : $0.00 LEGN : $1.14B
Gross Profit (TTM) ADVM : -$465.00K LEGN : $611.63M
EBITDA (TTM) ADVM : -$205.45M LEGN : -$186.04M

Return for Risk

ADVM vs. LEGN — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

ADVM

ADVM Risk / Return Rank: 82
ADVM Sharpe Ratio Rank: 80
ADVM Sortino Ratio Rank: 82
ADVM Omega Ratio Rank: 85
ADVM Calmar Ratio Rank: 85
ADVM Martin Ratio Rank: 77

LEGN

LEGN Risk / Return Rank: 54
LEGN Sharpe Ratio Rank: 54
LEGN Sortino Ratio Rank: 62
LEGN Omega Ratio Rank: 58
LEGN Calmar Ratio Rank: 50
LEGN Martin Ratio Rank: 49

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

ADVM vs. LEGN - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Adverum Biotechnologies, Inc. (ADVM) and Legend Biotech Corporation (LEGN). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	ADVM	LEGN	Difference
Sharpe ratio Return per unit of total volatility	1.38	0.39	+1.00
Sortino ratio Return per unit of downside risk	2.46	1.34	+1.12
Omega ratio Gain probability vs. loss probability	1.36	1.15	+0.21
Calmar ratio Return relative to maximum drawdown	3.40	0.43	+2.98
Martin ratio Return relative to average drawdown	5.48	0.67	+4.80
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

ADVM vs. LEGN - Sharpe Ratio Comparison

The current ADVM Sharpe Ratio is 1.38, which is higher than the LEGN Sharpe Ratio of 0.39. The chart below compares the historical Sharpe Ratios of ADVM and LEGN, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Sharpe Ratios by Period

	ADVM	LEGN	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	1.38	0.39	+1.00
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	-0.45	-0.03	-0.42
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	-0.26	—	—
Sharpe Ratio (All Time) Calculated using the full available price history	-0.31	-0.01	-0.30

Drawdowns

ADVM vs. LEGN - Drawdown Comparison

The maximum ADVM drawdown since its inception was -99.20%, which is greater than LEGN's maximum drawdown of -78.24%. Use the drawdown chart below to compare losses from any high point for ADVM and LEGN.

Drawdown Indicators

	ADVM	LEGN	Difference
Max Drawdown Largest peak-to-trough decline	-99.20%	-78.24%	-20.96%
Max Drawdown (1Y) Largest decline over 1 year	-27.61%	-62.43%	+34.82%
Max Drawdown (3Y) Largest decline over 3 years	-92.70%	-78.24%	-14.46%
Max Drawdown (5Y) Largest decline over 5 years	-94.63%	-78.24%	-16.39%
Max Drawdown (10Y) Largest decline over 10 years	-99.20%	—	—
Current Drawdown Current decline from peak	-98.30%	-52.97%	-45.33%
Average Drawdown Average peak-to-trough decline	-69.72%	-31.34%	-38.38%
Ulcer Index Depth and duration of drawdowns from previous peaks	25.54%	39.47%	-13.93%

Volatility

ADVM vs. LEGN - Volatility Comparison

The current volatility for Adverum Biotechnologies, Inc. (ADVM) is 0.00%, while Legend Biotech Corporation (LEGN) has a volatility of 40.69%. This indicates that ADVM experiences smaller price fluctuations and is considered to be less risky than LEGN based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	ADVM	LEGN	Difference
Volatility (1M) Calculated over the trailing 1-month period	0.00%	40.69%	-40.69%
Volatility (6M) Calculated over the trailing 6-month period	26.29%	57.77%	-31.48%
Volatility (1Y) Calculated over the trailing 1-year period	68.06%	69.00%	-0.94%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	76.85%	56.04%	+20.81%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	81.33%	55.65%	+25.68%

Dividends

ADVM vs. LEGN - Dividend Comparison

Neither ADVM nor LEGN has paid dividends to shareholders.

Tickers have no history of dividend payments

Financials

Frequently Asked Questions

Can I hold both ADVM and LEGN in my portfolio?

ADVM and LEGN have a correlation of 0.10, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, ADVM or LEGN?

LEGN has higher volatility (40.69%) compared to ADVM (0.00%). In terms of maximum drawdown, ADVM dropped -99.20% vs LEGN's -78.24%.

Which has better risk-adjusted returns?

ADVM currently has the higher Sharpe Ratio (1.38 vs 0.39), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.