- ISIN
- US45674E1091
- CUSIP
- 45674E109
- Sector
- Healthcare
- Industry
- Biotechnology
- IPO Date
- Jul 30, 2021
Highlights
- Market Cap
- $29.98M
- Enterprise Value
- $11.42M
- EPS (TTM)
- -$2.34
- Gross Profit (TTM)
- -$1.17M
- EBITDA (TTM)
- -$17.46M
- Year Range
- $1.17 - $4.17
- Target Price
- $4.00
- ROA (TTM)
- -72.26%
- ROE (TTM)
- -83.32%
Share Price Chart
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Performance
INAB Performance Chart
IN8bio, Inc. (INAB) is down 34.2% since the beginning of the year. At $2 per share, INAB is trading 63.1% below its 52-week high of $4.
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Returns By Period
IN8bio, Inc. (INAB) has returned -34.19% so far this year and -58.50% over the past 12 months.
IN8bio, Inc.
- 1D
- -1.28%
- 1M
- -4.35%
- YTD
- -34.19%
- 6M
- -12.00%
- 1Y
- -58.50%
- 3Y*
- -74.65%
- 5Y*
- —
- 10Y*
- —
Benchmark (S&P 500 Index)
- 1D
- -0.74%
- 1M
- 4.90%
- YTD
- 10.35%
- 6M
- 10.28%
- 1Y
- 26.52%
- 3Y*
- 20.83%
- 5Y*
- 12.30%
- 10Y*
- 13.66%
INAB Monthly Returns History
Based on dividend-adjusted daily data since Jul 30, 2021, INAB's average daily return is -0.11%, while the average monthly return is -5.51%.
Historically, 36% of months were positive and 64% were negative. The best month was May 2023 with a return of +108.2%, while the worst month was Jun 2025 at -53.0%. The longest winning streak lasted 3 consecutive months, and the longest losing streak was 6 months.
On a daily basis, INAB closed higher 41% of trading days. The best single day was Apr 24, 2023 with a return of +185.7%, while the worst single day was Apr 25, 2023 at -36.3%.
| Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec | Total | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2026 | -15.81% | -13.71% | -12.94% | -0.68% | 27.21% | -17.65% | -34.19% | ||||||
| 2025 | -0.54% | 5.20% | -38.31% | 1.81% | -12.31% | -52.99% | 1.91% | 3.76% | -1.81% | -10.14% | 1.54% | 18.18% | -69.67% |
| 2024 | -5.80% | -14.62% | 6.31% | -13.56% | 16.67% | -28.87% | -0.78% | -37.33% | -48.71% | 3.78% | 8.85% | -15.67% | -81.36% |
| 2023 | -0.61% | -33.36% | -15.03% | 12.31% | 108.22% | -49.34% | -23.38% | -11.02% | -0.95% | -5.78% | -15.30% | 66.27% | -40.26% |
| 2022 | -23.23% | 24.63% | -20.71% | -27.93% | -7.91% | 2.26% | 12.39% | 1.97% | -22.01% | -3.47% | -10.77% | 32.76% | -47.38% |
| 2021 | -32.00% | 0.74% | 10.80% | -22.79% | -25.09% | -56.10% |
Benchmark Metrics
IN8bio, Inc. has an annualized alpha of -34.40%, beta of 1.04, and R2 of 0.02 versus S&P 500 Index. Calculated based on daily prices since August 02, 2021.
- This stock participated in 185.34% of S&P 500 Index downside but only -108.19% of its upside - more exposed to losses than it benefited from rallies.
- R2 of 0.02 means this stock moves largely independently of S&P 500 Index - capture ratios reflect limited market correlation rather than active downside protection. Consider using a more representative benchmark.
- Alpha
- -34.40%
- Beta
- 1.04
- R²
- 0.02
- Upside Capture
- -108.19%
- Downside Capture
- 185.34%
Return for Risk
Risk / Return Rank
INAB ranks 14 for risk / return — in the bottom 14% of stocks on our site. This means you're taking on significantly more risk than the returns justify. Consider whether the potential upside is worth the volatility, or explore alternatives with better risk / return profiles.
Return / Risk — by metrics
The table below present risk-adjusted performance metrics for IN8bio, Inc. (INAB) and compare them to S&P 500 Index.
| INAB | Benchmark | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | -2.91 | ||
| Sortino ratioReturn per unit of downside risk | -3.90 | ||
| Omega ratioGain probability vs. loss probability | 0.90 | 1.41 | -0.50 |
| Calmar ratioReturn relative to maximum drawdown | -0.83 | 2.93 | -3.75 |
| Martin ratioReturn relative to average drawdown | -1.09 | 13.52 | -14.62 |
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month. | |||
Dividends
Dividend History
Drawdowns
Drawdowns Chart
The Drawdowns chart displays portfolio losses from any high point along the way. Drawdowns are calculated considering price movements and all distributions paid, if any.
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Worst Drawdowns
The table below displays the maximum drawdowns of the IN8bio, Inc.. A maximum drawdown is a measure of risk, indicating the largest reduction in portfolio value due to a series of losing trades.
The maximum drawdown for the IN8bio, Inc. was 99.60%, occurring on Dec 19, 2025. The portfolio has not yet recovered.
The current IN8bio, Inc. drawdown is 99.49%.
Related event | Drawdown | Fall | Recovery | Underwater |
|---|---|---|---|---|
2025 bear market2025 | -99.60%Dec 2025 | 4y 4mo | — | 4y 10moAug 2021 - now |
Drawdown Indicators
| INAB | Benchmark | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -99.60% | -56.78% | -42.82% |
Max Drawdown (1Y)Largest decline over 1 year | -70.98% | -9.10% | -61.88% |
Max Drawdown (3Y)Largest decline over 3 years | -98.52% | -18.90% | -79.62% |
Max Drawdown (5Y)Largest decline over 5 years | — | -25.43% | — |
Max Drawdown (10Y)Largest decline over 10 years | — | -33.92% | — |
Current DrawdownCurrent decline from peak | -99.49% | -0.74% | -98.75% |
Average DrawdownAverage peak-to-trough decline | -82.93% | -10.72% | -72.21% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 53.48% | 1.97% | +51.51% |
Volatility
Volatility Chart
The chart below shows the rolling one-month volatility.
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Financials
Financial Performance
The chart below illustrates the trends in the financial health of IN8bio, Inc. over time, highlighting three key metrics: Total Revenue, Earnings Before Interest and Taxes (EBIT), and Net Income.
Valuation
The Valuation section provides an overview of how IN8bio, Inc. is priced in the market compared to other companies in the Biotechnology industry. It includes key financial ratios that help investors assess whether the stock is undervalued or overvalued.
PB Ratio
The chart illustrates the Price-to-Book (P/B) ratio for INAB in comparison with other companies in the Biotechnology industry. Currently, INAB has a P/B value of 1.3. This P/B ratio is in line with the industry average, suggesting the stock is valued fairly in relation to its book value.
Income Statement
| TTM | |
|---|---|
Revenue | — |
Total Revenue | — |
Cost Of Revenue | — |
Gross Profit | — |
Operating Expenses | — |
Selling, General & Admin Expenses | — |
R&D Expenses | — |
Depreciation And Amortization | — |
Total Operating Expenses | — |
Income | — |
Income Before Tax | — |
Operating Income | — |
EBITDA | — |
EBIT | — |
Earnings From Continuing Operations | — |
Net Income | — |
Income Tax Expense | — |
Other Non-Operating Income (Expenses) | — |
Extraordinary Items | — |
Discontinued Operations | — |
Effect Of Accounting Charges | — |
Non Recurring | — |
Minority Interest | — |
Other Items | — |
Interest Income | — |
Interest Expense | — |
Net Interest Income | — |
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