- Sector
- Healthcare
- Industry
- Biotechnology
- IPO Date
- Mar 25, 2022
Highlights
- Market Cap
- $192.69M
- Enterprise Value
- $139.20M
- EPS (TTM)
- -$1.10
- EBITDA (TTM)
- -$37.12M
- Year Range
- $1.00 - $6.91
- Target Price
- $7.75
- ROA (TTM)
- -39.49%
- ROE (TTM)
- -42.26%
- Avg. Volume (1M)
- 212K
- Avg. Volume Value (1M)
- $1.00M
Share Price Chart
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Performance
ANTX Performance Chart
AN2 Therapeutics Inc (ANTX) is up 369.3% since the beginning of the year. At $5 per share, ANTX is trading 22.6% below its 52-week high of $7.
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Returns By Period
AN2 Therapeutics Inc (ANTX) has returned 369.30% so far this year and 404.72% over the past 12 months.
AN2 Therapeutics Inc
- 1D
- 0.38%
- 1M
- 21.04%
- 6M
- 373.45%
- YTD
- 369.30%
- 1Y
- 404.72%
- 3Y*
- -13.27%
- 5Y*
- —
- 10Y*
- —
- ALL TIME*
- -23.18%
Benchmark (S&P 500 Index)
- 1D
- 0.70%
- 1M
- 0.09%
- 6M
- 7.94%
- YTD
- 9.41%
- 1Y
- 20.07%
- 3Y*
- 17.84%
- 5Y*
- 11.25%
- 10Y*
- 13.26%
- ALL TIME*
- 8.09%
ANTX Monthly Returns History
Based on dividend-adjusted daily data since Mar 25, 2022, ANTX's average daily return is +0.18%, while the average monthly return is +4.75%. At this rate, an investment would double in approximately 1.2 years.
Historically, 43% of months were positive and 57% were negative. The best month was Mar 2026 with a return of +210.9%, while the worst month was Feb 2024 at -84.6%. The longest winning streak lasted 3 consecutive months, and the longest losing streak was 4 months.
On a daily basis, ANTX closed higher 46% of trading days. The best single day was Mar 9, 2026 with a return of +84.2%, while the worst single day was Feb 12, 2024 at -74.5%.
| Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec | Total | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2026 | -0.88% | -2.65% | 210.91% | 33.04% | -4.84% | 11.78% | 10.54% | 369.30% | |||||
| 2025 | -17.39% | -0.00% | 19.30% | -8.82% | -14.52% | 0.00% | 0.00% | 3.77% | 15.45% | -3.15% | -11.38% | 4.59% | -17.39% |
| 2024 | -5.81% | -84.56% | 9.06% | -26.15% | -17.08% | 8.04% | 18.60% | -55.69% | -5.31% | 0.93% | 54.63% | -17.37% | -93.27% |
| 2023 | 27.60% | -7.24% | -12.50% | -20.47% | -28.54% | 51.52% | -4.47% | 85.22% | 6.91% | -10.32% | 21.84% | 16.62% | 115.01% |
| 2022 | -10.56% | 3.72% | -4.03% | -48.33% | 10.45% | 100.23% | 1.40% | -17.03% | -30.86% | -4.41% | -43.44% |
Benchmark Metrics
AN2 Therapeutics Inc has an annualized alpha of 41.29%, beta of 0.80, and R2 of 0.01 versus S&P 500 Index. Calculated based on daily prices since March 25, 2022.
- This stock tended to rise when S&P 500 Index fell (downside capture of -411.79%), but participation in market rallies was also limited (-108.98%) - a profile typical of counter-cyclical assets.
- R2 of 0.01 means this stock moves largely independently of S&P 500 Index - capture ratios reflect limited market correlation rather than active downside protection. Consider using a more representative benchmark.
- Alpha
- 41.29%
- Beta
- 0.80
- R²
- 0.01
- Upside Capture
- -108.98%
- Downside Capture
- -411.79%
Return for Risk
Risk / Return Rank
ANTX ranks 98 for risk / return — above 98% of stocks peers on PortfoliosLab. Its historical combined result is among the stronger results in the peer group.
Risk / Return Metrics
The table below present risk-adjusted performance metrics for AN2 Therapeutics Inc (ANTX) and compare them to S&P 500 Index.
Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.
| ANTX | Benchmark | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | +1.70 | ||
| Sortino ratioReturn per unit of downside risk | +3.43 | ||
| Omega ratioGain probability vs. loss probability | 1.65 | 1.25 | +0.39 |
| Calmar ratioReturn relative to maximum drawdown | 8.95 | 2.00 | +6.94 |
| Martin ratioReturn relative to average drawdown | 23.25 | 8.49 | +14.76 |
Dividends
Dividend History
Drawdowns
Drawdowns Chart
The Drawdowns chart displays portfolio losses from any high point along the way. Drawdowns are calculated considering price movements and all distributions paid, if any.
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Worst Drawdowns
The table below displays the maximum drawdowns of the AN2 Therapeutics Inc. A maximum drawdown is a measure of risk, indicating the largest reduction in portfolio value due to a series of losing trades.
The maximum drawdown for the AN2 Therapeutics Inc was 95.60%, occurring on Aug 16, 2024. The portfolio has not yet recovered.
The current AN2 Therapeutics Inc drawdown is 76.00%.
Drawdown | Fall | Recovery | Underwater | Related event |
|---|---|---|---|---|
-95.60%Aug 2024 | 2y 1d | — | 3y 11moAug 2022 - now | — |
-59.56%Aug 2022 | 2mo 24d | 11d | 3mo 5dMay 2022 - Aug 2022 | Bear market2022 |
-18.93%Apr 2022 | 17d | 23d | 1mo 10dMar 2022 - May 2022 | Bear market2022 |
Drawdown Indicators
| ANTX | Benchmark | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -95.60% | -56.78% | -38.82% |
Max Drawdown (1Y)Largest decline over 1 year | -45.60% | -9.10% | -36.50% |
Max Drawdown (3Y)Largest decline over 3 years | -95.45% | -18.90% | -76.55% |
Max Drawdown (5Y)Largest decline over 5 years | — | -25.43% | — |
Max Drawdown (10Y)Largest decline over 10 years | — | -33.92% | — |
Current DrawdownCurrent decline from peak | -76.00% | -1.58% | -74.42% |
Average DrawdownAverage peak-to-trough decline | -69.33% | -10.70% | -58.63% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 17.51% | 2.14% | +15.37% |
Volatility
Volatility Chart
The chart below shows the rolling one-month volatility.
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Financials
Financial Performance
The chart below illustrates the trends in the financial health of AN2 Therapeutics Inc over time, highlighting three key metrics: Total Revenue, Earnings Before Interest and Taxes (EBIT), and Net Income.
Valuation
The Valuation section provides an overview of how AN2 Therapeutics Inc is priced in the market compared to other companies in the Biotechnology industry. It includes key financial ratios that help investors assess whether the stock is undervalued or overvalued.
PB Ratio
The chart illustrates the Price-to-Book (P/B) ratio for ANTX in comparison with other companies in the Biotechnology industry. Currently, ANTX has a P/B value of 2.2. This P/B ratio is in line with the industry average, suggesting the stock is valued fairly in relation to its book value.
Income Statement
| TTM | |
|---|---|
Revenue | |
Total Revenue | — |
Cost Of Revenue | — |
Gross Profit | — |
Operating Expenses | |
Selling, General & Admin Expenses | — |
R&D Expenses | — |
Depreciation And Amortization | — |
Total Operating Expenses | — |
Income | |
Income Before Tax | — |
Operating Income | — |
EBITDA | — |
EBIT | — |
Earnings From Continuing Operations | — |
Net Income | — |
Income Tax Expense | — |
Other Non-Operating Income (Expenses) | — |
Extraordinary Items | — |
Discontinued Operations | — |
Effect Of Accounting Charges | — |
Non Recurring | — |
Minority Interest | — |
Other Items | — |
Interest Income | — |
Interest Expense | — |
Net Interest Income | — |
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