MCK vs. VKTX

Last updated Jun 9, 2026

MCK (McKesson Corporation) and VKTX (Viking Therapeutics, Inc.) are both stocks. Both are in the Healthcare sector — MCK in Medical Distribution, VKTX in Biotechnology. Over the past 10 years, MCK returned 16.13%/yr vs 36.31%/yr for VKTX. At a 0.11 correlation, their price movements are largely independent.

Performance

MCK vs. VKTX - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in McKesson Corporation (MCK) and Viking Therapeutics, Inc. (VKTX). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, MCK achieves a -6.36% return, which is significantly higher than VKTX's -16.88% return. Over the past 10 years, MCK has underperformed VKTX with an annualized return of 16.13%, while VKTX has yielded a comparatively higher 36.31% annualized return.

MCK

• 1D: -1.16%
• 1M: 4.27%
• YTD: -6.36%
• 6M: -3.74%
• 1Y: 7.98%
• 3Y*: 25.42%
• 5Y*: 32.82%
• 10Y*: 16.13%

VKTX

• 1D: 2.78%
• 1M: -6.67%
• YTD: -16.88%
• 6M: -23.01%
• 1Y: 5.07%
• 3Y*: 6.41%
• 5Y*: 39.22%
• 10Y*: 36.31%

*Multi-year figures are annualized to reflect compound growth (CAGR)

MCK vs. VKTX - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019	2018	2017
MCK McKesson Corporation	-6.36%	44.54%	23.67%	24.13%	51.82%	44.23%	27.06%	26.72%	-28.40%	11.95%
VKTX Viking Therapeutics, Inc.	-16.88%	-12.57%	116.23%	97.98%	104.35%	-18.29%	-29.80%	4.84%	88.42%	241.18%

Correlation

The correlation between MCK and VKTX is -0.02, meaning there is essentially no relationship between their price movements. Each responds to its own set of market drivers, making them strong candidates for combining in a diversified portfolio.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	-0.02
Correlation (3Y) Calculated over the trailing 3-year period	0.01
Correlation (5Y) Calculated over the trailing 5-year period	0.06
Correlation (10Y) Calculated over the trailing 10-year period	0.13
Correlation (All Time) Calculated using the full available price history since Apr 30, 2015	0.11

The correlation between MCK and VKTX shifts across timeframes, from -0.02 (1 year) to 0.13 (10 years), reflecting how their relationship changes across market environments.

Fundamentals

Market Cap MCK : $94.07B VKTX : $3.38B
EPS MCK : $38.38 VKTX : -$4.16
PB Ratio MCK : 13.60 VKTX : 6.73
Total Revenue (TTM) MCK : $403.43B VKTX : $0.00
Gross Profit (TTM) MCK : $14.55B VKTX : -$208.00K
EBITDA (TTM) MCK : $6.91B VKTX : -$501.77M

Return for Risk

MCK vs. VKTX — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

MCK

MCK Risk / Return Rank: 49
MCK Sharpe Ratio Rank: 52
MCK Sortino Ratio Rank: 47
MCK Omega Ratio Rank: 47
MCK Calmar Ratio Rank: 49
MCK Martin Ratio Rank: 51

VKTX

VKTX Risk / Return Rank: 46
VKTX Sharpe Ratio Rank: 44
VKTX Sortino Ratio Rank: 47
VKTX Omega Ratio Rank: 49
VKTX Calmar Ratio Rank: 45
VKTX Martin Ratio Rank: 45

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

MCK vs. VKTX - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for McKesson Corporation (MCK) and Viking Therapeutics, Inc. (VKTX). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	MCK	VKTX	Difference
Sharpe ratio: Return per unit of total volatility	0.28	0.07	+0.21
Sortino ratio: Return per unit of downside risk	0.65	0.63	+0.01
Omega ratio: Gain probability vs. loss probability	1.08	1.10	-0.01
Calmar ratio: Return relative to maximum drawdown	0.29	0.11	+0.18
Martin ratio: Return relative to average drawdown	0.79	0.23	+0.57
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

MCK vs. VKTX - Sharpe Ratio Comparison

The current MCK Sharpe Ratio is 0.28, which is higher than the VKTX Sharpe Ratio of 0.07. The chart below compares the historical Sharpe Ratios of MCK and VKTX, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Sharpe Ratios by Period

	MCK	VKTX	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	0.28	0.07	+0.21
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	1.36	0.39	+0.98
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	0.56	0.38	+0.19
Sharpe Ratio (All Time) Calculated using the full available price history	0.44	0.11	+0.33

Drawdowns

MCK vs. VKTX - Drawdown Comparison

The maximum MCK drawdown since its inception was -82.84%, smaller than the maximum VKTX drawdown of -90.41%. Use the drawdown chart below to compare losses from any high point for MCK and VKTX.

Drawdown Indicators

	MCK	VKTX	Difference
Max Drawdown Largest peak-to-trough decline	-82.84%	-90.41%	+7.57%
Max Drawdown (1Y) Largest decline over 1 year	-27.17%	-45.14%	+17.97%
Max Drawdown (3Y) Largest decline over 3 years	-27.17%	-78.86%	+51.69%
Max Drawdown (5Y) Largest decline over 5 years	-27.17%	-78.86%	+51.69%
Max Drawdown (10Y) Largest decline over 10 years	-44.23%	-89.26%	+45.03%
Current Drawdown Current decline from peak	-22.92%	-69.06%	+46.14%
Average Drawdown Average peak-to-trough decline	-28.65%	-60.02%	+31.37%
Ulcer Index Depth and duration of drawdowns from previous peaks	10.06%	22.54%	-12.48%

Volatility

MCK vs. VKTX - Volatility Comparison

The current volatility for McKesson Corporation (MCK) is 6.94%, while Viking Therapeutics, Inc. (VKTX) has a volatility of 14.20%. This indicates that MCK experiences smaller price fluctuations and is considered to be less risky than VKTX based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	MCK	VKTX	Difference
Volatility (1M) Calculated over the trailing 1-month period	6.94%	14.20%	-7.26%
Volatility (6M) Calculated over the trailing 6-month period	22.76%	40.45%	-17.69%
Volatility (1Y) Calculated over the trailing 1-year period	29.16%	74.12%	-44.96%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	24.20%	101.63%	-77.43%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	28.82%	97.07%	-68.25%

Dividends

MCK vs. VKTX - Dividend Comparison

MCK's dividend yield for the trailing twelve months is around 0.43%, while VKTX has not paid dividends to shareholders.

Position	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015
MCK McKesson Corporation	0.43%	0.37%	0.47%	0.50%	0.54%	0.72%	0.95%	1.16%	1.32%	0.80%	0.80%	0.53%
VKTX Viking Therapeutics, Inc.	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%

Financials

Frequently Asked Questions

Can I hold both MCK and VKTX in my portfolio?

MCK and VKTX have a correlation of -0.02, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, MCK or VKTX?

VKTX has higher volatility (14.20%) compared to MCK (6.94%). In terms of maximum drawdown, MCK dropped -82.84% vs VKTX's -90.41%.

Which has better risk-adjusted returns?

MCK currently has the higher Sharpe Ratio (0.28 vs 0.07), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.