MCK vs. AZN
MCK (McKesson Corporation) and AZN (AstraZeneca PLC) are both stocks. Both are in the Healthcare sector — MCK in Medical Distribution, AZN in Drug Manufacturers - General. Over the past 10 years, MCK returned 16.13%/yr vs 15.85%/yr for AZN. At a 0.24 correlation, their price movements are largely independent.
Performance
MCK vs. AZN - Performance Comparison
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Returns By Period
In the year-to-date period, MCK achieves a -6.36% return, which is significantly lower than AZN's 0.81% return. Both investments have delivered pretty close results over the past 10 years, with MCK having a 16.13% annualized return and AZN not far behind at 15.85%.
MCK
- 1D
- -1.16%
- 1M
- 4.27%
- YTD
- -6.36%
- 6M
- -3.74%
- 1Y
- 7.98%
- 3Y*
- 25.42%
- 5Y*
- 32.82%
- 10Y*
- 16.13%
AZN
- 1D
- -2.37%
- 1M
- -0.71%
- YTD
- 0.81%
- 6M
- 1.53%
- 1Y
- 28.04%
- 3Y*
- 9.54%
- 5Y*
- 12.08%
- 10Y*
- 15.85%
MCK vs. AZN - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | |
|---|---|---|---|---|---|---|---|---|---|---|
MCK McKesson Corporation | -6.36% | 44.54% | 23.67% | 24.13% | 51.82% | 44.23% | 27.06% | 26.72% | -28.40% | 11.95% |
AZN AstraZeneca PLC | 0.81% | 43.30% | -0.62% | 1.44% | 19.14% | 19.66% | 3.12% | 35.68% | 13.86% | 33.10% |
Correlation
The correlation between MCK and AZN is 0.26, which is low. Their price movements are largely independent, making them effective diversification partners.
| Correlation | |
|---|---|
Correlation (1Y) Calculated over the trailing 1-year period | 0.26 |
Correlation (3Y) Calculated over the trailing 3-year period | 0.16 |
Correlation (5Y) Calculated over the trailing 5-year period | 0.22 |
Correlation (10Y) Calculated over the trailing 10-year period | 0.24 |
Correlation (All Time) Calculated using the full available price history since Nov 16, 1994 | 0.24 |
Fundamentals
MCK:
$94.07B
AZN:
$283.40B
MCK:
$38.38
AZN:
$6.66
MCK:
19.97
AZN:
27.27
MCK:
0.27
AZN:
0.04
MCK:
0.24
AZN:
4.69
MCK:
13.60
AZN:
5.99
MCK:
$403.43B
AZN:
$60.44B
MCK:
$14.55B
AZN:
$49.37B
MCK:
$6.91B
AZN:
$20.47B
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Return for Risk
MCK vs. AZN — Risk / Return Rank
MCK
AZN
MCK vs. AZN - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for McKesson Corporation (MCK) and AstraZeneca PLC (AZN). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
| MCK | AZN | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | -0.83 | ||
| Sortino ratioReturn per unit of downside risk | -1.19 | ||
| Omega ratioGain probability vs. loss probability | 1.08 | 1.21 | -0.13 |
| Calmar ratioReturn relative to maximum drawdown | 0.29 | 1.83 | -1.54 |
| Martin ratioReturn relative to average drawdown | 0.79 | 4.90 | -4.11 |
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month. | |||
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Sharpe Ratios by Period
| MCK | AZN | Difference | |
|---|---|---|---|
Sharpe Ratio (1Y)Calculated over the trailing 1-year period | 0.28 | 1.11 | -0.83 |
Sharpe Ratio (5Y)Calculated over the trailing 5-year period | 1.36 | 0.51 | +0.86 |
Sharpe Ratio (10Y)Calculated over the trailing 10-year period | 0.56 | 0.64 | -0.08 |
Sharpe Ratio (All Time)Calculated using the full available price history | 0.44 | 0.49 | -0.05 |
Drawdowns
MCK vs. AZN - Drawdown Comparison
The maximum MCK drawdown since its inception was -82.84%, which is greater than AZN's maximum drawdown of -48.94%. Use the drawdown chart below to compare losses from any high point for MCK and AZN.
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Drawdown Indicators
| MCK | AZN | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -82.84% | -48.94% | -33.90% |
Max Drawdown (1Y)Largest decline over 1 year | -27.17% | -15.43% | -11.74% |
Max Drawdown (3Y)Largest decline over 3 years | -27.17% | -27.87% | +0.70% |
Max Drawdown (5Y)Largest decline over 5 years | -27.17% | -27.87% | +0.70% |
Max Drawdown (10Y)Largest decline over 10 years | -44.23% | -27.87% | -16.36% |
Current DrawdownCurrent decline from peak | -22.92% | -12.90% | -10.02% |
Average DrawdownAverage peak-to-trough decline | -28.65% | -11.37% | -17.28% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 10.06% | 5.75% | +4.31% |
Volatility
MCK vs. AZN - Volatility Comparison
The current volatility for McKesson Corporation (MCK) is 6.94%, while AstraZeneca PLC (AZN) has a volatility of 7.42%. This indicates that MCK experiences smaller price fluctuations and is considered to be less risky than AZN based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| MCK | AZN | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 6.94% | 7.42% | -0.48% |
Volatility (6M)Calculated over the trailing 6-month period | 22.76% | 17.47% | +5.29% |
Volatility (1Y)Calculated over the trailing 1-year period | 29.16% | 25.55% | +3.61% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 24.20% | 24.02% | +0.18% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 28.82% | 24.94% | +3.88% |
Dividends
MCK vs. AZN - Dividend Comparison
MCK's dividend yield for the trailing twelve months is around 0.43%, less than AZN's 2.93% yield.
| Position | TTM | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
AZN AstraZeneca PLC | 2.93% | 1.70% | 2.27% | 2.15% | 2.12% | 2.35% | 2.80% | 2.81% | 3.69% | 3.95% | 5.01% | 4.06% |
MCK McKesson Corporation | 0.43% | 0.37% | 0.47% | 0.50% | 0.54% | 0.72% | 0.95% | 1.16% | 1.32% | 0.80% | 0.80% | 0.53% |
Financials
MCK vs. AZN - Financials Comparison
This section allows you to compare key financial metrics between McKesson Corporation and AstraZeneca PLC. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.
Total Revenue: Total amount of money received from sales and other business activities
MCK vs. AZN - Profitability Comparison
MCK - Gross Margin
Gross margin is calculated as gross profit divided by revenue. For the three months ending on Jun 2026, McKesson Corporation reported a gross profit of 4.04B and revenue of 96.30B. Therefore, the gross margin over that period was 4.2%.
AZN - Gross Margin
Gross margin is calculated as gross profit divided by revenue. For the three months ending on Jun 2026, AstraZeneca PLC reported a gross profit of 12.61B and revenue of 15.29B. Therefore, the gross margin over that period was 82.5%.
MCK - Operating Margin
Operating margin is calculated as operating income divided by revenue. For the three months ending on Jun 2026, McKesson Corporation reported an operating income of 2.09B and revenue of 96.30B, resulting in an operating margin of 2.2%.
AZN - Operating Margin
Operating margin is calculated as operating income divided by revenue. For the three months ending on Jun 2026, AstraZeneca PLC reported an operating income of 4.25B and revenue of 15.29B, resulting in an operating margin of 27.8%.
MCK - Net Margin
Net margin is calculated as net income divided by revenue. For the three months ending on Jun 2026, McKesson Corporation reported a net income of 1.68B and revenue of 96.30B, resulting in a net margin of 1.8%.
AZN - Net Margin
Net margin is calculated as net income divided by revenue. For the three months ending on Jun 2026, AstraZeneca PLC reported a net income of 3.08B and revenue of 15.29B, resulting in a net margin of 20.2%.
Frequently Asked Questions
MCK and AZN have a correlation of 0.26, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
AZN has higher volatility (7.42%) compared to MCK (6.94%). In terms of maximum drawdown, MCK dropped -82.84% vs AZN's -48.94%.
AZN currently has the higher Sharpe Ratio (1.11 vs 0.28), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.
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