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LLY vs. AZN
Performance
Return for Risk
Drawdowns
Volatility
Dividends
Financials

Performance

LLY vs. AZN - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Eli Lilly and Company (LLY) and AstraZeneca PLC (AZN). The values are adjusted to include any dividend payments, if applicable.

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Returns By Period

In the year-to-date period, LLY achieves a 7.29% return, which is significantly higher than AZN's 0.81% return. Over the past 10 years, LLY has outperformed AZN with an annualized return of 33.71%, while AZN has yielded a comparatively lower 15.85% annualized return.


LLY

1D
1.57%
1M
21.37%
YTD
7.29%
6M
15.58%
1Y
50.32%
3Y*
38.07%
5Y*
39.75%
10Y*
33.71%

AZN

1D
-2.37%
1M
-0.71%
YTD
0.81%
6M
1.53%
1Y
28.04%
3Y*
9.54%
5Y*
12.08%
10Y*
15.85%
*Multi-year figures are annualized to reflect compound growth (CAGR)

LLY vs. AZN - Yearly Performance Comparison


2026 (YTD)202520242023202220212020201920182017
LLY
Eli Lilly and Company
7.29%40.25%33.30%60.91%34.26%66.08%31.04%16.14%40.45%17.83%
AZN
AstraZeneca PLC
0.81%43.30%-0.62%1.44%19.14%19.66%3.12%35.68%13.86%33.10%

Correlation

The correlation between LLY and AZN is 0.39, which is low. Their price movements are largely independent, making them effective diversification partners.


Correlation
Correlation (1Y)
Calculated over the trailing 1-year period

0.39

Correlation (3Y)
Calculated over the trailing 3-year period

0.33

Correlation (5Y)
Calculated over the trailing 5-year period

0.35

Correlation (10Y)
Calculated over the trailing 10-year period

0.37

Correlation (All Time)
Calculated using the full available price history since May 18, 1993

0.34

Fundamentals

Market Cap

LLY:

$1.03T

AZN:

$283.40B

EPS

LLY:

$28.14

AZN:

$6.66

PE Ratio

LLY:

40.83

AZN:

27.27

PEG Ratio

LLY:

0.82

AZN:

0.04

PS Ratio

LLY:

14.28

AZN:

4.69

PB Ratio

LLY:

33.00

AZN:

5.99

Total Revenue (TTM)

LLY:

$72.25B

AZN:

$60.44B

Gross Profit (TTM)

LLY:

$59.75B

AZN:

$49.37B

EBITDA (TTM)

LLY:

$32.97B

AZN:

$20.47B

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Return for Risk

LLY vs. AZN — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

LLY
LLY Risk / Return Rank: 7777
Overall Rank
LLY Sharpe Ratio Rank: 7979
Sharpe Ratio Rank
LLY Sortino Ratio Rank: 7474
Sortino Ratio Rank
LLY Omega Ratio Rank: 7676
Omega Ratio Rank
LLY Calmar Ratio Rank: 7777
Calmar Ratio Rank
LLY Martin Ratio Rank: 7777
Martin Ratio Rank

AZN
AZN Risk / Return Rank: 7373
Overall Rank
AZN Sharpe Ratio Rank: 7575
Sharpe Ratio Rank
AZN Sortino Ratio Rank: 7373
Sortino Ratio Rank
AZN Omega Ratio Rank: 6969
Omega Ratio Rank
AZN Calmar Ratio Rank: 7474
Calmar Ratio Rank
AZN Martin Ratio Rank: 7676
Martin Ratio Rank
The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

LLY vs. AZN - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Eli Lilly and Company (LLY) and AstraZeneca PLC (AZN). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.


LLYAZNDifference
Sharpe ratioReturn per unit of total volatility

+0.22

Sortino ratioReturn per unit of downside risk

+0.07

Omega ratioGain probability vs. loss probability

1.26

1.21

+0.05

Calmar ratioReturn relative to maximum drawdown

2.14

1.83

+0.31

Martin ratioReturn relative to average drawdown

5.32

4.90

+0.42

LLY vs. AZN - Sharpe Ratio Comparison

The current LLY Sharpe Ratio is 1.33, which is comparable to the AZN Sharpe Ratio of 1.11. The chart below compares the historical Sharpe Ratios of LLY and AZN, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.


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Sharpe Ratios by Period


LLYAZNDifference

Sharpe Ratio (1Y)

Calculated over the trailing 1-year period

1.33

1.11

+0.22

Sharpe Ratio (5Y)

Calculated over the trailing 5-year period

1.23

0.51

+0.72

Sharpe Ratio (10Y)

Calculated over the trailing 10-year period

1.12

0.64

+0.48

Sharpe Ratio (All Time)

Calculated using the full available price history

0.58

0.49

+0.09

Drawdowns

LLY vs. AZN - Drawdown Comparison

The maximum LLY drawdown since its inception was -68.24%, which is greater than AZN's maximum drawdown of -48.94%. Use the drawdown chart below to compare losses from any high point for LLY and AZN.


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Drawdown Indicators


LLYAZNDifference

Max Drawdown

Largest peak-to-trough decline

-68.24%

-48.94%

-19.30%

Max Drawdown (1Y)

Largest decline over 1 year

-23.64%

-15.43%

-8.21%

Max Drawdown (3Y)

Largest decline over 3 years

-34.48%

-27.87%

-6.61%

Max Drawdown (5Y)

Largest decline over 5 years

-34.48%

-27.87%

-6.61%

Max Drawdown (10Y)

Largest decline over 10 years

-34.48%

-27.87%

-6.61%

Current Drawdown

Current decline from peak

0.00%

-12.90%

+12.90%

Average Drawdown

Average peak-to-trough decline

-19.22%

-11.37%

-7.85%

Ulcer Index

Depth and duration of drawdowns from previous peaks

9.49%

5.75%

+3.74%

Volatility

LLY vs. AZN - Volatility Comparison

Eli Lilly and Company (LLY) has a higher volatility of 9.55% compared to AstraZeneca PLC (AZN) at 7.42%. This indicates that LLY's price experiences larger fluctuations and is considered to be riskier than AZN based on this measure. The chart below showcases a comparison of their rolling one-month volatility.


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Volatility by Period


LLYAZNDifference

Volatility (1M)

Calculated over the trailing 1-month period

9.55%

7.42%

+2.13%

Volatility (6M)

Calculated over the trailing 6-month period

27.05%

17.47%

+9.58%

Volatility (1Y)

Calculated over the trailing 1-year period

38.16%

25.55%

+12.61%

Volatility (5Y)

Calculated over the trailing 5-year period, annualized

32.54%

24.02%

+8.52%

Volatility (10Y)

Calculated over the trailing 10-year period, annualized

30.18%

24.94%

+5.24%

Dividends

LLY vs. AZN - Dividend Comparison

LLY's dividend yield for the trailing twelve months is around 0.56%, less than AZN's 2.93% yield.


PositionTTM20252024202320222021202020192018201720162015
AZN
AstraZeneca PLC
2.93%1.70%2.27%2.15%2.12%2.35%2.80%2.81%3.69%3.95%5.01%4.06%
LLY
Eli Lilly and Company
0.56%0.56%0.67%0.78%1.07%1.23%1.75%1.96%1.94%2.46%2.77%2.37%

Financials

LLY vs. AZN - Financials Comparison

This section allows you to compare key financial metrics between Eli Lilly and Company and AstraZeneca PLC. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.


Quarterly
Annual

Total Revenue: Total amount of money received from sales and other business activities


6.00B8.00B10.00B12.00B14.00B16.00B18.00B20.00B20222023202420252026
19.80B
15.29B
(LLY) Total Revenue
(AZN) Total Revenue
Values in USD except per share items

LLY vs. AZN - Profitability Comparison

The chart below illustrates the profitability comparison between Eli Lilly and Company and AstraZeneca PLC over time, highlighting three key metrics: Gross Profit Margin, Operating Margin, and Net Profit Margin.

Gross Margin
Operating Margin
Net Margin
Quarterly
Annual

60.0%65.0%70.0%75.0%80.0%85.0%20222023202420252026
79.0%
82.5%
Portfolio components
LLY - Gross Margin

Gross margin is calculated as gross profit divided by revenue. For the three months ending on Jun 2026, Eli Lilly and Company reported a gross profit of 15.64B and revenue of 19.80B. Therefore, the gross margin over that period was 79.0%.

AZN - Gross Margin

Gross margin is calculated as gross profit divided by revenue. For the three months ending on Jun 2026, AstraZeneca PLC reported a gross profit of 12.61B and revenue of 15.29B. Therefore, the gross margin over that period was 82.5%.

LLY - Operating Margin

Operating margin is calculated as operating income divided by revenue. For the three months ending on Jun 2026, Eli Lilly and Company reported an operating income of 9.19B and revenue of 19.80B, resulting in an operating margin of 46.4%.

AZN - Operating Margin

Operating margin is calculated as operating income divided by revenue. For the three months ending on Jun 2026, AstraZeneca PLC reported an operating income of 4.25B and revenue of 15.29B, resulting in an operating margin of 27.8%.

LLY - Net Margin

Net margin is calculated as net income divided by revenue. For the three months ending on Jun 2026, Eli Lilly and Company reported a net income of 7.40B and revenue of 19.80B, resulting in a net margin of 37.4%.

AZN - Net Margin

Net margin is calculated as net income divided by revenue. For the three months ending on Jun 2026, AstraZeneca PLC reported a net income of 3.08B and revenue of 15.29B, resulting in a net margin of 20.2%.


Frequently Asked Questions


LLY and AZN have a correlation of 0.39, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

LLY has higher volatility (9.55%) compared to AZN (7.42%). In terms of maximum drawdown, LLY dropped -68.24% vs AZN's -48.94%.

LLY currently has the higher Sharpe Ratio (1.33 vs 1.11), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.

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