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LLY vs. ALNY
Performance
Return for Risk
Drawdowns
Volatility
Dividends
Financials

Performance

LLY vs. ALNY - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Eli Lilly and Company (LLY) and Alnylam Pharmaceuticals, Inc. (ALNY). The values are adjusted to include any dividend payments, if applicable.

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Returns By Period

In the year-to-date period, LLY achieves a 7.29% return, which is significantly higher than ALNY's -26.53% return. Over the past 10 years, LLY has outperformed ALNY with an annualized return of 33.71%, while ALNY has yielded a comparatively lower 16.55% annualized return.


LLY

1D
1.57%
1M
21.37%
YTD
7.29%
6M
15.58%
1Y
50.32%
3Y*
38.07%
5Y*
39.75%
10Y*
33.71%

ALNY

1D
-3.59%
1M
-0.98%
YTD
-26.53%
6M
-32.06%
1Y
-2.88%
3Y*
15.25%
5Y*
13.17%
10Y*
16.55%
*Multi-year figures are annualized to reflect compound growth (CAGR)

LLY vs. ALNY - Yearly Performance Comparison


2026 (YTD)202520242023202220212020201920182017
LLY
Eli Lilly and Company
7.29%40.25%33.30%60.91%34.26%66.08%31.04%16.14%40.45%17.83%
ALNY
Alnylam Pharmaceuticals, Inc.
-26.53%68.99%22.94%-19.46%40.14%30.48%12.85%57.96%-42.61%239.34%

Correlation

The correlation between LLY and ALNY is 0.17, which is low. Their price movements are largely independent, making them effective diversification partners.


Correlation
Correlation (1Y)
Calculated over the trailing 1-year period

0.17

Correlation (3Y)
Calculated over the trailing 3-year period

0.21

Correlation (5Y)
Calculated over the trailing 5-year period

0.22

Correlation (10Y)
Calculated over the trailing 10-year period

0.24

Correlation (All Time)
Calculated using the full available price history since Jun 2, 2004

0.29

The correlation between LLY and ALNY shifts across timeframes, from 0.17 (1 year) to 0.29 (all time), reflecting how their relationship changes across market environments.

Fundamentals

Market Cap

LLY:

$1.03T

ALNY:

$40.38B

EPS

LLY:

$28.14

ALNY:

$4.26

PE Ratio

LLY:

40.83

ALNY:

68.52

PS Ratio

LLY:

14.28

ALNY:

9.23

PB Ratio

LLY:

33.00

ALNY:

37.55

Total Revenue (TTM)

LLY:

$72.25B

ALNY:

$4.29B

Gross Profit (TTM)

LLY:

$59.75B

ALNY:

$2.51B

EBITDA (TTM)

LLY:

$32.97B

ALNY:

$729.86M

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Return for Risk

LLY vs. ALNY — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

LLY
LLY Risk / Return Rank: 7777
Overall Rank
LLY Sharpe Ratio Rank: 7979
Sharpe Ratio Rank
LLY Sortino Ratio Rank: 7474
Sortino Ratio Rank
LLY Omega Ratio Rank: 7676
Omega Ratio Rank
LLY Calmar Ratio Rank: 7777
Calmar Ratio Rank
LLY Martin Ratio Rank: 7777
Martin Ratio Rank

ALNY
ALNY Risk / Return Rank: 3838
Overall Rank
ALNY Sharpe Ratio Rank: 3939
Sharpe Ratio Rank
ALNY Sortino Ratio Rank: 3535
Sortino Ratio Rank
ALNY Omega Ratio Rank: 3434
Omega Ratio Rank
ALNY Calmar Ratio Rank: 4040
Calmar Ratio Rank
ALNY Martin Ratio Rank: 4040
Martin Ratio Rank
The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

LLY vs. ALNY - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Eli Lilly and Company (LLY) and Alnylam Pharmaceuticals, Inc. (ALNY). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.


LLYALNYDifference
Sharpe ratioReturn per unit of total volatility

+1.41

Sortino ratioReturn per unit of downside risk

+1.75

Omega ratioGain probability vs. loss probability

1.26

1.02

+0.24

Calmar ratioReturn relative to maximum drawdown

2.14

-0.07

+2.21

Martin ratioReturn relative to average drawdown

5.32

-0.12

+5.44

LLY vs. ALNY - Sharpe Ratio Comparison

The current LLY Sharpe Ratio is 1.33, which is higher than the ALNY Sharpe Ratio of -0.08. The chart below compares the historical Sharpe Ratios of LLY and ALNY, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.


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Sharpe Ratios by Period


LLYALNYDifference

Sharpe Ratio (1Y)

Calculated over the trailing 1-year period

1.33

-0.08

+1.41

Sharpe Ratio (5Y)

Calculated over the trailing 5-year period

1.23

0.27

+0.96

Sharpe Ratio (10Y)

Calculated over the trailing 10-year period

1.12

0.31

+0.81

Sharpe Ratio (All Time)

Calculated using the full available price history

0.58

0.32

+0.26

Drawdowns

LLY vs. ALNY - Drawdown Comparison

The maximum LLY drawdown since its inception was -68.24%, smaller than the maximum ALNY drawdown of -83.58%. Use the drawdown chart below to compare losses from any high point for LLY and ALNY.


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Drawdown Indicators


LLYALNYDifference

Max Drawdown

Largest peak-to-trough decline

-68.24%

-83.58%

+15.34%

Max Drawdown (1Y)

Largest decline over 1 year

-23.64%

-42.01%

+18.37%

Max Drawdown (3Y)

Largest decline over 3 years

-34.48%

-42.01%

+7.53%

Max Drawdown (5Y)

Largest decline over 5 years

-34.48%

-42.46%

+7.98%

Max Drawdown (10Y)

Largest decline over 10 years

-34.48%

-59.95%

+25.47%

Current Drawdown

Current decline from peak

0.00%

-40.52%

+40.52%

Average Drawdown

Average peak-to-trough decline

-19.22%

-30.59%

+11.37%

Ulcer Index

Depth and duration of drawdowns from previous peaks

9.49%

23.22%

-13.73%

Volatility

LLY vs. ALNY - Volatility Comparison

Eli Lilly and Company (LLY) and Alnylam Pharmaceuticals, Inc. (ALNY) have volatilities of 9.55% and 9.94%, respectively, indicating that both stocks experience similar levels of price fluctuations. This suggests that the risk associated with both stocks, as measured by volatility, is nearly the same. The chart below showcases a comparison of their rolling one-month volatility.


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Volatility by Period


LLYALNYDifference

Volatility (1M)

Calculated over the trailing 1-month period

9.55%

9.94%

-0.39%

Volatility (6M)

Calculated over the trailing 6-month period

27.05%

26.34%

+0.71%

Volatility (1Y)

Calculated over the trailing 1-year period

38.16%

36.87%

+1.29%

Volatility (5Y)

Calculated over the trailing 5-year period, annualized

32.54%

48.88%

-16.34%

Volatility (10Y)

Calculated over the trailing 10-year period, annualized

30.18%

53.66%

-23.48%

Dividends

LLY vs. ALNY - Dividend Comparison

LLY's dividend yield for the trailing twelve months is around 0.56%, while ALNY has not paid dividends to shareholders.


PositionTTM20252024202320222021202020192018201720162015
ALNY
Alnylam Pharmaceuticals, Inc.
0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%
LLY
Eli Lilly and Company
0.56%0.56%0.67%0.78%1.07%1.23%1.75%1.96%1.94%2.46%2.77%2.37%

Financials

LLY vs. ALNY - Financials Comparison

This section allows you to compare key financial metrics between Eli Lilly and Company and Alnylam Pharmaceuticals, Inc.. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.


Quarterly
Annual

Total Revenue: Total amount of money received from sales and other business activities


0.005.00B10.00B15.00B20.00B20222023202420252026
19.80B
1.17B
(LLY) Total Revenue
(ALNY) Total Revenue
Values in USD except per share items

LLY vs. ALNY - Profitability Comparison

The chart below illustrates the profitability comparison between Eli Lilly and Company and Alnylam Pharmaceuticals, Inc. over time, highlighting three key metrics: Gross Profit Margin, Operating Margin, and Net Profit Margin.

Gross Margin
Operating Margin
Net Margin
Quarterly
Annual

0.0%20.0%40.0%60.0%80.0%20222023202420252026
79.0%
0
Portfolio components
LLY - Gross Margin

Gross margin is calculated as gross profit divided by revenue. For the three months ending on Jun 2026, Eli Lilly and Company reported a gross profit of 15.64B and revenue of 19.80B. Therefore, the gross margin over that period was 79.0%.

ALNY - Gross Margin

Gross margin is calculated as gross profit divided by revenue. For the three months ending on Jun 2026, Alnylam Pharmaceuticals, Inc. reported a gross profit of 0.00 and revenue of 1.17B. Therefore, the gross margin over that period was 0.0%.

LLY - Operating Margin

Operating margin is calculated as operating income divided by revenue. For the three months ending on Jun 2026, Eli Lilly and Company reported an operating income of 9.19B and revenue of 19.80B, resulting in an operating margin of 46.4%.

ALNY - Operating Margin

Operating margin is calculated as operating income divided by revenue. For the three months ending on Jun 2026, Alnylam Pharmaceuticals, Inc. reported an operating income of 268.64M and revenue of 1.17B, resulting in an operating margin of 23.0%.

LLY - Net Margin

Net margin is calculated as net income divided by revenue. For the three months ending on Jun 2026, Eli Lilly and Company reported a net income of 7.40B and revenue of 19.80B, resulting in a net margin of 37.4%.

ALNY - Net Margin

Net margin is calculated as net income divided by revenue. For the three months ending on Jun 2026, Alnylam Pharmaceuticals, Inc. reported a net income of 205.99M and revenue of 1.17B, resulting in a net margin of 17.7%.


Frequently Asked Questions


LLY and ALNY have a correlation of 0.17, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

ALNY has higher volatility (9.94%) compared to LLY (9.55%). In terms of maximum drawdown, LLY dropped -68.24% vs ALNY's -83.58%.

LLY currently has the higher Sharpe Ratio (1.33 vs -0.08), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.

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