BBP vs. AIPO

Last updated Jun 9, 2026

BBP (Virtus LifeSci Biotech Products ETF) and AIPO (Defiance AI & Power Infrastructure ETF) are both exchange-traded funds - BBP is a Health & Biotech Equities fund tracking the LifeSci Biotechnology Products Index, while AIPO is a Building & Construction fund tracking the MarketVector™ US Listed AI and Power Infrastructure Index. Both are passively managed. At a 0.38 correlation, their price movements are largely independent. BBP charges 0.79%/yr vs 0.69%/yr for AIPO.

Performance

BBP vs. AIPO - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Virtus LifeSci Biotech Products ETF (BBP) and Defiance AI & Power Infrastructure ETF (AIPO). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, BBP achieves a 5.23% return, which is significantly lower than AIPO's 42.13% return.

BBP

• 1D: -0.72%
• 1M: -4.70%
• YTD: 5.23%
• 6M: 7.53%
• 1Y: 39.09%
• 3Y*: 15.67%
• 5Y*: 9.36%
• 10Y*: 11.99%

AIPO

• 1D: 0.90%
• 1M: -2.24%
• YTD: 42.13%
• 6M: 32.79%
• 1Y: —
• 3Y*: —
• 5Y*: —
• 10Y*: —

*Multi-year figures are annualized to reflect compound growth (CAGR)

BBP vs. AIPO - Yearly Performance Comparison

	2026 (YTD)	2025
BBP Virtus LifeSci Biotech Products ETF	5.23%	26.43%
AIPO Defiance AI & Power Infrastructure ETF	42.13%	9.46%

Correlation

The correlation between BBP and AIPO is 0.38, which is low. Their price movements are largely independent, making them effective diversification partners.

	Correlation
Correlation (All Time) Calculated using the full available price history since Jul 25, 2025	0.38

BBP vs. AIPO - Sectors Allocation Comparison

Sectors	BBP	AIPO
Healthcare	100.0%	-
Basic Materials	-	-
Communication Services	-	0.5%
Consumer Cyclical	-	-
Consumer Defensive	-	-
Energy	-	6.9%
Financial Services	-	3.6%
Industrials	-	57.1%
Real Estate	-	1.0%
Technology	-	16.5%
Utilities	-	14.4%

Return for Risk

BBP vs. AIPO — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

BBP

BBP Risk / Return Rank: 64
BBP Sharpe Ratio Rank: 54
BBP Sortino Ratio Rank: 56
BBP Omega Ratio Rank: 49
BBP Calmar Ratio Rank: 85
BBP Martin Ratio Rank: 76

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

BBP vs. AIPO - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Virtus LifeSci Biotech Products ETF (BBP) and Defiance AI & Power Infrastructure ETF (AIPO). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	BBP	AIPO	Difference
Sharpe ratio: Return per unit of total volatility	1.65	—	—
Sortino ratio: Return per unit of downside risk	2.42	—	—
Omega ratio: Gain probability vs. loss probability	1.28	—	—
Calmar ratio: Return relative to maximum drawdown	4.23	—	—
Martin ratio: Return relative to average drawdown	12.99	—	—
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

Sharpe Ratios by Period

	BBP	AIPO	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	1.65	—	—
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	0.36	—	—
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	0.44	—	—
Sharpe Ratio (All Time) Calculated using the full available price history	0.39	1.89	-1.50

Drawdowns

BBP vs. AIPO - Drawdown Comparison

The maximum BBP drawdown since its inception was -44.32%, which is greater than AIPO's maximum drawdown of -17.31%. Use the drawdown chart below to compare losses from any high point for BBP and AIPO.

Drawdown Indicators

	BBP	AIPO	Difference
Max Drawdown Largest peak-to-trough decline	-44.32%	-17.31%	-27.01%
Max Drawdown (1Y) Largest decline over 1 year	-9.28%	—	—
Max Drawdown (3Y) Largest decline over 3 years	-26.09%	—	—
Max Drawdown (5Y) Largest decline over 5 years	-38.28%	—	—
Max Drawdown (10Y) Largest decline over 10 years	-44.32%	—	—
Current Drawdown Current decline from peak	-6.96%	-7.56%	+0.60%
Average Drawdown Average peak-to-trough decline	-12.02%	-4.40%	-7.62%
Ulcer Index Depth and duration of drawdowns from previous peaks	3.02%	—	—

Volatility

Volatility by Period

	BBP	AIPO	Difference
Volatility (1M) Calculated over the trailing 1-month period	6.81%	—	—
Volatility (6M) Calculated over the trailing 6-month period	18.58%	—	—
Volatility (1Y) Calculated over the trailing 1-year period	23.85%	34.68%	-10.83%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	26.34%	34.68%	-8.34%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	27.41%	34.68%	-7.27%

BBP vs. AIPO - Expense Ratio Comparison

BBP has a 0.79% expense ratio, which is higher than AIPO's 0.69% expense ratio.

Dividends

BBP vs. AIPO - Dividend Comparison

BBP has not paid dividends to shareholders, while AIPO's dividend yield for the trailing twelve months is around 0.01%.

Position	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015
AIPO Defiance AI & Power Infrastructure ETF	0.01%	0.01%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%
BBP Virtus LifeSci Biotech Products ETF	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.18%	0.00%	1.29%

Frequently Asked Questions

Can I hold both BBP and AIPO in my portfolio?

BBP and AIPO have a correlation of 0.38, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which ETF is better, BBP or AIPO?

On fees, AIPO is cheaper at 0.69% per year. The better choice depends on whether you care most about return, fees, risk, or income.

Which ETF is cheaper, BBP or AIPO?

AIPO is cheaper with a 0.69% expense ratio, compared with 0.79% for BBP.

Which ETF pays a higher dividend yield, BBP or AIPO?

AIPO has the higher dividend yield at 0.01%, compared with 0.00% for BBP.

What is the main difference between BBP and AIPO?

BBP is categorized as Health & Biotech Equities, while AIPO is Building & Construction. BBP tracks LifeSci Biotechnology Products Index, while AIPO tracks MarketVector™ US Listed AI and Power Infrastructure Index. They also come from different issuers: Virtus Investment Partners and Defiance. Their fees differ too: 0.79% for BBP and 0.69% for AIPO.