ALGN vs. CPRX
ALGN (Align Technology, Inc.) and CPRX (Catalyst Pharmaceuticals, Inc.) are both stocks. Both are in the Healthcare sector — ALGN in Medical Devices, CPRX in Biotechnology. Over the past 10 years, ALGN returned 8.12%/yr vs 48.01%/yr for CPRX. At a 0.19 correlation, their price movements are largely independent.
Performance
ALGN vs. CPRX - Performance Comparison
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Returns By Period
In the year-to-date period, ALGN achieves a 10.18% return, which is significantly lower than CPRX's 34.02% return. Over the past 10 years, ALGN has underperformed CPRX with an annualized return of 8.12%, while CPRX has yielded a comparatively higher 48.01% annualized return.
ALGN
- 1D
- 2.57%
- 1M
- 1.94%
- YTD
- 10.18%
- 6M
- 9.11%
- 1Y
- -4.74%
- 3Y*
- -17.32%
- 5Y*
- -21.72%
- 10Y*
- 8.12%
CPRX
- 1D
- 0.03%
- 1M
- 0.42%
- YTD
- 34.02%
- 6M
- 35.06%
- 1Y
- 20.91%
- 3Y*
- 39.11%
- 5Y*
- 40.76%
- 10Y*
- 48.01%
ALGN vs. CPRX - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | |
|---|---|---|---|---|---|---|---|---|---|---|
ALGN Align Technology, Inc. | 10.18% | -25.11% | -23.90% | 29.92% | -67.91% | 22.98% | 91.51% | 33.24% | -5.74% | 131.13% |
CPRX Catalyst Pharmaceuticals, Inc. | 34.02% | 11.84% | 24.15% | -9.62% | 174.74% | 102.69% | -10.93% | 95.31% | -50.90% | 272.38% |
Correlation
The correlation between ALGN and CPRX is 0.22, which is low. Their price movements are largely independent, making them effective diversification partners.
| Correlation | |
|---|---|
Correlation (1Y) Calculated over the trailing 1-year period | 0.22 |
Correlation (3Y) Calculated over the trailing 3-year period | 0.23 |
Correlation (5Y) Calculated over the trailing 5-year period | 0.28 |
Correlation (10Y) Calculated over the trailing 10-year period | 0.26 |
Correlation (All Time) Calculated using the full available price history since Nov 9, 2006 | 0.19 |
Fundamentals
ALGN:
$12.32B
CPRX:
$3.97B
ALGN:
$5.96
CPRX:
$1.74
ALGN:
28.85
CPRX:
17.98
ALGN:
3.03
CPRX:
6.67
ALGN:
2.97
CPRX:
3.92
ALGN:
$4.10B
CPRX:
$596.96M
ALGN:
$2.77B
CPRX:
$378.23M
ALGN:
$776.15M
CPRX:
$313.50M
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Return for Risk
ALGN vs. CPRX — Risk / Return Rank
ALGN
CPRX
ALGN vs. CPRX - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for Align Technology, Inc. (ALGN) and Catalyst Pharmaceuticals, Inc. (CPRX). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
| ALGN | CPRX | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | -0.72 | ||
| Sortino ratioReturn per unit of downside risk | -0.82 | ||
| Omega ratioGain probability vs. loss probability | 1.05 | 1.14 | -0.09 |
| Calmar ratioReturn relative to maximum drawdown | -0.12 | 0.77 | -0.89 |
| Martin ratioReturn relative to average drawdown | -0.20 | 1.40 | -1.60 |
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month. | |||
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Sharpe Ratios by Period
| ALGN | CPRX | Difference | |
|---|---|---|---|
Sharpe Ratio (1Y)Calculated over the trailing 1-year period | -0.09 | 0.63 | -0.72 |
Sharpe Ratio (5Y)Calculated over the trailing 5-year period | -0.44 | 0.86 | -1.30 |
Sharpe Ratio (10Y)Calculated over the trailing 10-year period | 0.17 | 0.80 | -0.63 |
Sharpe Ratio (All Time)Calculated using the full available price history | 0.16 | 0.09 | +0.07 |
Drawdowns
ALGN vs. CPRX - Drawdown Comparison
The maximum ALGN drawdown since its inception was -92.30%, roughly equal to the maximum CPRX drawdown of -94.25%. Use the drawdown chart below to compare losses from any high point for ALGN and CPRX.
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Drawdown Indicators
| ALGN | CPRX | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -92.30% | -94.25% | +1.95% |
Max Drawdown (1Y)Largest decline over 1 year | -39.73% | -27.29% | -12.44% |
Max Drawdown (3Y)Largest decline over 3 years | -67.59% | -27.29% | -40.30% |
Max Drawdown (5Y)Largest decline over 5 years | -82.89% | -45.37% | -37.52% |
Max Drawdown (10Y)Largest decline over 10 years | -82.89% | -64.87% | -18.02% |
Current DrawdownCurrent decline from peak | -76.43% | -0.16% | -76.27% |
Average DrawdownAverage peak-to-trough decline | -37.65% | -52.02% | +14.37% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 23.90% | 14.95% | +8.95% |
Volatility
ALGN vs. CPRX - Volatility Comparison
Align Technology, Inc. (ALGN) has a higher volatility of 11.85% compared to Catalyst Pharmaceuticals, Inc. (CPRX) at 0.44%. This indicates that ALGN's price experiences larger fluctuations and is considered to be riskier than CPRX based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| ALGN | CPRX | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 11.85% | 0.44% | +11.41% |
Volatility (6M)Calculated over the trailing 6-month period | 28.46% | 23.50% | +4.96% |
Volatility (1Y)Calculated over the trailing 1-year period | 52.81% | 33.58% | +19.23% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 49.56% | 47.80% | +1.76% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 49.06% | 60.47% | -11.41% |
Dividends
ALGN vs. CPRX - Dividend Comparison
Neither ALGN nor CPRX has paid dividends to shareholders.
Financials
ALGN vs. CPRX - Financials Comparison
This section allows you to compare key financial metrics between Align Technology, Inc. and Catalyst Pharmaceuticals, Inc.. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.
Total Revenue: Total amount of money received from sales and other business activities
ALGN vs. CPRX - Profitability Comparison
ALGN - Gross Margin
Gross margin is calculated as gross profit divided by revenue. For the three months ending on Jun 2026, Align Technology, Inc. reported a gross profit of 736.59M and revenue of 1.04B. Therefore, the gross margin over that period was 70.8%.
CPRX - Gross Margin
Gross margin is calculated as gross profit divided by revenue. For the three months ending on Jun 2026, Catalyst Pharmaceuticals, Inc. reported a gross profit of 0.00 and revenue of 149.39M. Therefore, the gross margin over that period was 0.0%.
ALGN - Operating Margin
Operating margin is calculated as operating income divided by revenue. For the three months ending on Jun 2026, Align Technology, Inc. reported an operating income of 141.96M and revenue of 1.04B, resulting in an operating margin of 13.7%.
CPRX - Operating Margin
Operating margin is calculated as operating income divided by revenue. For the three months ending on Jun 2026, Catalyst Pharmaceuticals, Inc. reported an operating income of 73.23M and revenue of 149.39M, resulting in an operating margin of 49.0%.
ALGN - Net Margin
Net margin is calculated as net income divided by revenue. For the three months ending on Jun 2026, Align Technology, Inc. reported a net income of 112.77M and revenue of 1.04B, resulting in a net margin of 10.8%.
CPRX - Net Margin
Net margin is calculated as net income divided by revenue. For the three months ending on Jun 2026, Catalyst Pharmaceuticals, Inc. reported a net income of 63.73M and revenue of 149.39M, resulting in a net margin of 42.7%.
Frequently Asked Questions
ALGN and CPRX have a correlation of 0.22, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
ALGN has higher volatility (11.85%) compared to CPRX (0.44%). In terms of maximum drawdown, ALGN dropped -92.30% vs CPRX's -94.25%.
CPRX currently has the higher Sharpe Ratio (0.63 vs -0.09), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.
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